Position

Professor of Cardiology
College of Medicine and Public Health

Biography

Derek Chew is a clinical and interventional cardiologist as well as a clinical trialist and outcomes researcher in cardiovascular medicine. He has completed a Masters of Public Health at the Harvard School of Public Health in quantitative methods. He is a Senior Principal Research Fellow in Cardiovascular Outcomes Research, and is the Regional Head of Cardiology for the Adelaide Health Service (Southern Region). Derek is the Head of the Flinders Clinical Trial Centre, and Chair of the Statewide Cardiology Clinical Network. His clinical and research career is centred on the translation of current and future therapies and technologies in cardiology to improved patient outcomes in a clinically effective manner.

Qualifications

MBBS, MPH, FRACP

Key responsibilities

Edwards Heart Foundation Senior Research Fellow
Professor of Cardiology, Flinders University
Regional Director of Cardiology, Department of Cardiovascular Medicine, Adelaide Health Service (Southern Region)
Head, Flinders Centre for Clinical Change & Health Care Research

Research interests

With the expanding array of therapeutic options available for the clinical care of patients presenting with cardiovascular disease, optimal and cost-effective clinical outcomes will require, not only innovations in pharmacology and device development, but also their careful and evidence-based application to the clinical community. These choices and recommendations can be informed by careful, well-conducted clinical research within the context of current day clinical practice. Derek seeks to design and undertake clinical studies to inform these choices, improve the delivery of proven therapies, identify clinical groups within the entire Australian community that are not currently well served by technologies/therapies and ultimately optimise patient outcomes.

Publications

  • Chew, D. (2011). Anticoagulation in Percutaneous Coronary Intervention. In EJ Topol, PS Teirstein, ed. Textbook of Interventional Cardiology. 6th ed. USA: Saunders, pp. 113-125.
    [Web Link]
  • Chew, D. and Huynh, L. (2011). Applying evidence based medicine, guidelines and clinical pathways in the Coronary Care Unit. In Peter L Thompson, ed. Coronary Care Manual, 2nd Edition. 2nd ed. Chatswood, New South Wales: Elsevier Australia, pp. 12-18.
    [Web Link]
  • Chew, D. (2008). Anticoagulation in PCI. In Eric J Topol, ed. Textbook of Interventional Cardiology 5th Edition. USA: Saunders Elsevier, pp. 165-182.
    [Web Link]
  • Lehman, S., Chew, D.P. and White, H.D. (2008). Glycoprotein IIb/IIIa Inhibitors. In Deepak L Bhatt, ed. Platelets in Cardiovascular Disease. London: Imperial College Press, pp. 65-86.
  • Chew, D., Lehman, S. and White, H. (2007). Direct Thrombin inhibition in Percutaneous Coronary Intervention. In Nicholas N Kipshidze, Jawed Fareed, Jeffrey W. Moses, Patrick W Serruys and Cathy Kennedy, ed. Textbook of Interventional Cardiovascular Pharmacology. UK: CRC Press, pp. 85-92.
    [Web Link]
  • Chew, D. (2006). Platelets, Anti-platelet therapy and Inflammation. In Ridker & Rafai, ed. CRP: Atherothrombosis and Cardiovascular risk. NA: NA.
  • Chew, D. and White, H. (2004). Pathophysiology, Classification and Clinical Features of ACS. In Deepak L Bhatt & Marcus D Flather, ed. Handbook of Acute Coronary Syndromes. United Kingdom: Remedica Publishing, pp. 1-22.
    [Web Link]
  • Chew, D. (2002). Anti-thrombin Therapy in Percutaneous Coronary Intervention. In NA, ed. The Year in Interventional Cardiology. UK: CRC Press, pp. 30-38.
    [Web Link]
  • Chew, D. and Lincoff, A. (2002). Adjunctive Pharmacotherapy and Coronary Intervention. In Ever D Grech; David R Ramsdale, ed. Practical INterventional Cardiology. 2 ed. UK: Martin Dunitz, pp. 0-0.
  • Chew, D., Szczech, L., Coladonato, J. and Reddan, D. (2002). The Heart and the Renal System. In Eric J Topol, ed. Textbook of Cardiovascular Medicine. NA: Lippincott Williams and Wilkins, pp. 797-814.
    [Web Link]
  • Chew, D. and Horrigan, M. (2001). Catheter-based Reperfusion for Acute Myocardial Infarction. In John Boland, David Muller, ed. Cardiology and Cardiac Catheterisation: the essential guide. Netherlands: Harwood Academic Publishers, pp. 231-243.
    [10.1201/b14736-21] [Web Link]
  • Chew, D. and Topol, E. (2001). Stents: Indications and Limitations. In Eric J Topol, ed. Textbook of Interventional Cardiology. Unknown: Saunders, pp. 0-0.
    [Web Link]
  • Chong, F., Malkin, C., Penhall, A., Selvanayagam, J., Chew, D., Joseph, M., et al. (2011). Percutaneous Balloon Aortic Valvuloplasty for Severe Aortic Stenosis: Haemodynamic Evaluation by Echocardiography. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Perth, Australia. Aug 2011, pp. S186-S186.
