
| Phone: | +61 8 82044123 |
| Email: | helen.brereton@flinders.edu.au |
| Location: | School of Medicine (5D:214) |
| Postal address: | GPO Box 2100, Adelaide 5001, South Australia |
Brice, S., Kirk, K., Brereton, H.M., Coster, D.J., & Williams, K.A., 2012. The influence of cervical and thoracic lymphadenectomy on corneal allograft rejection in inbred rats. British Journal of Ophthalmology, 96(3), 448-450.
Parker, D., Coster, D.J., Brereton, H.M., Hart, P., Koldej, R., Anson, D., & Williams, K.A., 2010. Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea. Clinical and Experimental Ophthalmology, 38(4), 405-413.
van Wijngaarden, P., Brereton, H.M., Coster, D.J., & Williams, K.A., 2010. Hereditary influences in oxygen-induced retinopathy in the rat. Documenta Ophthalmologica, 120, 87-97.
Irani, Y., Brereton, H.M., Tilton, R.G., Coster, D.J., & Williams, K.A., 2009. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor. Hybridoma, 28(3), 205-209.
Parker, D., Brereton, H.M., Coster, D.J., & Williams, K.A., 2009. The potential of viral vector-mediated gene transfer to prolong corneal allograft survival. Current Gene Therapy, 9(1), 33-44.
Williams, K.A., Brereton, H.M., & Coster, D.J., 2009. Prospects for genetic modulation of corneal graft survival. Eye, 23(10), 1904-1909.
Parker, D., Brereton, H.M., Klebe, S., Coster, D.J., & Williams, K.A., 2009. A steroid-inducible promoter for the cornea. British Journal of Ophthalmology, 93(9), 1255-1259.
Tea, M.N., Fogarty, R.D., Brereton, H.M., Michael, M.Z., Van der Heok, M.B., Tsykin, A., Coster, D.J., & Williams, K.A., 2009. Gene expression microarray analysis of early oxygen-induced retinopathy in the rat. Journal of Ocular Biology, Diseases, and Informatics, 2(4), 190-201.
Irani, Y., Tea, M.N., Tilton, R.G., Coster, D.J., Williams, K.A., & Brereton, H.M., 2008. PCR amplification of the functional immunoglobulin heavy chain variable gene from a hybridoma in the presence of two aberrant transcripts. Journal of Immunological Methods, 36(2), 246-250.
Parker, D., Kaufmann, C., Brereton, H.M., Anson, D.S., Francis-Staite, L., Jessup, C.F., Marshall, K.A., Tan, C., Koldej, R., Coster, D.J., et al., 2007. Lentivirus-mediated gene transfer to the rat, ovine and human cornea. Gene Therapy, 14(9), 760-767.
Brice, S., Kirk, K., Brereton, H.M., Coster, D.J., & Williams, K.A., 2012. The influence of cervical and thoracic lymphadenectomy on corneal allograft rejection in inbred rats. British Journal of Ophthalmology, 96(3), 448-450.
Parker, D., Coster, D.J., Brereton, H.M., Hart, P., Koldej, R., Anson, D., & Williams, K.A., 2010. Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea. Clinical and Experimental Ophthalmology, 38(4), 405-413.
van Wijngaarden, P., Brereton, H.M., Coster, D.J., & Williams, K.A., 2010. Hereditary influences in oxygen-induced retinopathy in the rat. Documenta Ophthalmologica, 120, 87-97.
Irani, Y., Brereton, H.M., Tilton, R.G., Coster, D.J., & Williams, K.A., 2009. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor. Hybridoma, 28(3), 205-209.
Parker, D., Brereton, H.M., Coster, D.J., & Williams, K.A., 2009. The potential of viral vector-mediated gene transfer to prolong corneal allograft survival. Current Gene Therapy, 9(1), 33-44.
Parker, D., Brereton, H.M., Klebe, S., Coster, D.J., & Williams, K.A., 2009. A steroid-inducible promoter for the cornea. British Journal of Ophthalmology, 93(9), 1255-1259.
