Position/s

AM, Professor of Global Gastrointestinal Health
Faculty of Medicine, Nursing and Health Sciences

Biography

Graeme Young underwent secondary education at Northcote High School Melbourne and subsequently graduated MB, BS in 1969 from the University of Melbourne. After attaining Fellowship of the Royal Australasian College of Physicians (1978), he studied overseas on a Fogarty International Fellowship (NIH) and RACP Travelling Scholarship at Washington University, St Louis. He graduated MD in 1981 (University of Melbourne, research), and in 1997 was appointed as the foundation Professor of Gastroenterology at Flinders University of South Australia, and Regional Head of Gastroenterology and Hepatology, Southern Adelaide Health Service. In 2002, Graeme was additionally appointed as Director of Development, Flinders Centre for Innovation in Cancer. In 2005, he became Head of the Flinders Cancer Control Alliance, subsequently the Flinders Centre for Cancer Prevention and Control (FCCPC) and now Flinders Centre for Innovation in Cancer (FCIC). In 2011,he became Professor of Global Gastrointestinal Health at Flinders University while relinquishing his clinical appointments.

Qualifications

MB BS, Melbourne 1969
MD, Melbourne (by research thesis) 1981
FRACP, 1978
FTSE, Fellow, Australian Academy of Technological Sciences and Engineering, 2008
AGAF, Fellow, American Gastroenterological Association, 2009

Honours, awards and grants

In 2014, he was made a Member of the Order of Australia (AM)  for significant service to medicine.
In 2013, he received the South Australian Scientist of the Year Award.
In 2011, he was awarded the title of Mathew Flinders Distinguished Professor from Flinders University.
In 2009, Graeme was awarded the Distinguished Research Prize of the Gastroenterological Society of Australia at its 50th Anniversary Celebrations in Sydney. Also, he was elected a Fellow of the American Gastroenterological Association (AGAF).
In 2008, Graeme was elected as a Fellow of the Australian Academy of Technological Sciences and Engineering (AATSE).
In 2007, Graeme was awarded South Australian of the Year in Health for his screening research and the role he played in the establishment of the National Bowel Cancer Screening Program. Also in 2007, he was recognised as one of the fifty most influential people in South Australia.
In 2006, he received a 'Ten of the Best' award from the National Health and Medical Research Council of Australia for his research into screening for colorectal cancer.
Graeme was appointed as CSIRO P-Health Flagship Fellow in 2005, and in 2009 he was awarded Adjunct Professor, Department of Gastrointestinal Sciences, Christian Medical College, Vellore India.

Key responsibilities

Professor of Global GI Health - leader of the research teams (molecular biology, cell biology, population screening, nutrition)
Chairman of the Governing Council (board) of the FCIC

2012-2013 Consultant, Zinc Panel, NICHD funded BOND (Biomarkers of Nutrition for Development) initiative.

2012-ongoing Chairman of the Governing Council (board) of the Flinders Centre for Innovation in Cancer

2005-2013     Chairman, Colorectal Cancer Screening Committee, World Endoscopy Organization (WEO)

Teaching interests

Graeme's teaching interests focus mainly on prevention of colorectal cancer but spread more broadly to cover most of gastrointestinal sciences. He is experienced in education across most branches of health care professionals and students, although his major focus would be to Gastroenterologists, health service providers in public health and cancer prevention including screening, and scientists working in fields related to bowel health.

Research expertise

  • Clinical sciences
  • Nutrition and dietetics
  • Oncology and carcinogenesis

Research interests

He has an international reputation, especially in the broad field of colorectal cancer and its prevention and colorectal epithelial biology. He has many publications including articles on intestinal cell biology, mechanisms of dietary prevention, screening and surveillance for colorectal cancer, dietary impact on colorectal disease, colonic fermentation of dietary substances and public health issues related to bowel health and bowel cancer. He is the senior editor on several comprehensive textbooks and contributes chapters to major textbooks on gastrointestinal medicine.

He currently heads a large research initiative at the Flinders Centre for Innovation in Cancer. He has several teams of research personnel covering population screening, clinical research, epithelial biology and molecular biology. He has attracted funding from Australian and overseas bodies, including NHMRC, Cancer Councils, NIH, industry, Australian Cancer Research Fund, Bill and Melinda Gates Foundation, NGOs and government.

Supervisory interests

  • Colorectal cancer screening
  • Control of diarrhoea and malnutrition
  • Diet and oncogenesis
  • Zinc nutrition

RHD research supervision

Completion

Principal supervisor : Gastroenterology (20) ; Gastroenterology (20) ;