    [10.1016/j.hlc.2011.05.461]
  • Costa, B., Ranasinghe, I., Turnbull, F., Antonis, P., Coverdale, S., Brown, A., et al. (2011). Emerging Practice Patterns in the Management of STEMI and High Risk ACS-early Findings from the CONCORDANCE Registry. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Perth, Australia. Aug 2011, pp. S33-S33.
    [10.1016/j.hlc.2011.05.083]
  • Wong, Y., Joseph, M., Chew, D., Bennetts, J., Chong, F., Selvanayagam, J., et al. (2011). Comparison of Early Haemodynamic Performance Between Transcatheter Aortic Valve Implantation (TAVI) and Surgical Aortic Valve Replacement (SAVR) Bioprosthesis. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Perth, Australia. Aug 2011, pp. S164-S165.
    [10.1016/j.hlc.2011.05.409]
  • Walters, D., Sinhal, A., Barron, D., Pasupati, S., Thambar, S., Yong, G., et al. (2011). Australian and New Zealand Source Registry: Edwards Sapien Transcatheter Aortic Valve Replacement - Day Outcomes. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Perth, Australia. Aug 2011, pp. S116-S116.
    [10.1016/j.hlc.2011.05.289]
  • Waddell-Smith, K., Parsonage, W., Arstall, M., Coverdale, S., Prasad, D., Cross, D., et al. (2011). Under-treatment of women with acute coronary syndrome appears to be related to unrecognised risk. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Perth, Australia, pp. S44-S44.
    [10.1016/j.hlc.2011.05.111]
  • Ranasinghe, I., Freedman, B., Neubeck, L., Aliprandi-Costa, B., Devlin, G., Lefkovits, J., et al. (2011). Temporal Change in Pre-hospital Statin Use and Total Cholesterol Levels in Patients Presenting with Acute Coronary Syndromes. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Elsevier. Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand. Perth, Australia. Aug 2011, pp. S56-S56.
    [10.1016/j.hlc.2011.05.142]
  • Prakash, R., Malkin, C., Chew, D., Horsfall, M., Amerena, J., Markwick, A., et al. (2011). The Impact of Advanced Age on Clinical Outcome from an Early Invasive Strategy in Patients with Acute Coronary Syndrome. The Acute Coronary Syndrome Prospective Audit registry (ACACIA) In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Perth, Australia. Aug 2011, pp. S149-S149.
    [Web Link]
  • Prakash, R., Chew, D., Sinhal, A., Horsfall, M., Green, C., Makoy, D., et al. (2011). Expected Survival and Value of Transcatheter Aortic Valve Implantation (TAVI) Versus Medical Therapy in Patients with Severe Aortic Stenosis (AS) Based on the Flinders Medical Centre (FMC) Comparative Dataset. In Abstracts for the Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, Annual Scientific Meeting. Elsevier. Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research, Australasian Section, A
  • Perry, R., Patil, S., Horsfall, M., Marx, C., Chew, D.P., Joseph, M., et al. (2018). Global Strain and Mechanical Dispersion Improves Risk Stratification of Malignant Ventricular Arrhythmias and Major Adverse Cardiac Events over Ejection Fraction Alone. Journal of The American College of Cardiology, 71(11) pp. 1663.
    [10.1016/S0735-1097(18)32204-6]
  • Astley, C., Ranasinghe, I., Brieger, D., Ellis, C., Redfern, J., Briffa, T., et al. (2017). Expertise and infrastructure capacity impacts acute coronary syndrome outcomes. Australian Health Review, April 20
  • French, J.K., Chew, D.P. and Aylward, P.E. (2017). Pre-hospital thrombolysis in ST-segment elevation myocardial infarction: a regional Australian experience. MJA Medical Journal of Australia, 8 pp. 369-369.
  • Iyngkaran, P., Liew, D., McDonald, P., Thomas, M., Reid, C., Chew, D.P., et al. (2016). Phase 4 Studies in Heart Failure - What is Done and What is Needed? Current Cardiology Reviews, 12(3) pp. 216-230.
  • Chew, D.P. and Briffa, T. (2015). The clinical care standards in ACS: towards an integrated approach to evidence translation in ACS care. Heart Lung Circulation, 24(3) pp. 213-215.
  • French, J.K., Burgess, S. and Chew, D.P. (2015). Re-infarction after primary percutaneous coronary intervention. Current Opinion in Cardiology, 30(4) pp. 354-358.
  • Ganesan, A.N., Chew, D.P., Hartshorne, T., Selvanayagam, J.B., Aylward, P.E., Sanders, P., et al. (2015). The Impact of Atrial Fibrillation Type on the Risk of Thromboembolism, Mortality and Bleeding: A Systematic Review and Meta-analysis. Circulation, 132(3)
  • Pathik, M.B., De Pasquale, C.G., McGavigan, A.D., Sinhal, S.R., Vaile, J.C., Tideman, P.A., et al. (2015). Sub-specialization in cardiology care and outcome: should clinical services be redesigned, again? European Heart Journal, 36(S1) pp. 630.
