Head amplifiers

Biomedical Research Support

Head amplifiers and slip rings

FBE, Flinders Biomedical Engineering, have developed devices for researchers in the Flinders University School of Medicine to assist monitoring of up to 8 channels of EEG, ECG, EOG, and temperature. The devices are made of 18-channel slip-ring assemblies and head amplifiers.

Devices developed by Biomedical Engineering

Head Amplifiers

Miniature physiological amplifiers suitable for small animals are completely manufactured in-house. They are used for collection of physiological signals such as ECG, EEG, EMG, EOG, ion concentration (ion-selective (pH) electrodes), flow and temperature. Metal gooseneck shrouding protects the signal cables. A slip ring system is used to couple the signals to the recording equipment located outside the Faraday cage, while allowing the animals to freely move around. [BME1449, BME1421 & BME1420]

Slipring assembly

The slipring assembly enables physiological monitoring of rodents while free to move around. [BME1335]


Head amplifier EEG

Head amp inside

Head amp double board

Head amp side view

Slip ring

Publications using BME developed devices

Head amps, ECG

Ootsuka Y, de Menezes RC, Zaretsky DV, Alimoradian A, Hunt J, Stefanidis A, Oldfield BJ, Blessing WW. Brown adipose tissue thermogenesis heats brain and body as part of the brain-coordinated ultradian basic rest-activity cycle. Neuroscience 2009;164(2):849-61

Ootsuka Y, Blessing WW, Nalivaiko E. Selective blockade of 5-HT2A receptors attenuates the increased temperature response in brown adipose tissue to restraint stress in rats. Stress. 2008;11(2):125-33.

Head amps, epilepsy

Broberg M, Pope KJ, Nilsson M, Wallace A, Wilson J, Willoughby JO. Preseizure increased gamma electroencephalographic activity has no effect on extracellular potassium or calcium. J Neurosci Res. 2007 Mar;85(4):906-18.

Broberg M, Pope KJ, Lewis T, Olsson T, Nilsson M, Willoughby JO. Cell swelling precedes seizures induced by inhibition of astrocytic metabolism. Epilepsy Res. 2008 Aug;80(2-3):132-41. Epub 2008 Apr 28.

Head amps, flow

Ootsuka Y, Heidbreder CA, Hagan JJ, Blessing WW. Dopamine D2 receptor stimulation inhibits cold-initiated thermogenesis in brown adipose tissue in conscious rats. Neuroscience 2007;147(1):127-35

Head amps, pharmacology

Hemsley KM, Crocker AD. Atropine reduces raclopride-induced muscle rigidity by acting in the ventral region of the striatum. Eur J Pharmacol. 2002 Jan 11;434(3):117-23.

Hemsley KM, Crocker AD. Changes in muscle tone are regulated by D1 and D2 dopamine receptors in the ventral striatum and D1 receptors in the substantia nigra. Neuropsychopharmacology. 2001 Oct;25(4):514-26.

Crocker AD, Hemsley KM. An animal model of extrapyramidal side effects induced by antipsychotic drugs: relationship with D2 dopamine receptor occupancy. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Apr;25(3):573-90.