RHD Student Achievements

  • Jean Winter
    University medal - December 2012

Publications

  • Young, G.P., Macrae, F.A. and Thomas, A.C. (2009). Neoplastic and non-neoplastic polyps of the colon and rectum. In Yamada, Tadataka, ed. Atlas of Gastroenterology. 4 ed. USA: Wiley-Blackwell, pp. 423-448.
  • Macrae, F.A., Young, G.P. and Thomas, A.C. (2008). Colorectal polyps: benign and premalignant. In Yamada T, Alpers D, Kaplowitz N, Laine L, Owyang C, Powell D., ed. Textbook of Gastroenterology. 4th ed. Philadelphia: Lippincott Williams and Wilkins.
  • Young, G.P. and Allison, J. (2008). Screening for colorectal cancer. In Yamada T, Alpers D, Kaplowitz N, Laine L, Owyang C, Powell D., ed. Textbook of Gastroenterology. 5th ed. Philadelphia: Lippincott Williams and Wilkins, pp. 170-182.
  • Young, G.P. and Allison, J.E. (2008). Colorectal cancer screening. In Yamada, Tadataka; Alpers, David H; Kalloo, Anthony N; Kaplowitz, Neil; Owyang, Chung; Powell, Don W, ed. Textbook of Gastroenterology. 5 ed. USA: Wiley-Blackwell, pp. 1598-1610.
  • Young, G.P. and Macrae, F.A. (2008). Neoplastic and non-neoplastic polyps of the colon and rectum. In Yamada T, Alpers D, Kaplowitz N, Laine L, Owyang C, Powell D., ed. Textbook of Gastroenterology. 5th ed. Philadelphia: Lippincott Williams and Wilkins, pp. not available-not available.
  • Young, G.P., Rozen, P. and Levin, B. (2006). How does colorectal cancer develop? In Paul Rozen, Graeme Young, Bernard Levin, Stephen Spann, ed. Colorectal Cancer in Clinical Practice: Prevention, Early Detection and Management. 2nd ed. London, UK: Taylor and Francis, pp. 27-46.
  • Young, G.P., Rozen, P. and Levin, B. (2006). How should we screen for early colorectal neoplasia? In Paul Rozen, Graeme Young, Bernard Levin, Stephen Spann, ed. Colorectal Cancer in Clinical Practice: Prevention, Early Detection and Management. 2nd ed. London, UK: Taylor and Francis, pp. 97-129.
  • Young, G.P. and St John, D. (2005). Population screening for colorectal cancer. In Clinical Practice Guidelines for the Prevention, Early Detection and Management of Colorectal Cancer. Canberra, ACT: National Health and Medical Research Council, pp. 32-44.
  • Young, G.P. and Macrae, F.A. (2003). Neoplastic and nonneoplastic polyps of the colon and rectum. In Textbook of Gastroenterology. Philadelphia, USA: Lippincott Williams and Wilkins, pp. 1883-1913.
  • Macrae, F.A., Young, G.P. and Thomas, A.C. (2003). Colorectal polyps: benign and premalignant. In Atlas of Gastroenterology. 3rd ed. Sydney, NSW: Lippincott Williams and Wilkins, pp. 433-454.
  • Young, G.P., Rozen, P. and Levin, B. (2002). How should we screen for early colorectal neoplasia? In Colorectal cancer in clinical practice: Prevention & early detection. London, UK: Taylor and Francis, pp. 77-100.
  • Young, G.P., Rozen, P. and Levin, B. (2002). How does colorectal cancer develop? In Colorectal cancer in clinical practice: Prevention & early detection. London, UK: Taylor and Francis, pp. 23-38.
  • Dr, B., Balachandar, G., Dharmalingam, T., Mortimer, E., Gopalsamy, G., Woodman, R.J., et al. (2014). Effect of native and acetylated high amylose maize starch on fecal pH and short chain fatty acid concentrations in a cohort of children in southern India. In Gastroenterology. The American Society for Gastrointestinal Endoscopy Digestive Disease Week. McCormick Place, Chicago, Illinois. May 2014, pp. 482-482.
    [Web Link]
  • Clarke, J.M., Southwood, J.G., Wundke, R., Toden, S.T., Lockett, T.J., Young, G.P., et al. (2010). Butyrylated starch for treatment of patients with minimal hepatic encephalopathy. In Journal of Gastroenterology and Hepatology . Australian Gastroenterology Week 2010, pp. A113.
  • Ward, P.R., Javanparast, S., Gill, T., Cole, S.R., Tsourtos, G., Young, G.P., et al. (2009). The equity of bowel cancer screening in South Australia: an ecological analysis. In PHAA 39th Annual Conference: making a difference, intervening to improve health outcomes. Canberra: Public Health Association of Australia. PHAA 39th Annual Conference: making a difference, intervening to improve health outcomes. Canberra ACT. Sep 2009.
    [Web Link]
  • Chow, E.C., Lane, J.M., Smith, A., Cole, S.R., Morcom, J.M., Bampton, P.A., et al. (2008). The value of interval fecal occult blood testing in colonoscopy-based surveillance program (CSP) for people at increased risk for colorectal cancer. In Gastroenterology. DDW San Diego 2008, pp. A87-A87.
  • Chow, E.C., Lane, J.M., Cole, S.R., Bampton, P.A. and Young, G.P. (2008). The value of a colonoscopy-based surveillance program (CSP) for people at increased risk for colorectal cancer (CRC) In Gastroenterology. DDW San Diego 2008, pp. A604-A604.
  • Hu, Y., McIntosh, G.H., Le Leu, R.K. and Young, G.P. (2008). Suppression of Colon Cancer by Selenium-Enriched Milk Proteins: Enhanced Apoptotic Response to Carcinogen is Associated with Reduction in Frequency of K-RAS Mutations. In Gastroenterology. DDW San Diego 2008, pp. A634.
  • Le Leu, R.K., Hu, Y., Brown, I.L. and Young, G.P. (2008). Synbiotic combination of bifidobacterium lactis and resistant starch can protect against coloretal cancer development. In Journal of Gastroenterology and Hepatology. Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week. Brisbane, QLD. Oct 2008, pp. A209-A209.
    [10.1111/j.1440-1746.2008.05611.x]