  • Chew, D.P. and Cullen, L. (2014). The promise of high-sensitivity troponin testing. Medical Journal of Australia, 3 pp. 125-126.
  • Chew, D. (2012). National heart foundation response to letter, "ambiguous cardiac troponin recommendations" Heart, Lung and Circulation, 21(3) pp. 198.
    [10.1016/j.hlc.2011.12.001] [Scopus]
  • Lee, L. and Chew, D. (2012). Promise of factor Xa inhibition in acute coronary syndromes. Current Cardiology Reports, 14(1) pp. 40-48.
    [10.1007/s11886-011-0228-8] [Scopus]
  • Joseph, M., R, P., Sinhal, A., Chew, D., Carlson, S. and Webb, J. (2011). Acute mitral regurgitation complicating transcatheter aortic valve implantation. JOURNAL OF HEART VALVE DISEASE, 20(3) pp. 361-363.
    [Scopus] [Web Link]
  • Urban, P., Abizaid, A., Banning, A., Bartorelli, A., Baux, A., Dzavik, V., et al. (2011). Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry. Journal of The American College of Cardiology, 57(13) pp. 1445-1454.
    [10.1016/j.jacc.2010.11.028] [Scopus]
  • Brieger, D., Aroney, C., Chew, D., Kelly, A.M., Walters, D., Toohey, C., et al. (2010). Acute coronary syndromes: consensus recommendations for translating knowledge into action. MJA Medical Journal of Australia, 192(12) pp. 700-701.
    [Scopus] [Web Link]
  • Serebruany, V., Floyd, J. and Chew, D. (2010). Excess of Solid Cancers After Prasugrel: The Food and Drug Administration Outlook. American Journal of Therapeutics,
    [10.1097/MJT.0b013e3181e9b675] [Scopus]
  • Clark, R., Wilkinson, D., Coffee, N., Eckert, K., Astles, P., Milligan, M., et al. (2009). Mapping services to support a patient's journey through evidence-based care pathways after a cardiac event. Heart, Lung and Circulation, 18(3) pp. 266-266.
    [10.1016/j.hlc.2009.05.656] [Web Link]
  • Wallentin, L., Becker, R., Budaj, A., Cannon, C., Emanuelsson, H., Held, C., et al. (2009). Ticagrelor versus clopidogrel in patients with acute coronary syndromes. New England Journal of Medicine, 361(11) pp. 1045-1057.
    [10.1056/NEJMoa0904327] [Scopus]
  • Sinhal, A.R. and Chew, D.P. (2008). Percutaneous coronary intervention for acute coronary syndromes in Australia. Indian Heart Journal, 60(6) pp. 637-641.
    [Scopus]
  • Chew, D.P. (2005). Cost-effectiveness of drug-eluting stents: if only all things were equal. Medical Journal of Australia, 182(8) pp. 376-377.
    [Scopus] [Web Link] [Web Link]
  • Astley, C., Molloy, D.A., Kangarahan, N., Aylward, P.E., Vaile, J. and Chew, D.P. (2005). Incremental Cost of Invasive Management In the Australian Setting. Heart, Lung and Circulation, 14 pp. 211-211.
  • Sabatine, M.S., Cannon, C.P., Gibson, C.M., López-Sendón, J.L., Montalescot, G., Theroux, P., et al. (2005). Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. New England Journal of Medicine, 352(12) pp. 1179-1189.
    [10.1056/NEJMoa050522] [Scopus] [Web Link] [Web Link]
  • Chiu, J., Bhatt, D.L., Chew, D.P., Whitlow, P.L., Lincoff, A.M., Ellis, S.G., et al. (2004). Impact of female sex on outcome after percutaneous coronary intervention. American Heart Journal, 148(6) pp. 998-1002.
    [10.1016/j.ahj.2004.05.045]
  • White, H. and Chew, D. (2002). Bivalirudin, a thrombin-specific anticoagulant for unstable angina and coronary interventions. Drugs,
  • Bhatt, D., Kapadia, S., Chew, D., Mukherjee, D., Ziada, K., Topol, E., et al. (2001). Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting. European Heart Journal, 322 pp. 634-634.
    [Web Link]
  • Bhatt, D., Mukherjee, D., Roffi, M., Kapadia, S., Ziada, K., Chew, D., et al. (2001). Is Simultaneous Bilateral Carotid Artery Stenting Safe? Journal of The American College of Cardiology, 37(2)
  • Chan, A., Bhatt, D., Chew, D., Quinn, M., Moliterno, D., Topol, E., et al. (2001). Stunning mortality benefit of HMG-CoA reductase inhibitors beginning early after percutaneous coronary intervention - results from 6,412 patients. Canadian Journal of Cardiology, 17 pp. 177C-177C.
