Flinders Centre for Clinical Change and Health Care Research was founded to address the challenges of the ageing Australian population combined with the expanding costs of providing optimal health care. Our key strategic focus, research direction and collaborations are toward the effective and cost efficient delivery of clinical therapies and facilitation of their translation into improved clinical practice and outcomes. Members of the Centre undertake and publish high value research in one or more of the following areas of focus:
- prevention and management of chronic conditions
- implementation research
- evidence based clinical practice
- health economics
Prevention and management of chronic conditions
Chronic conditions refer to those people with long term medical (diseases), psychiatric disorders and disabilities or combinations of these in the one person. The primary aim of researchers engaged in this theme is to improve the health outcomes of people with chronic conditions. As many chronic conditions are caused or exacerbated by individual behaviour and psychosocial factors, prevention and management of chronic conditions have considerable overlap. Therefore, this theme focuses on the full range of research including:
- underlying pathology, mechanisms or aetiology
- prevention
- clinical treatments
- management by teams of health professionals from all health disciplines.
- the role of the person with the chronic condition
- the role of family and carers in the management of their condition(s)
- health system factors that influence health outcomes at the individual and population level.
Implementation research
Research findings cannot change health outcomes unless they are adopted. Implementation research involves the study of changing behaviour and maintaining change. It is the scientific study of methods to:
- promote the systematic uptake of clinical research findings and evidence-based practice into routine practice
- improve the quality (effectiveness, reliability, safety, appropriateness, equity and efficiency) of healthcare.
Evidence based clinical practice
This research theme seeks to evaluate the current disease-specific barriers to care from the perspective of the patient, the clinician and the health care system.
The delivery of modern medical care is informed by a substantial evidence-base. Often these data have been assimilated into clinical practice guidelines, yet challenges in the translation of evidence remain. Factors contributing to this set of barriers include:
- patient complexity
- limited resources
- health service contextual factors.
Health economics
The main purpose of this theme is the examination of cost effectiveness of health care interventions and services, in particular, our focus is on:
- the measurement and valuation of health outcomes for economic evaluation
- the economic evaluation of new and emerging health care technologies
- the methodology and application of discrete choice experiments (DCE) for the quantification of patient and general population preferences for health and health care treatments and services
Current health economics collaborations include:
- A health economic model for the development and evaluation of innovations in aged care
- Adolescent population health: application of Best-Worst Scaling Discrete Choice Experiments to value health states for use in economic evaluation
- Economic evaluation of OPAL (Obesity Prevention and Lifestyle)
- Economic evaluation of acupuncture to improve live birth rates for women undergoing IVF
- Engaging the public in healthcare decision making: Quantifying preferences for healthcare through Citizens' Juries