Tea, M.N., Fogarty, R.D., Brereton, H.M., Michael, M.Z., Van der Heok, M.B., Tsykin, A., Coster, D.J., & Williams, K.A., 2009. Gene expression microarray analysis of early oxygen-induced retinopathy in the rat. Journal of Ocular Biology, Diseases, and Informatics, 2(4), 190-201.
Williams, K.A., Brereton, H.M., & Coster, D.J., 2009. Prospects for genetic modulation of corneal graft survival. Eye, 23(10), 1904-1909.
Irani, Y., Tea, M.N., Tilton, R.G., Coster, D.J., Williams, K.A., & Brereton, H.M., 2008. PCR amplification of the functional immunoglobulin heavy chain variable gene from a hybridoma in the presence of two aberrant transcripts. Journal of Immunological Methods, 36(2), 246-250.
Parker, D., Kaufmann, C., Brereton, H.M., Anson, D.S., Francis-Staite, L., Jessup, C.F., Marshall, K.A., Tan, C., Koldej, R., Coster, D.J., et al., 2007. Lentivirus-mediated gene transfer to the rat, ovine and human cornea. Gene Therapy, 14(9), 760-767.
Brereton, H.M., Chamberlain, D., Yang, R., Tea, M.N., McNeil, S., Coster, D.J., & Williams, K.A., 2007. Single chain antibody fragments for ocular use produced at high levels in a commercial wheat variety. Journal of Biotechnology, 129(3), 539-546.
van Wijngaarden, P., Brereton, H.M., Coster, D.J., & Williams, K.A., 2007. Genetic influences on susceptibility to oxygen-induced retinopathy. Investigative Ophthalmology and Visual Science, 48(4), 1761-1766.
van Wijngaarden, P., Brereton, H.M., Gibbins, I.L., Coster, D.J., & Williams, K.A., 2007. Kinetics of strain-dependent differential gene expression in oxygen-induced retinopathy in the rat. Experimental Eye Research, 85(4), 508-517.
van Wijngaarden, P., Brereton, H.M., Coster, D.J., & Williams, K.A., 2007. Stability of housekeeping gene expression in the rat retina during exposure to cyclic hyperoxia. Molecular Vision, 13, 1508-1515.
Brereton, H.M., Taylor, S.D., Farrall, A., Hocking, D., Thiel, M., Tea, M.N., Coster, D.J., & Williams, K.A., 2005. Influence of format on in vitro penetration of antibody fragments through porcine cornea. British Journal of Ophthalmology, 89(9), 1205-1209.
Jessup, C.F., Brereton, H.M., Coster, D.J., & Williams, K.A., 2005. In vitro adenovirus mediated gene transfer to the human cornea. British Journal of Ophthalmology, 89(6), 658-661.
Jessup, C.F., Brereton, H.M., Sykes, P.J., Thiel, M., Coster, D.J., & Williams, K.A., 2005. Local gene transfer to modulate rat corneal allograft rejection. Investigative Ophthalmology and Visual Science, 46(5), 1675-1681.
Turner, M.L., Cockerell, E.J., Brereton, H.M., Badenoch, P.R., Tea, M.N., Coster, D.J., & Williams, K.A., 2005. Antigens of selected Acanthamoeba species detected with monoclonal antibodies. International Journal For Parasitology, 35(9), 981-990.
Williams, K.A., Brereton, H.M., Farrall, A., Standfield, S., Taylor, S.D., Kirk, L., & Coster, D.J., 2005. Topically applied antibody fragments penetrate into the back of the rabbit eye. Eye, 19(8), 910-913.
van Wijngaarden, P., Coster, D.J., Brereton, H.M., Gibbins, I.L., & Williams, K.A., 2005. Strain-dependent differences in oxygen-induced retinopathy in the inbred rat. Investigative Ophthalmology and Visual Science, 46(4), 1445-1452.