  • Worthley, D.L., Ruszkiewicz, A., Davies, R., Moore, S., Durrant, S., Western, R., et al. (2008). Human Gastric Cancer-Associated Fibroblast-Like Cells are Derived from the Bone Marrow. In Gastroenterology. DDW San Diego 2008, pp. A744.
  • Hu, Y., McIntosh, G.H., Le Leu, R.K. and Young, G.P. (2007). Selenium is protective against colon cancer in azoxymethane-treated mice: influence on molecular targets. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A411-A411.
  • Hu, Y., Le Leu, R.K., McIntosh, G.H. and Young, G.P. (2007). Chemopreventive Effect of High Selenium Enriched Milk Protein on Azoxymethane-Induced Colonic Tumorigenesis. In Gastroenterology. W.B. Saunders. Digestive Disease Week 2007. Washington, DC. May 2007, pp. A-439-A-439.
  • Draper, B.K., Tan, M., Chow, E., Sandford, J.J., Boseley, K., Bampton, P.A., et al. (2007). Delays to discharge can be reduced with improved ward procedures. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A281-A281.
    [10.1111/j.1440-1746.2007.05159.x]
  • Cole, S.R., Smith, A., Upton, J.M. and Young, G.P. (2007). Is single stool sampling as effective as two stool sampling in fecal immunochemical test based screening for colorectal cancer? In Gastroenterology. United States: W. B. Saunders. Digestive Disease Week 2007: Turning Science into Medicine. Washington, DC. May 2007, pp. A314-A314.
  • Bampton, P.A., Sandford, J.J. and Young, G.P. (2007). Implementation of an evidence-based protocol for the management of bleeding peptic ulcer disease. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A335-A335.
    [10.1111/j.1440-1746.2007.05160.x]
  • Le Leu, R.K., Brown, I.L., Hu, Y. and Young, G.P. (2007). Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A412-A412.
    [10.1111/j.1440-1746.2007.05164.x]
  • Young, G.P. (2007). Australia - value of faecal immunochemical tests. In Journal of Gastroenterology and Hepatology. AGW 2007. Kobe, Japan, pp. A127-A127.
    [10.1111/j.1440-1746.2007.05189.x]
  • Worthley, D., Mullighan, C.G., Dean, M.M., Gordon, D.L., Phillips, P., Heatley, S., et al. (2007). Mannose-Binding Lectin Deficiency Does Not Predispose to Helicobacter pylori Infection. In Gastroenterology. W.B. Saunders. Digestive Disease Week 2007. Washington, DC. May 2007, pp. A 709-A 709.
  • Worthley, D., Moore, S., Ruszkiewicz, A.R., Bardy, P., Western, R., Durrant, S., et al. (2007). The contribution of bone marrow derived cells to solid organ malignancy. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A320-A320.
    [10.1111/j.1440-1746.2007.05172.x]
  • Nyskohus, L., Hu, Y., Le Leu, R.K. and Young, G.P. (2007). Relationship between genotoxin-induced DNA damage and homeostatic responses in rat colonic epithelium. In Journal of Gastoenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A316-A316.
    [10.1111/j.1440-1746.2007.05172.x]
  • Nyskohus, L., Hu, Y., Le Leu, R.K. and Young, G.P. (2007). Encapsulated omega-3 fatty acids regulate azoxymethane (AOM)-induced DNA damage in the rat. In Journal of Gastroenterology and Hepatology. Blackwell Publishing. Australian Gastroenterology Week 2007. Perth, WA. Oct 2007, pp. A405-A405.
  • Chow, E., Smith, A., Cole, S.R., Bampton, P.A., Sandford, J.J., Morcom, J., et al. (2006). Value of interval faecal occult blood testing in a colonoscopic based surveillance programme for people at high risk for colorectal cancer [Abstract] In Journal of Gastroenterology and Hepatology. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2006. Adelaide, SA. Oct 2006, pp. A284-A284.
    [10.1111/j.1440-1746.2006.04687.x]
  • Clarke, J.M., Bird, T.R., Topping, D., Young, G.P. and Cobiac, L. (2006). Effect of resistant starch, butyrylated starch and tributyrin on colon cancer in rats [Abstract] In Journal of Gastroenterology and Hepatology: Colon, Rectum and Small Bowel: Australian Gastroenterology Week 2006. Australian Gastroenterology Week 2006. Adelaide, SA. Oct 2006, pp. A270-A270.
    [10.1111/j.1440-1746.2006.04687.x]
  • Michael, M.Z., Wijnhoven, B., Gregory, P.A., James, R.J., Hussey, D.J., Watson, D.I., et al. (2006). Microrna profiling in gastrointestinal tumours. In Proceedings of the Australian Health and Medical Research Congress 2006. 3rd Australian Health and Medical Research Congress 2006. Melbourne, Vic. Nov 2006, pp. 212-212.
  • Cole, S.R., Smith, A.T., Wilson, C., Turnbull, D., Esterman, A.J. and Young, G.P. (2006). An advance notification letter increases participation in a fecal immunochemical test-based colorectal cancer screening program. In Gastroenterology. Suppl2 ed. Philadelphia, Pennsylvania: Wiley Blackwell Saunders. Annual Meeting of the American Gastroenterological Association. Los Angeles, USA. May 2006, pp. A187-A187.
    [10.1016/S0016-5085(06)60008-5]
  • Worthley, D., Bampton, P.A., Cole, S.R., Smith, A.T. and Young, G.P. (2005). Many participants in population screening by FOBT have higher than average risk for colorectal cancer. In Gastroenterology. Suppl2 ed. US: Wiley Blackwell Saunders. Annual Meeting American Gatroenterological Association. Chicago, USA. May 2005, pp. A572-A572.
    [10.1053/j.gastro.2005.04.003]
  • Smith, A., Cole, S.R. and Young, G.P. (2005). How many colonoscopies are needed to detect advanced neoplasia in population screening using fecal immunochemical occult blood tests? [Abstract] In Journal of Gastroenterology and Hepatology: Colon, Rectum and Small Bowel. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2005. Brisbane, Qld, pp. A28-A28.