  • Chan, A., Chew, D., Bhatt, D., Moliterno, D., Topol, E. and Ellis, S. (2001). Sustained mortality benefit for cardiogenic shock complicating acute MI - Experience from an 8-year registry. Canadian Journal of Cardiology, 17 pp. 213C-213C.
  • Chan, A., Quinn, M., Bhatt, D., Chew, D., Topol, E. and Ellis, S. (2001). Striking mortality benefit of b-blocker within the first year after elective PCI - Results from 6,006 patients. Canadian Journal of Cardiology, 17 pp. 177C-177C.
  • Bhatt, D., Chew, D., Robbins, M., Roffi, M., Cho, L., Yadav, J., et al. (2001). Elevated Baseline CRP Levels Predict Death or MI in Diabetic Patients Undergoing Percutaneous Coronary Intervention. Journal of The American College of Cardiology, 37(2)
  • Bhatt, D., Chew, D., Hirsch, A., Ringleb, P., Hacke, W. and Topol, E. (2001). Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery. Circulation, 104 pp. e76.
  • Chew, D., Robbins, M., Bhatt, D., Mukherjee, D., Roffi, M., Topol, E., et al. (2001). CRP provides prognostic value in addition to ACC/AHA lesion score following PCI. Journal of The American College of Cardiology, 37(2)
  • Roffi, M., Mukherjee, D., Bhatt, D., Chew, D., Ziada, K., Prosper, D., et al. (2001). Percutaneous coronary interventions of coronary bypass grafts have doubled major adverse events. Journal of The American College of Cardiology, 37(2)
  • Roffi, M., Chew, D., Mukherjee, D., Bhatt, D., Robbins, M. and Topol, E. (2001). Glycoprotein IIb/IIIa inhibitors in the medical management of unstable ischemic syndromes without persistent ST-segment elevation: a meta-analysis of the randomized trials. Journal of The American College of Cardiology, 37(2)
  • Cho, L., Ellis, S., Chew, D., Topol, E. and Penn, M. (2001). Patient Rather Than Lesion Specific Predisposition for Restenosis. Journal of The American College of Cardiology, 37(2)
  • Jeremias, A., Albirini, A., Ziada, K., Chew, D., Roffi, M., Schoenhagen, P., et al. (2001). Creatine Kinase-MB Elevation After Percutaneous Coronary Intervention is a Predictor of Long-Term Mortality in Patients With Renal Dysfunction. Journal of The American College of Cardiology, 37(2)
  • Jeremias, A., Bhatt, D., Chew, D., Ziada, K., Albirini, A., Brener, S., et al. (2001). Glycoprotein IIb-IIIa Inhibition With Abciximab During Percutaneous Coronary Intervention In Patients With Chronic Renal Insufficiency. American Journal of Cardiology, 88
  • Robbins, M., Chew, D., Bhatt, D., Albirini, A., Cho, L., Schneider, J., et al. (2001). Striking Prognostic Significance of elevated CRP in Renal Impairment patients undergoing PCI. Journal of The American College of Cardiology, 37(2)
  • Roffi, M., Chan, A., Chew, D., Robbins, M., Mukherjee, D., Bhatt, D., et al. (2001). Stents and glycoprotein IIb/IIIa inhibitors do not improve 30-day outcome in bypass graft percutaneous interventions: a retrospective registry-based analysis. Journal of The American College of Cardiology, 37(2)
  • Chew, D. and Ellis, S. (2000). Cardiogenic Shock: an Editorial. Evidence-based Cardiovascular Medicine,
  • Chew, D. and Topol, E. (2000). Glycoprotein IIb/IIIa Inhibition and Post-operative Acute Myocardial Infarction: A case report. Journal of Invasive Cardiology,
  • Roffi, M., Chew, D., Ziada, K. and Whitlow, P. (2000). Percutaneous Coronary Intervention of Unprotected Left Main Coronary Stenosis. Cardiovascular Medicine, 3 pp. 324-326.
  • Bing, R., Goodmena, S.G., Yan, A.T., Fox, K., Gale, C.P., Hyun, K., et al. (2018). Use of clinical risk stratification in non-ST elevation acute coronary syndromes: an analysis from the CONCORDANCE registry. European Heart Journal: Quality of CAre & Clinical Outcomes,
  • Zheng, W., Zheng, W., Wang, J., Xu, F., Zheng, J., Ma, J., et al. (2018). Evaluation and management of patients with acute chest pain in China (EMPACT): protocol for a prospective, multicentre registry study. BMJ Open, 8(1) pp. e017872-e017872.
  • Chow, C.K., Thiagalingam, A., Santo, K., Kok, C., Thakkar, J., Stepien, S., et al. (2018). TEXT messages to improve MEDication adherence and Secondary prevention (TEXTMEDS) after acute coronary syndrome: a randomised clinical trial protocol. BMJ Open, 8(1) pp. e019463-e019463.
  • Anastasius, M., Lau, J.K., Hyun, K.K., D'Souza, M., Patel, A., Rankin, J., et al. (2017). The underutilisation of dual antiplatelet therapy in acute coronary syndrome. International Journal of Cardiology, 240 pp. 30-36.
