Uveitis infections

We’re at the forefront of the global quest to greater understand and improve treatment of intraocular inflammatory disease. A strong focus of our research includes the parasite Toxoplasma gondii.

Members of our team also collaborate on international projects relating to the long term ophthalmological effects that may be experienced following infection with viruses such as Ebola.

Further research examines the involvement of adhesion molecules in the development of noninfectious forms of the disease.

Watch the video - Ebola's Adelaide Connection

 

Funding

Funding provided through a Flinders University top-up grant:

  • Toxoplasma gondii infection of human retinal pigment.

Funding provided through the National Health and Medical Research Council:

  • 1066235 Toxoplasma gondii Infection of Human Retinal Pigment Epithelium
  • 1123684 Regulation of ICAM-1 Expression in Human Retinal Endothelial Cells

Funding provided through the Australia Research Council

  • Molecular activities of retinal endothelial cells, retinal disease processes, biological therapies to address efficacy and safety deficiencies of current treatments

Featured publications

  • Shantha JG, Crozier I, Varkey JB, et al. Long-term Management of Panuveitis and Iris Heterochromia in an Ebola Survivor. Ophthalmology. 2016 Dec; 123(12):2626-2628.e2. doi: 10.1016/j.ophtha.2016.07.013. Epub 2016 Sep 1. No abstract available.
  • Faridi A, Yeh S, Suhler EB, et al. Retinal detachment associated with ocular toxoplasmosis. Retina. 2015 Feb; 35(2):358-63. doi: 10.1097/IAE.0000000000000279.
  • Bharadwaj AS, Stempel AJ, Olivas A, et al. Molecular Signals Involved in Human B Cell Migration into the Retina: In Vitro Investigation of ICAM-1, VCAM-1, and CXCL13. Ocul Immunol Inflamm. 2016 Jul 5:1-9. [Epub ahead of print].