    [10.1111/j.1440-1746.2005.04091_2.x]
  • Duszynski, A., Flight, I., Wilson, C., Turnbull, D., Cole, S.R. and Young, G.P. (2005). Intersecting electronic decision support with user modelling in a web-based consumer decision aid for colorectal cancer screening. In User Modelling 2005: 10th International Conference on User Modelling, 24-29 July, 2005:www1-www4. User Modelling 2005: 10th International Conference on User Modelling, Edinburgh, Scotland, UK. Jul 2005.
  • Worthley, D.L., Bampton, P.A., Cole, S.R., Smith, A. and Young, G.P. (2005). Many participants in FOBT screening have a higher than average risk for colorectal cancer [Abstract] In Journal of Gastroenterology and Hepatology: Colon, Rectum and Small Bowel. Massachusettts: Blackwell Publishing. Australian Gastroenterology Week 2005. Brisbane, Qld, pp. A30-A30.
    [10.1111/j.1440-1746.2005.04091_2.x]
  • Cole, S.R., Young, G.P., Roosa, N., Mehaffey, S.J., Smith, A., Esterman, A.J., et al. (2004). Behavioural differences between participants and nonparticipants in colorectal cancer screening. In Journal of Gastroenterology and Hepatology. Carlton, VIC: Blackwell Publishing. Australian Gastroenterology Week, pp. A198-A198.
    [10.1111/j.1440-1746.2004.3615_2.x]
  • Cole, S.R., Turnbull, D., Smith, A., Mehaffey, S.J., Severino, J. and Young, G.P. (2004). Psychosocial and demographic differences between participants and non-participants in bowel cancer screening. In International Journal of Behavioral Medicine. Mahwah, NJ: Lawrence Erlbaum Associates Inc.. Eighth international congress of behavioural medicine: integrating social and behavioural sciences with medicine and public health. Mainz, Germany, pp. 302-302.
  • Cole, S.R., Cadd, B., Smith, A., Morcom, J. and Young, G.P. (2004). Colorectal cancer screening behaviour is influenced by screening test technology. In International Journal of Behavioral Medicine. New Jersey, USA: Lawrence Erlbaum Associates Inc.. Eighth international congress of behavioural medicine: integrating social and behavioural sciences with medicine and public health. Mainz, Germany, pp. 69-69.
  • Bampton, P., Sandford, J.J., Cole, S.R., Smith, A., Morcom, J., Cadd, B., et al. (2004). Interval fecal occult blood testing in a colonoscopy-based colorectal cancer surveillance program detects additional pathology. In Gastroenterology. Philadelphia, USA: W B Saunders Co.
  • Smith, A., Cole, S.R., Young, G.P., Morcom, J., Lapointe, L.C. and Chandler, H.M. (2004). A quantifiable faecal immunochemical test (FIT) for haemoglobin facilitates balancing sensitivity with specificity when screening for colorectal cancer. In Journal of Gastroenterology and Hepatology. Carlton, VIC: Blackwell Publishing. Australian Gastroenterology Week, pp. A195-A195.
    [10.1111/j.1440-1746.2004.3615_2.x]
  • Young, G.P., Cole, S.R., Roosa, N., Mehaffey, S.J., Smith, A.T., Esterman, A.J., et al. (2004). Behavioural differences between participants and non-participants in colorectal cancer (CRC) screening. In Gastroenterology. Suppl2 ed. US: Wiley Blackwell Saunders. Annual Meeting American Gastroenterology Association. New Orleans, USA. May 2004, pp. A194-A194.
    [10.1016/S0016-5085(04)80009-X]
  • Worthley, D.L., Cole, S.R., Mehaffey, S.J., Smith, A., Turnbull, D. and Young, G.P. (2004). The participants' perception of faecal occult blood test screening for colorectal cancer: a questionnaire based study. In Journal of Gastroenterology and Hepatology. Carlton, VIC: Blackwell Publishing. Australian Gastroenterology Week, pp. A219-A219.
    [10.1111/j.1440-1746.2004.3615_2.x]
  • Worthley, D.L., Cole, S.R., Mehaffey, S.J., Smith, A., Turnbull, D. and Young, G.P. (2004). A questionnaire based assessent of barriers to participation in faecal occult blood test screening for colorectal cancer: why they choose to refuse. In Journal of Gastroenterology and Hepatology. Carlton, Victoria: Blackwell Publishing. Australian Gastroenterology Week, pp. A196-A196.
    [10.1111/j.1440-1746.2004.3615_2.x]
  • Worthley, D., Cole, S.R., Mehaffey, S.J., Smith, A., Turnbull, D. and Young, G.P. (2004). A questionnaire based assessment of barriers to participation in faecal occult blood test screening for colorectal cancer: why they choose to refuse [Abstract] In Journal of Gastroenterology and Hepatology: Colon Rectum and Small Bowel. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2004. Cairns, Qld. Oct 2004, pp. A196-A196.
    [10.1111/j.1440-1746.2004.3615_2.x]
  • Smith, A.T., Young, G.P., Cole, S.R., Morcom, J.M., Chandler, H.M. and Lapointe, L.C. (2004). A quantifiable faecal immunochemical test (FIT) for haemoglobin facilitates balancing sensitivity with specifity when screening for colorectal cancer (Abstract). In Gastroenterology. Philadelphia, Pennsylvania: W. B. Saunders. Annual Meeting American Gastroenterological Association. New Orleans, USA. May 2004, pp. A199-A199.
  • Brown, G., James, R.J. and Young, G.P. (2003). Modified bovine pancreatic ribonuclease a is a weak intracellular cytotoxin. (Abstract) In Ishii, Tandon, RK, ed. Journal of Gastroenterology & Hepatology. Carlton, NSW, Australia: Blackwell Publishing. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B35.