  • Brooks, M., Ellis, C., Gamble, G., Devlin, G., Elliott, J., Hammett, C., et al. (2017). A Comparison of Radial and Femoral Coronary Angiography in Patients From SNAPSHOT ACS, a Prospective Acute Coronary Syndrome Audit in Australia and New Zealand. Heart Lung Circulation, 26(3) pp. 258-267.
  • Chew, D.P. and Bhatt, D.L. (2017). Predicting Risk in ACS: Taking the Long-Term View. Journal of The American College of Cardiology, 70(15) pp. 1858-1860.
  • Chew, D.P., Scott, I.A., Cullen, L., French, J.K., Briffa, T., Tideman, P., et al. (2017). Corrigendum to 'National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016' Heart Lung and Circulation volume 25, (2016) 898 - 952. Heart Lung Circulation, 26(10) pp. 1117-1117.
  • Halabi, A., Chew, D.P., Horsfall, M., Huyn, K., MacIsaac, A., Juergens, C., et al. (2017). Has invasive management for acute coronary syndromes become more 'risk-appropriate': pooled results of five Australian registries. European Heart Journal: Quality of CAre & Clinical Outcomes, 3(2) pp. 133-140.
  • Hancock, D.G., Chuang, M.Y., Bystrom, B., Halabi, A., Jones, R., Horsfall, M., et al. (2017). Rational clinical evaluation of suspected acute coronary syndromes: The value of more information. Emergency Medicine Australasia, 29(6) pp. 664-671.
  • Scott, I.A., Chew, D.P. and Branagan, M. (2017). Raising the bar on guideline utility and trustworthiness. Internal Medicine Journal, 47(6) pp. 613-616.
  • Hyun, K.K., Redfern, J., Woodward, M., D'Souza, M., Shetty, P., Chew, D.P., et al. (2017). Socioeconomic Equity in the Receipt of In-Hospital Care and Outcomes in Australian Acute Coronary Syndrome Patients: The CONCORDANCE Registry. Heart Lung Circulation, 20 pp. S1443-9506.
  • Kaambwa, B.C., Ratcliffe, J., Horsfall, M., Astley, C., Karnon, J., Coates, P., et al. (2017). Cost effectiveness of high-sensitivity troponin compared to conventional troponin among patients presenting with undifferentiated chest pain: A trial based analysis. International Journal of Cardiology, 238 pp. 144-150.
  • O'Shea, C., McGavigan, A.D., Clark, R.A., Chew, D.P. and Ganesan, A.N. (2017). Mobile health: an emerging technology with implications for global internal medicine. Internal Medicine Journal, 47(6) pp. 616-619.
    [10.1111/imj.13440] [Scopus]
  • Papendick, C., Blyth, A., Seshadri, A., Edmonds, M.J., Briffa, T., Cullen, L., et al. (2017). A randomized trial of a 1-hour troponin T protocol in suspected acute coronary syndromes: Design of the Rapid Assessment of Possible ACS In the emergency Department with high sensitivity Troponin T (RAPID-TnT) study. American Heart Journal, 190 pp. 25-33.
  • Partington, A., Chew, D.P., Ben-Tovim, D.I., Horsfall, M., Hakendorf, P.H. and Karnon, J. (2017). Screening for important unwarranted variation in clinical practice: a triple-test of processes of care, costs and patient outcomes. Australian Health Review, 41(1) pp. 104-110.
  • Hyun, K.K., Redfern, J., Woodward, M., Briffa, T.G., Chew, D.P., Ellis, C., et al. (2017). Is There Inequity in Hospital Care Among Patients With Acute Coronary Syndrome Who Are Proficient and Not Proficient in English Language?: Analysis of the SNAPSHOT ACS Study. Journal of Cardiovascular Nursing, 32(3) pp. 288-295.
    [10.1097/JCN.0000000000000342] [Scopus]
  • Brieger, D., Hyun, K.K., Chew, D.P., Amerena, J., Farouque, H., MacIsaac, A., et al. (2016). The relationship between the proportion of admitted high risk ACS patients and hospital delivery of evidence based care. International Journal of Cardiology, 222 pp. 86-92.
  • Swan, A., Prakash, R., Chew, D.P., Perry, R., Sinhal, A.R., Selvanayagam, J.B., et al. (2016). Instantaneous Decrease in Left Ventricular Afterload during Transcatheter Aortic Valve Implantation Results in Immediate Changes in Left Ventricular Strain. Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 33(5) pp. 742-748.
    [10.1111/echo.13153] [Scopus]
  • Chan, T., Dabin, B., Hyun, K.K., Ranasinghe, I., Neubeck, L., Aliprandi-Costa, B., et al. (2016). Falling cholesterol trend at acute coronary syndrome presentation is strongly related to statin use for secondary prevention. International Journal of Cardiology, 212 pp. 192-197.