Ruengrairatanaroje, P., Hahn, M.A., Brereton, H.M., Zhang, L., Froscio, M., Petronijevic, T., & Barritt, G.J., 2004. Development of a tetracycline-inducible system for expression of the Ca2+ permeable TRPL channel and the killing of prostate cancer cells. Cancer Therapy, 2(B), 389-402.
Ong, H.L., Brereton, H.M., Harland, M.L., & Barritt, G.J., 2003. Evidence for the expression of transient receptor potential proteins in guinea pig airway smooth muscle cells. Respirology, 8(1), 23-32.
Zhang, L., Brereton, H.M., Hahn, M.A., Froscio, M., Tilley, W.D., Brown, M.P., & Barritt, G.J., 2003. Expression of Drosophila Ca2+ permeable transient receptor potential-like channel protein in a prostate cancer cell line decreases cell survival. Cancer Gene Therapy, 10(8), 611-625.
Ong, H.L., Chen, J., Chataway, T.K., Brereton, H.M., Zhang, L., Downs, T., Tsiokas, L., & Barritt, G.J., 2002. Specific detection of the endogenous transient receptor potential (TRP)-1 protein in liver and airway smooth muscle cells using immunoprecipitation and Western-blot analysis. Biochemical Journal, 364(8), 641-648.
Thiel, M., Coster, D.J., Standfield, S., Brereton, H.M., Mavrangelos, C., Zola, H., Taylor, S., Yusim, A., & Williams, K.A., 2002. Penetration of engineered antibody fragments into the eye. Clinical and Experimental Immunology, 128(1), 67-74.
Rychkov, G., Brereton, H.M., Harland, M.L., & Barritt, G.J., 2001. Plasma Membrane Ca2+ Release-Activated Ca2+ Channels with a High Selectivity for Ca2+ Identified by Patch-Clamp Recording in Rat Liver Cells. Hepatology, 33(4), 938-947.
Tesfai, Y., Brereton, H.M., & Barritt, G.J., 2001. A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein. Biochemical Journal, 358, 717-726.
Brereton, H.M., Chen, J., Rychkov, G., Harland, M.L., & Barritt, G.J., 2001. Maitotoxin activates an endogenous non-selective cation channel and is an effective initiator of the activation of the heterologously expressed hTRPC-1 (transient receptor potential) non-selective cation channel in H4-IIE liver cells. Biochimica et Biophysica Acta-Molecular Cell Research, 1540, 107-126.
Klebe, S., Parker, D., Clarke, A., Brereton, H.M., Coster, D.J., & Williams, K.A., 2008. Efficacy of a steroid-inducible promoter for lentivirus-mediated transduction of the cornea [abstract 29]. Transplantation, 86(Suppl. 2), 10-10.
Parker, D., Klebe, S., Brereton, H.M., Coster, D.J., Anson, D., & Williams, K.A., 2008. Lentivirus-mediated gene transfer to the ovine and human cornea [abstract 30]. Transplantation, 86(Suppl. 2), 10-11.
Brice, S., Mortimer, L.A., Tan, C., Anson, D., Brereton, H.M., & Williams, K.A., 2008. Lentiviral gene transfer to the rat cornea [abstract 917]. Transplantation, 86(Suppl. 2), 319-319.
Parker, D., Kaufmann, C., Brereton, H.M., Anson, D.S., Francis-Staite, L., Coster, D.J., & Williams, K.A., 2007. Lentivirus-mediated gene transfer to the rat, ovine and human cornea. Asia-ARVO Meeting on Research in Vision and Ophthalmology.
Parker, D., Kaufmann, C., Brereton, H.M., Anson, D.S., Francis-Staite, L., Jessup, C.F., Marshall, K.A., Tan, C., Koldej, R., Coster, D.J., et al., 2007. Lentivirus-mediated gene transfer to the rat, ovine and human cornea. The Journal of Gene Medicine: Abstracts from the 5th Australasian Gene Therapy Society Meeting, 9(6), 533-534.
Brereton, H.M., Sharma, S., Mortimer, L.A., Tea, M.N., van Wijngaarden, P., Coster, D.J., & Williams, K.A., 2005. Development of antibody fragments for topical treatment of retinal neovascularization. Proceedings of ComBio2005, 133-133.