  • Cole, S.R., Smith, A., Bampton, P., Sandford, J.J., Morcom, J. and Young, G.P. (2003). Screening for colorectal cancer: direct comparison of a brush-sampling fecal immunochemical test for hemoglobin with hemoccult [Abstract] In Brenner, DA, ed. Gastroenterology. Philadelphia, USA: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A80-A80.
  • Hu, Y. and Young, G.P. (2003). Does p53 haploinsufficiency predispose to azoxymethane (AOM)-induced colon cancer? (Abstract) In Brenner, DA, ed. Gastroenterology. Philadelphia, USA: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A131.
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2003). Effect of sulindac on acute apoptotic response to carcinogen in p53 knockout mice. (Abstract) In Ishii, H Tandon, RK, ed. Journal of Gastroenterology & Hepatology. Carlton, NSW, Australia: Blackwell Publishing. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B27.
  • Lapointe, L.C., Young, G.P. and Chandler, H.M. (2003). Analysis of mRNA expression profiles in colorectal adenomas using K-nearest neighbor cluster analysis [Abstract] In Brenner, DA, ed. Gastroenterology. Philadelphia, USA: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A650-A650.
  • Smith, A., Cole, S.R., Morcom, J., Sandford, J.J., Bampton, P. and Young, G.P. (2003). Colorectal cancer screening: direct comparison of a brush-sampling faecal immunochemical test for haemoglobin with a guaiac FOBT [Abstract] In Ishii, H Tandon, RK, ed. Journal of Gastroenterology and Hepatology. Carlton: Blackwell Science Ltd. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B24-B24.
    [10.1046/j.1440-1746.18.s2.3.x]
  • Martin, J.E., Le Leu, R.K. and Young, G.P. (2003). Flurizan and sulindac inhibition of colorectal cancer is dependent on histologic type (Abstract) In Ishii, H Tandon, RK, ed. Journal of gastroenterology and hepatology. U.K: Blackwell Scientific Publications. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B28.
  • Martin, J.E., Le Leu, R.K., Hu, Y. and Young, G.P. (2003). Prevention of colorectal carcinoma in azoxymethane treated rats by non-steroidal anti-inflammatory drugs (NSAIDS) is dependent on histologic type (Abstract) In Brenner, DA, ed. Gastroenterology. Philadelphia: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A604-A604.
  • Ramnath, G.J., Olesnicki, A., Cole, S.R., Esterman, A.J., Bampton, P. and Young, G.P. (2003). Yield of significant neoplasia in three clinically indicated settings for colonoscopy [Abstract] In Brenner, DA, ed. Gastroenterology. Philadelphia: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A647-A648.
  • Sandford, J.J., Bampton, P. and Young, G.P. (2003). Sustaining a process for implementing best practice and maintaining participation in colorectal cancer surveillance. (Abstract) In Ishii, H Tandon, RK, ed. Journal of Gastroenterology & Hepatology. Carlton: Blackwell Science Ltd. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B14.
    [10.1046/j.1440-1746.18.s2.1.x]
  • Smith, A., Cadd, B., Morcom, J., Byrne, D.T., Guy, J.R., Cole, S.R., et al. (2003). Relationship between ongoing participation in colorectal cancer screening and method of invitation [Abstract] In David A Brenner, ed. Gastroenterology. Philadelphia, USA: W B Saunders Co. Digestive Disease Week & the 104th Annual Meeting of the American Gastroenterological Association. Orlando, USA. Aug 2003, pp. A56-A56.
  • Le Leu, R.K., Brown, I.L., Hu, Y. and Young, G.P. (2003). Probiotic bacteria, when combined with the prebiotic resistant starch, can facilitate apoptosis of DNA-damaged cells. (Abstract) In Ishii, HTandon, RK, ed. Journal of Gastroenterology & Hepatology. Carlton, NSW, Australia: Blackwell Publishing. Australian Gastroenterology Week 2003. Cairns, QLD. Oct 2003, pp. B102.
  • Bampton, P.A., Sandford, J.J., Cadd, B., Cole, S.R. and Young, G.P. (2002). Interval annual faecal occult blood testing detects further lesions in a colonoscopy-based screening surveillance program (Abtract) In Gastroenterology. Philadelphia, Pennsylvania: W. B. Saunders. Annual Meeting American Gastroenterological Association. Sanfrancisco, USA. May 2002, pp. A589-A590.
  • Young, G.P., St John, D.J.B., Cole, S.R., Sinatra, M.A., Bielecki, B.E., Bennett, J., et al. (2002). Sensitivity and specificity for adenomas and cancers of a new quantifiable occult blood test (!nSure®) In Journal of Gastroenteroloy and Hepatology. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2002. Adelaide, SA, pp. A122-A122.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Young, G.P., Cole, S.R., Cadd, B. and Morcom, J. (2002). Population participation in screening improves markedly using an immunochemical fecal occult blood test with simplified fecal sampling (Abstract) In Gastroenterology. Philadelphia, Pennsylvania: W. B. Saunders. Annual Meeting American Gastroenterological Association. Sanfrancisco, USA. May 2002, pp. A484-A484.
  • Young, G.P., Cole, S.R., Cadd, B. and Morcom, J. (2002). Participation in colon cancer screening improves using a faecal occult blood test with improved technology [Abstract] In Journal of Gastroenterology and Hepatology. Massachusetts: Blackwell Publishing. Australian Gastroenterology Week 2002. Adelaide, SA. Oct 2002, pp. A120-A120.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Wigg, A.J., Phillips, J.W., Young, G.P. and Berry, M.N. (2002). Mild hypothermia inhibits oxidative stress, apoptosis and necrosis in hepatocyte suspension culture. In Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week 2002. Adelaide, Australia. Oct 2002.