  • Chan, W., Goodman, S., Brieger, D., Fox, K.A., Gale, C.P., Chew, D.P., et al. (2016). Clinical Characteristics, Management, and Outcomes of Acute Coronary Syndrome in Patients With Right Bundle Branch Block on Presentation. American Journal of Cardiology, 117(5) pp. 754-759.
  • Chew, D.P., Herkes, R. and Page, M.A. (2016). Clinical care standards: appropriate care everywhere - acute coronary syndromes as an example. Medical Journal of Australia, 205(10) pp. 8-11.
  • Chew, D.P., Horsfall, M., McGavigan, A.D., Tideman, P.A., Vaile, J.C., O'Shea, C., et al. (2016). Condition-specific Streaming versus an Acuity-based Model of Cardiovascular Care: A Historically-controlled Quality Improvement Study Evaluating the Association with Early Clinical Events. Heart Lung Circulation, 25(1) pp. 19-28.
  • Chew, D.P., MacIsaac, A., Lefkovits, J., Harper, R.W., Slawomirski, L., Braddock, D., et al. (2016). Variation in coronary angiography rates in Austratia: correlations with socio-dernograp health service and disease burden indices. Medical Journal of Australia, 205(3) pp. 114-120.
    [10.5694/mja15.01410] [Scopus]
  • Chew, D.P., Scott, I.A., Cullen, L., French, J.K., Briffa, T., Tideman, P.A., et al. (2016). National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the management of acute coronary syndromes 2016. Medical Journal of Australia, 205(3) pp. 128-133.
  • Chew, D.P., Scott, I.A., Cullen, L., French, J.K., Briffa, T.G., Tideman, P.A., et al. (2016). National Heart Foundation of Australia & Cardiac Society of Australia and New Zealand: Australian Clinical Guidelines for the Management of Acute Coronary Syndromes 2016. Heart, Lung and Circulation, 25(9) pp. 895-951.
    [10.1016/j.hlc.2016.06.789] [Scopus]
  • Chew, D.P., Zeitz, C.J., Worthley, M.I., Grantham, H.J., Beltrame, J.F., Arstall, M.A., et al. (2016). Randomized Comparison of High-Sensitivity Troponin Reporting in Undifferentiated Chest Pain Assessment. Circulation: Cardiovascular Quality and Outcomes, 9(5) pp. 542-553.
    [10.1161/CIRCOUTCOMES.115.002488] [Scopus]
  • Chuang, A., Hancock, D.G., Horsfall, M., Alhammad, N.J., Zhou, J., Cullen, L., et al. (2016). The predictive value of high sensitivity-troponin velocity within the first 6 h of presentation for cardiac outcomes regardless of acute coronary syndrome diagnosis. International Journal of Cardiology, 204 pp. 106-111.
    [10.1016/j.ijcard.2015.11.132] [Scopus]
  • Farshid, A., Brieger, D., Hyun, K.K., Hammett, C.J., Ellis, C., Rankin, J., et al. (2016). Characteristics and Clinical Course of STEMI Patients who Received no Reperfusion in the Australia and New Zealand SNAPSHOT ACS Registry. Heart Lung Circulation, 25(2) pp. 132-139.
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  • White, H.D., Chew, D.P., Hoekstra, J., Miller, C.D., Pollack, C.V., Feit, F., et al. (2008). Safety and efficacy of switching from either unfractionated Heparin or Enoxaparin to Bivalirudin in patients with Non-ST-Segment elevation acute coronary syndromes managed with an invasive strategy. Results from the ACUITY trial. Journal of The American College of Cardiology, 51(18) pp. 1734-1741.
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  • Perry, R., De Pasquale, C.G., Chew, D.P., Aylward, P.E. and Joseph, M. (2006). QRS duration alone misses cardiac dyssynchrony in a substantial proportion of patients with chronic heath failure. Journal of The American Society of Echocardiography, 19(10) pp. 1257-1263.
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  • Chen, M.S., Bhatt, D.L., Chew, D.P., Moliterno, D.J., Ellis, S.G. and Topol, E.J. (2005). Outcomes in African Americans and whites after percutaneous coronary intervention. American Journal of Medicine, 118(9) pp. 1019-1025.
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  • De Pasquale, C.G., Arnolda, L.F., Aylward, P.E., Chew, D.P. and Bersten, A.D. (2004). Plasma surfactant protein-B: a novel biomarker in chronic heart failure. Circulation, 110(9) pp. 1091-1096.
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  • Koster, A., Chew, D.P., Merkle, F., Gruendel, M., Jurmann, M., Kuppe, H., et al. (2004). Extracorporeal elimination of large concentrations of tirofiban by zero-balanced ultrafiltration during cardiopulmonary bypass; an in vitro investigation. Anesthesia and Analgesia, 99(4) pp. 989-992.
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  • Yen, M.H., Bhatt, D.L., Chew, D.P., Harrington, R.A., Newby, L.K., Ardissino, D., et al. (2003). Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromes. American Journal of Medicine, 115(4) pp. 318-321.