Brereton, H.M., Farrall, A., Taylor, S., Coster, D.J., & Williams, K.A., 2004. Penetration of antibody fragments across the cornea and into the posterior segment of the eye. Experimental Eye Research, 79.
van Wijngaarden, P., Brereton, H.M., Coster, D.J., Gibbins, I.L., & Williams, K.A., 2004. Strain-associated angiogenic heterogeneity amongst inbred rats in a model of oxygen-induced retinopathy. EXPERIMENTAL EYE RESEARCH.
Williams, K.A., Klebe, S., Jessup, C.F., Francis-Staite, L., Brereton, H.M., Anson, D.S., & Coster, D.J., 2004. Strategies for improving experimental corneal graft outcomes. EXPERIMENTAL EYE RESEARCH.
Sharma, S., Brereton, H.M., Coster, D.J., & Williams, K.A., 2004. Stable cell lines as a tool for assaying anti-VEGFR2 antibody specificity. EXPERIMENTAL EYE RESEARCH, 79(Supp).
Jessup, C.F., Brereton, H.M., Sykes, P.J., Thiel, M., Coster, D.J., & Williams, K.A., 2004. Modulation of antigen presentation and co-simulation during rat corneal allograft rejection. EXPERIMENTAL EYE RESEARCH.
Brereton, H.M., Turner, M.L., Cockerill, E.J., Bodenoch, P.R., Coster, D.J., & Williams, K.A., 2004. The production of antibody fragments for the diagnosis of acanthamoeba keratitis. Proceedings of ComBio 2004, 70-70.
Brereton, H.M., Farrall, A., Taylor, S., Thiel, M., Coster, D.J., & Williams, K.A., 2004. Penetration of antibody fragments across the cornea and into the posterior segment of the eye. Proceedings of ComBio 2004, 70-70.
Jessup, C.F., Brereton, H.M., Sykes, P.J., Thiel, M., Coster, D.J., & Williams, K.A., 2003. Ex vivo gene transfer to donor rat corneas (Abstract). Transplantation Society of Australia and New Zealand.
Barritt, G.J., Tesfai, Y., & Brereton, H.M., 2003. Transient receptor potential (TRP) proteins as non-selective cation channels in PC12 cells (an adrenal chromaffin cell line). Proceedings of the Australian Neurocience Society, 14, SYM-05-01-SYM-05-01.
Chen, J., Chataway, T.K., Brereton, H.M., Zhang, L., Downs, T., Tsiokas, L., & Barritt, G.J., 2002. Detection of the endogenous TRPC1 protein in liver cells using a combined immunoprecipitation and western blot strategy. FASEB 2002 Summer Research Conference: Calcium and Cell Function.
Brereton, H.M., Standfield, S., Hallsworth, P.G., Coster, D.J., Williams, K.A., Teteris, S.A., & Farrall, A., 2002. Antibody fragments for the treatment and diagnosis of herpetic eye disease. Proceedings of ComBio 2002.
Ong, H.L., Chataway, T.K., Brereton, H.M., Tsiokas, L., Downs, T., & Barritt, G.J., 2002. Evidence for low expression of multiple TRP proteins in guinea pig airway smooth muscle cells. FASEB 2002 Summer Research Conference: Calcium and Cell Function.
Ong, H.L., Brereton, H.M., Harland, M.L., Chataway, T.K., & Barritt, G.J., 2001. Expression of TRP-1 Protein (A non-selective cation channel) in airway smooth muscle cells: studies with a new antibody. Proceedings of the Australian Society for Medical Research SA Division Annual Scientific Meeting.
Jessup, C.F., Brereton, H.M., Coster, D.J., & Williams, K.A., 2004. Ocular tissue modification. Flinders University.
Sharma, S., Brereton, H.M., Coster, D.J., & Williams, K.A., 2004. Stable cell lines as a tool for assaying anti-VEGFR2 antibody specificity. Proceedings of the International Society for Eye Research.