  • Cole, S.R., Roosa, N., Mehaffey, S.J., Young, G.P. and Turnbull, D. (2002). Attitudes towards colorectal cancer screening [Abstract] In Journal of Gastroenterology and Hepatology. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2002. Adelaide, SA. Oct 2002, pp. A119-A119.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Cole, S.R., Sandford, J.J., Cadd, B., Young, G.P. and Bampton, P.A. (2002). Yield of a colonoscopic based surveillance program is enhanced by interval faecal occult blood testing [Abstract] In Journal of Gastroenterology and Hepatology. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2002. Adelaide, SA, pp. A96-A96.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Cole, S.R., Smith, A., Cadd, B., Morcom, J., Byrne, D., Guy, J.R., et al. (2002). Screening for colorectal cancer: population participation and yield over time [Abstract] In Journal of Gastroenterology and Hepatology. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterology Week 2002. Adelaide, SA. Oct 2002, pp. A122-A122.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Ramnath, G.J., Bampton, P.A., Sandford, J.J., Cole, S.R. and Young, G.P. (2002). Screening colonoscopy vs faecal occult blood testing: what is the yield? In Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week. Adelaide, SA. Oct 2002, pp. A101-A101.
    [10.1046/j.1440-1746.17.s5.3.x]
  • Cole, S.R., Cadd, B., Sandford, J.J., Young, G.P. and Bampton, P.A. (2001). Interval faecal occult blood testing in a colonoscopy based screening program (Abstract). In Journal of Gastroenterology and Hepatology. S1 ed. Massachusetts, USA: Blackwell Publishing. Australian Gastroenterolgy Week 2001, pp. A17-A17.
  • Cole, S.R., Sandford, J.J., Cadd, B., Bennett, J., Young, G.P. and Bampton, P.A. (2001). Interval fecal occult blood testing in a colonoscopy based screening program (Abstract). In Gastroenterology. S1 ed. Philadelphia, Pennsylvania: W. B. Saunders. Annual Meeting American Gastroenterological Association. Atlanta, USA. May 2001, pp. A603-A603.
  • Young, G.P., St John, D.J.B., Sinatra, M.A., Cole, S.R., Bielecki, B.E., Bennett, J., et al. (2001). Evaluation of a quantifiable immunochemical fecal occult test with simplified fecal sampling (Abstract). In Gastroenterology. S1 ed. Philadelphia, Pennsylvania: W. B. Saunders. Annual Meeting American Gastroenterological Assocation. Atlanta, USA. May 2001, pp. A599-A599.
  • Wigg, A.J., Bampton, P.A. and Young, G.P. (2000). The effect of blood on the sensitivity of the rapid urease test. In Gastroenterology. Digestive Disease Week and the 101st Annual Meeting of the American Gastroenterological Association. May 2000, pp. A1323.
  • Wigg, A.J., Bampton, P.A. and Young, G.P. (2000). The effect of blood on the sensitivity of the rapid urease test. In Journal of Gastroenterology and Hepatology. Australian Gastroenterology Week scientific conference, pp. J94.
  • Fraser, C.G., Allison, J.E., Young, G.P. and Halloran, S.P. (2013). Quantitation of Hemoglobin Improves Fecal Immunochemical Tests for Noninvasive Screening. Clinical Gastroenterology and Hepatology, 11(7) pp. 839-840.
    [http://dx.doi.org/10.1016/j.cgh.2013.02.031] [Scopus]
  • Fraser, C.G., Halloran, S.P., Allison, J.E. and Young, G.P. (2013). Making colorectal cancer screening FITTER for purpose with quantitative faecal immunochemical tests for haemoglobin (FIT) Clinical Chemistry and Laboratory Medicine, 51(11) pp. 2065-2067.
  • Young, G. and Group, W. (2013). European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication. Endoscopy, 1 pp. 51-59.
    [10.1055/s-0032-1325997]
  • Allison, J., Fraser, C., Halloran, S. and Young, G. (2012). Comparing fecal immunochemical tests: improved standardization is needed. Gastroenterology, 142(3) pp. 422-424.
    [10.1053/j.gastro.2012.01.015]
  • Fraser, C.G., Allison, J.E., Young, G.P. and Halloran, S.P. (2012). Newer Fecal Tests: opportunities for Professionals in Laboratory Medicine. Clinical Chemistry, 58(6) pp. 963-965.
  • Head, R.J., Young, G.P. and LaPointe, L.C. (2012). Colorectal cancer: towards control by prevention. Medical Journal of Australia, 197(3) pp. 136-136.
    [10.5694/mja12.10830]
  • Olver, I.N. and Young, G.P. (2012). The urgency of saving lives through bowel cancer screening. MJA Medical Journal of Australia, 196(8) pp. 490-491.
  • Young, G., Fraser, C., Halloran, S. and Cole, S. (2012). Guaiac based faecal occult blood testing for colorectal cancer screening: an obsolete strategy. Gut, 61(7) pp. 959-960.
    [10.1136/gutjnl-2011-301810]
  • Young, G.P. and Bosch, L.J.W. (2011). Fecal Tests: From Blood to Molecular Markers. Current Colorectal Cancer Reports, 7 pp. 62-70.
    [10.1007/s11888-010-0084-8]
  • Bird, A.R., Topping, D.L. and Young, G.P. (2009). Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome [correspondence] New England Journal of Medicine, 14 pp. 1462.
    [Scopus]
  • Young, G.P. (2009). Population-based screening for colorectal cancer: Australian research and implementation. Journal of Gastroenterology and Hepatology, 24(Suppl 3)
    [10.1111/j.1440-1746.2009.06069.x] [Scopus]