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  • Koster, A., Chew, D.P., Kuebler, W., Habazetti, H., Hetzer, R. and Kuppe, H. (2003). High antithrombin III levels attentuate hemostatic activation and leukocyte activation during cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery, 126(3) pp. 906-907.
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  • Bhatt, D.L., Chew, D.P., Lincoff, A.M., Simoons, M.L., Harrington, R.A., Ommen, S.R., et al. (2003). Effect of revascularization on mortality associated with an elevated white blood cell count in acute coronary syndromes. American Journal of Cardiology, 92(2) pp. 136-140.
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  • Jeremias, A., Bhatt, D., Chew, D., Ziada, K., Albirini, A., Brener, S., et al. (2002). Safety of abciximab during percutaneous coronary intervention in patients with chronic renal insufficiency. American Journal of Cardiology, 89(10) pp. 1209-1211.
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  • Ellis, S., Chew, D., Chan, A., Whitlow, P., Schneider, J. and Topol, E. (2002). Death following creatine kinase-MB elevation after coronary intervention: identification of an early risk period: importance of creatine kinase-MB level, completeness of revascularization, ventricular function, and probable benefit of statin therapy. Circulation, 106(10) pp. 1205-1210.
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  • Chew, D., Moliterno, D. and Herrmann, H. (2002). Present and Potential Future Paradigms for the Treatment of ST-Segment Elevation Acute Myocardial Infarction. Journal of Invasive Cardiology, 14(2)
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  • Chew, D. and Moliterno, D. (2002). Managing Unstable Angina in High-Risk Patients. Journal of Invasive Cardiology, 14(Suppl) pp. 31A-48A.
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  • Chew, D. and Bhatt, D. (2002). Optimizing Glycoprotein IIb/IIIa inhibition: lessons from recent randomized controlled trials. Internal Medicine Journal, 32(7) pp. 338-345.
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  • Chan, A., Quinn, M., Bhatt, D., Chew, D., Moliterno, D., Topol, E., et al. (2002). Mortality benefit of beta-blockade after successful elective percutaneous coronary intervention. Journal of The American College of Cardiology, 40(4) pp. 669-675.
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  • Chan, A., Bhatt, D., Chew, D., Quinn, M., Moliterno, D., Topol, E., et al. (2002). Early and Sustained Survival Benefit associated with Statin therapy at the time of Percutaneous Coronary Intervention. Circulation, 105 pp. 691-696.
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  • Reginelli, J. and Chew, D. (2002). Direct Thrombin Inhibitors for Percutaneous Coronary Intervention in the Current Era of Platelet Glycoprotein IIbDIIa Inhibition. Journal of Interventional Cardiology, 15(2) pp. 141-146.
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  • Tamberella, M., Bhatt, D., Chew, D., Kereiakes, D., Topol, E. and Steinhubl, S. (2002). Relation of Platelet Inactivation with Intravenous Glycoprotein IIb/IIIa Antagonists To Major Bleeding: (from the GOLD Study) American Journal of Cardiology, 89(12) pp. 1429-1431.
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  • Bhatt, D., Chew, D. and Topol, E. (2001). The importance of intravenous antiplatelet therapy with abciximab during percutaneous coronary intervention in diabetic patients. Cardiovascular Reviews and Reports, 22(3) pp. 161-164.
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  • Bhatt, D., Chew, D., Hirsch, A., Ringleb, P., Hacke, W. and Topol, E. (2001). Superiority Of Clopidogrel Versus Aspirin In Patients With Prior Cardiac Surgery. Circulation, 103(3) pp. 363-368.
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  • Bhatt, D., Kapadia, S., Chew, D., Ziada, K., Mukherjee, D., Roffi, M., et al. (2001). Dual antiplatelet therapy with clopidogrel and aspirin after carotid stenting. Journal of Invasive Cardiology, 13(12) pp. 767-771.
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  • Chan, A., Chew, D. and Lincoff, A. (2001). Update on Pharmacology for Restenosis. Current Interventional Cardiology Reports, 3(2) pp. 149-155.
  • Chew, D. and Bhatt, D. (2001). Oral glycoprotein IIb/IIIa antagonists in coronary artery disease. Current Cardiology Reports, 3(1) pp. 63-71.
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  • Chew, D. and Moliterno, D. (2001). GP IIb/IIIa inhibitors in coronary artery disease management: what the latest trials tell us. CLEVELAND CLINIC JOURNAL OF MEDICINE, 68(12) pp. 1017-1023.
    [Scopus]
  • Chew, D., Bhatt, D. and Topol, E. (2001). Oral glycoprotein IIb/IIIa inhibitors: why don't they work? American Journal of Cardiovascular Drugs, 1(6) pp. 421-428.
    [Scopus]
  • Chew, D., Bhatt, D., Lincoff, A., Moliterno, D., Brener, S., Wolski, K., et al. (2001). Defining the Optimal Activated Clotting Time During Percutaneous Coronary Intervention: Aggregate Results From 6 Randomized, Controlled Trials. Circulation, 103 pp. 961-966.
    [Scopus] [Web Link]
  • Chew, D., Bhatt, D., Robbins, M., Mukherjee, D., Roffi, M., Schneider, J., et al. (2001). Effect of clopidogrel added to aspirin before percutaneous coronary intervention on the risk associated with C-reactive protein. American Journal of Cardiology, 88(6) pp. 672-674.
    [Scopus]
  • Chew, D., Bhatt, D., Robbins, M., Penn, M., Schneider, J., Lauer, M., et al. (2001). Incremental Prognostic Value of Elevated Baseline C-reactive Protein among Established Markers of Risk in Percutaneous Coronary Intervention. Circulation, 104(9) pp. 992-997.
    [Scopus]
  • Chew, D., Bhatt, D., Sapp, S. and Topol, E. (2001). Increased Mortality with Oral Platelet Glycoprotein IIb/IIIa Antagonists: A Meta-analysis of Phase III Multicenter Randomized Trials. Circulation, 103(2) pp. 201-206.
    [Scopus]
  • Roffi, M., Chew, D., Mukherjee, D., Bhatt, D., White, J., Heeschen, C., et al. (2001). Platelet Glycoprotein IIb/IIIa Inhibitors Reduce Mortality in Diabetic Patients with Non-ST-Segment-Elevation Acute Coronary Syndromes. Circulation, 104(23) pp. 2767-2771.
    [Scopus]
  • Mukherjee, D., Chew, D., Robbins, M., Yadav, J., Raymond, R. and Moliterno, D. (2001). Clinical application of procedural platelet monitoring during percutaneous coronary intervention among patients at increased bleeding risk. Journal of Thrombosis and Thrombolysis, 11(2) pp. 151-154.
    [Scopus]
  • Chew, D. and Moliterno, D. (2000). A critical appraisal of platelet glycoprotein IIb/IIIa inhibition. Journal of The American College of Cardiology, 36(7) pp. 2028-2035.
    [10.1016/S0735-1097(00)00979-7] [Scopus] [Web Link]
  • Tonkin, A. and Chew, D. (1999). How Can We Stratify Patients With Unstable Angina And Determine Optimal Therapy? Dialogues in Cardiovascular Medicine, 4(3) pp. 146-158.
    [Web Link] [Web Link]
  • Chew, D. (2011). Anticoagulation in Percutaneous Coronary Intervention. In EJ Topol, PS Teirstein, ed. Textbook of Interventional Cardiology. 6th ed. USA: Saunders, pp. 113-125.
    [Web Link]
  • Chew, D. and Huynh, L. (2011). Applying evidence based medicine, guidelines and clinical pathways in the Coronary Care Unit. In Peter L Thompson, ed. Coronary Care Manual, 2nd Edition. 2nd ed. Chatswood, New South Wales: Elsevier Australia, pp. 12-18.
    [Web Link]
  • Chew, D. (2008). Anticoagulation in PCI. In Eric J Topol, ed. Textbook of Interventional Cardiology 5th Edition. USA: Saunders Elsevier, pp. 165-182.
    [Web Link]
  • Lehman, S., Chew, D.P. and White, H.D. (2008). Glycoprotein IIb/IIIa Inhibitors. In Deepak L Bhatt, ed. Platelets in Cardiovascular Disease. London: Imperial College Press, pp. 65-86.
  • Chew, D., Lehman, S. and White, H. (2007). Direct Thrombin inhibition in Percutaneous Coronary Intervention. In Nicholas N Kipshidze, Jawed Fareed, Jeffrey W. Moses, Patrick W Serruys and Cathy Kennedy, ed. Textbook of Interventional Cardiovascular Pharmacology. UK: CRC Press, pp. 85-92.
    [Web Link]
  • Chew, D. (2006). Platelets, Anti-platelet therapy and Inflammation. In Ridker & Rafai, ed. CRP: Atherothrombosis and Cardiovascular risk. NA: NA.
  • Chew, D. and White, H. (2004). Pathophysiology, Classification and Clinical Features of ACS. In Deepak L Bhatt & Marcus D Flather, ed. Handbook of Acute Coronary Syndromes. United Kingdom: Remedica Publishing, pp. 1-22.
    [Web Link]
  • Chew, D. (2002). Anti-thrombin Therapy in Percutaneous Coronary Intervention. In NA, ed. The Year in Interventional Cardiology. UK: CRC Press, pp. 30-38.
    [Web Link]
  • Chew, D. and Lincoff, A. (2002). Adjunctive Pharmacotherapy and Coronary Intervention. In Ever D Grech; David R Ramsdale, ed. Practical INterventional Cardiology. 2 ed. UK: Martin Dunitz, pp. 0-0.
  • Chew, D., Szczech, L., Coladonato, J. and Reddan, D. (2002). The Heart and the Renal System. In Eric J Topol, ed. Textbook of Cardiovascular Medicine. NA: Lippincott Williams and Wilkins, pp. 797-814.
    [Web Link]

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