  • Young, G. and Cole, S. (2009). Which fecal occult blood test is best to screen for colorectal cancer? Nature Reviews. Gastroenterology and Hepatology, 6(3) pp. 140-141.
    [10.1038/ncpgasthep1358]
  • Winawer, S.J., Classen, M., Lambert, R., Fried, M., Dite, P., Goh, K.L., et al. (2008). Colorectal cancer screening: practice guideline (short version) World Gastroenterology News, 12(2) pp. 17-22.
    [Web Link]
  • Young, G.P. (2008). What do we know about diet and cancer? A look at the report from the World Cancer Research Fund. Nutridate, 19 pp. 1-4.
  • Young, G.P. (2007). Comparison of a brush-sampling fecal immunochemical test for hemoglobin with a sensitive guaiac-based fecal occult blood test in detection of colorectal neoplasia - Author reply. Cancer, 109(9) pp. 1926-1926.
    [10.1002/cncr.22612] [10.1002/cncr.22612] [Scopus]
  • Young, G.P. (2007). Post-polypectomy surveillance: who and how? Practical Gastroenterology, 31(7) pp. 19-25.
    [Scopus] [Web Link]
  • Worthley, D., Cole, S.R. and Young, G.P. (2005). Fecal DNA for colorectal-cancer screening. New England Journal of Medicine, 352(13) pp. 1384-1385.
    [10.1056/NEJM200503313521323] [Scopus]
  • Bampton, P.A., Looker, J., Smith, A., Cole, S.R. and Young, G.P. (2005). Negative interval fit in a colonoscopic based screening program identifies subjects at lower risk of recurrent pathology. Journal of Gastroenterology and Hepatology, 20(S1) pp. A9-A9.
    [10.1111/j.1440-1746.2005.04091_1.x]
  • Young, G.P. and Worthley, D. (2005). Screening with a fecal multitarget dna test. Gastroenterology, 129(2) pp. 757-759.
    [10.1016/j.gastro.2005.04.039] [10.1053/j.gastro.2005.04.039] [Scopus]
  • Ward, P., Javanparast, S., Ah Matt, M., Cole, S., Aylward, P., Gill, T., et al. (2010). Equity of bowel cancer screening: An epidemiological and qualitative Study. Final Report.
  • Rozen, P., Young, G.P., Levin, B. and Spann, S.J. (2006). Editors. Colorectal cancer in clinical practice: Prevention, early detection and management. 2nd ed. London: Taylor and Francis, pp. 1-175.
  • Young, G.P. and Rozen, P. (2006). Fecal immunochemical tests (FITs) for hemoglobin: a paradigm shift in noninvasive fecal screening tests for colorectal cancer. World Gastroenterology News. 11(1) pp. 22-24.
    [Web Link]
  • Young, G.P. and Worthley, D. (2005). The Aspirin, Bran and Calcium of Colorectal cancer chemoprevention. May 2005
    [Web Link]
  • Sandford, P.J., Young, G.P. and Bampton, P. (2001). National Demonstration Hospitals Program Phase 3. Health Service Research Reports, pp. 23-24.
  • Brown, I.L., Birkett, A.M., Le Leu, R.K. and Young, G.P. (2008). Probiotic/Non-Probiotic Combinations. Patent: 11/773729 United States. Patent owner: National Starch and Chemical Investment Holding Corporation
  • Lapointe, L.C., Young, G.P., Molloy, P.L., Dunne, R., Lockett, T. and Wilson, W.J. (2007). OFF Genes "a method of diagnosing neoplasms - II" Patent: 60/982,115 United States. Patent owner: LaPointe L, Young G, Molloy R, Dunne A, Lockett T, Wilson W
  • Lapointe, L.C., Young, G.P., Dunne, R., Lockett, T. and Wilson, W.J. (2007). ON Genes "a method of diagnosing neoplasms" Patent: 60/982,114 United States. Patent owner: LaPointe L, Young G, Dunne R, Lockett T, Wilson W
  • McIntosh, G.H., Hu, Y. and Young, G.P. (2014). Food selenium and the prevention of colorectal cancer. In 3rd International Conference on Selenium in the Environment and Human Health. 3rd International Conference on Selenium in the Environment and Human Health. Hefei, China. Nov 2014, pp. 48-49.
  • Le Leu, R.K., Worthley, D.L., Hu, Y., Brown, L.L. and Young, G.P. (2009). A combination of Bifidobacterium lactis and resistant starch can protect against colorectal cancer development. In Proceedings of the 59th Australian Cereals Chemistry Conference. 59th Australian Cereals Chemistry Conference. North Ryde.
  • Brown, I.L., Henriksson, A., Le Leu, R.K. and Young, G.P. (2007). Resistant Starch and targeted Synbiotics. In Cereals 2006. Melbourne, Australia: Royal Australian Chemical Institute,. Cereals 2006, pp. 388-391.
  • Flight, I., Wilson, C., Duszynski, A., Turnbull, D., Cole, S.R. and Young, G.P. (2005). Electronic tailoring of information on the basis of perceived risk and health-beliefs: a method for increasing uptake of colorectal cancer screening? In Sara Rubinelli and Joachim Haes, ed. Tailoring health messages: bridging the gap between social and humanistic perspectives on health communication. Lugano: Health Care Communication Laboratory University of Lugano. University of Lugano International Conference 2005. Monte Verità. Jul 2005, pp. 31-35.
    [Web Link]
  • kumar, R., Price, T., Beeke, C., Jain, K., Patel, G., Padbury, R., et al. (2014). Colorectal Cancer Survival: An Analysis of Patients With Metastatic Disease Synchronous and Metachronous With the Primary Tumor. Clinical Colorectal Cancer,
    [10.1016/j.clcc.2013.11.008]
  • Young, J., Win, A.K., Rosty, C., Flight, I.H., Roder, D., Young, G., et al. (2014). Rising incidence of early-onset colorectal cancer in Australia over two decades: Report and review. Journal of Gastroenterology and Hepatology, epub(Sep 22nd)
  • Winter, J., Young, G., Hu, Y., Gratz, S., Conlon, M. and Le Leu, R. (2014). Accumulation of promutagenic DNA adducts in the mouse distal colon after consumption of heme does not induce colonic neoplasms in the western diet model of spontaneous colorectal cancer. Molecular Nutrition and Food Research, 58(3) pp. 550-558.
    [PubMed]
  • Pedersen, S., Mitchell, S., Graham, L., McEvoy, A., Thomas, M., Baker, R., et al. (2014). CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. Epigenetics, 9(5)
  • Mitchell, S., Ross, J., Drew, H., Ho, T., Brown, G., Saunders, N., et al. (2014). A panel of genes methylated with high frequency in colorectal cancer. BMC Cancer, 14(54)
  • Humphreys, K.J., Conlon, M., Young, G., Topping, D., Hu, Y., Winter, J., et al. (2014). Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomised trial. Cancer Prevention Research, 7(8) pp. 786-795.
  • Binder, H.J., Brown, I., Ramakrishna, B.S. and Young, G.P. (2014). Oral Rehydration Therapy in the Second Decade of 21st Century. Current Gastroenterology Reports (Online) 16(3) pp. 376-376.
  • Fraser, C.G., Allison, J.E., Young, G.P., Halloran, S.P. and Seaman, H. (2014). A standard for Faecal Immunochemical TesTs for haemoglobin evaluation reporting (FITTER). Annals of Clinical Biochemistry, 51(2) pp. 301-302.
  • Win, A.K., Parry, S., Parry, B., Kalady, M.F., Macrae, F.A., Ahnen, D.J., et al. (2013). Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers. Annals of Surgical Oncology, 20(6) pp. 1829-1836.
    [10.1245/s10434-012-2858-5]
  • Win, A.K., Hopper, J., Buchanan, D., Young, J., Tenesa, A., Dowty, J., et al. (2013). Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers? European Journal of Cancer, 49(7) pp. 1578-1587.
    [10.1016/j.ejca.2013.01.029]
  • kumar, R., Jain, K., Beeke, C.F., Price, T., Townsend, A., Padbury, R., et al. (2013). A population-based study of metastatic colorectal cancer in individuals aged >= 80 years: Findings from the South Australian Clinical Registry for Metastatic Colorectal Cancer. Cancer, 119(4) pp. 722-728.
    [10.1002/cncr.27802]
  • Zajac, I., Flight, I., Turnbull, D., Young, G., Cole, S. and Wilson, C. (2013). Self-reported bowel screening rates in older Australians and its implications for public health screening programmes. Australasian Medical Journal, 6(8) pp. 411-417.
    [10.4066/AMJ.2013.1808]
  • Bobridge, A., Cole, S., Schoeman, M., Lewis, H., Bampton, P. and Young, G. (2013). The National Bowel Cancer Screening Program: Consequences for practice. Australian Family Physician, 42(3) pp. 141-145.
    [Scopus] [Web Link]
  • Cole, S.R., Tucker, G.R., Osborne, J.M., Byrne, S.E., Bampton, P.A., Fraser, R.J.L., et al. (2013). Shift to earlier stage at diagnosis as a consequence of the National Bowel Cancer Screening Program. Medical Journal of Australia, 198(6) pp. 327-330.
    [10.5694/mja12.11357]
  • Dowty, J., Win, A.K., Buchanan, D., Lindor, N., Macrae, F., Clendenning, M., et al. (2013). Cancer risks for MLH1 and MSH2 mutation carriers. Human Mutation, 34(3) pp. 490-497.
    [10.1002/humu.22262]
  • Gregory, T., Cole, S., Wilson, C., Flight, I., Zajac, I., Turnbull, D., et al. (2013). Exploring the validity of the Continuum of Resistance model for discriminating early from late and no-uptake of colorectal cancer screening: Implications for the design of invitation and reminder letters. International Journal of Behavioral Medicine, 20(4) pp. 572-581.
    [10.1007/s12529-012-9254-1] [Scopus]
  • Hu, Y., McIntosh, G.H., Le Leu, R., Nyskohus, L., Woodman, R. and Young, G.P. (2013). Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers. PLoS One, 8(5) pp. e64362.
    [10.1371/journal.pone.0064362]
  • Le Leu, R., Young, G., Hu, Y., Winter, J. and Conlon, M. (2013). Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation. Digestive Diseases and Sciences, 58(12) pp. 3475-3482.
    [10.1007/s10620-013-2844-1]
  • Martin, J.E., Young, G., Le Leu, R. and Hu, Y. (2013). Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model. Anticancer Research, 33(9) pp. 3581-3588.
    [Scopus] [Web Link]
  • Nyskohus, L., Watson, A., Margison, G., Le Leu, R., Kim, S.W., Lockett, T., et al. (2013). Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis. Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 758(1-2) pp. 80-86.
    [10.1016/j.mrgentox.2013.10.001] [Scopus]
  • Oster, C., Zajac, I., Flight, I., Hart, E., Young, G., Wilson, C., et al. (2013). Ambivalence and its influence on participation in screening for colorectal cancer. Qualitative Health Research, 23(9) pp. 1188-1201.
    [10.1177/1049732313501890]
  • Rand, K., Young, G., Ho, T. and Molloy, P. (2013). Sensitive and selective amplification of methylated DNA sequences using helper-dependent chain reaction in combination with a methylation-dependent restriction enzymes. Nucleic Acids Research, 41(1) pp. e15.
    [10.1093/nar/gks831]
  • Ross, J., Lockett, L., Brookes, D., Tabor, B., Duesing, K., Buckley, M., et al. (2013). An association between the PTGS2 rs5275 polymorphism and colorectal cancer risk in families with inherited non-syndromic predisposition. European Journal of Human Genetics, 21 pp. 1389-1395.
    [10.1038/ejhg.2013.53]
  • Young, G.P. (2012). New Developments in Screening for Colorectal Cancer: Report on the World Endoscopy Organisation Workshop. Practical Gastroenterology, 9 pp. 28-36.
  • Cicek, M., Cunningham, J., Fridley, B., Serie, D., Bamlet, W., Diergaarde, B., et al. (2012). Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22. PLoS One, 7(5) pp. e38175.
    [10.1371/journal.pone.0038175]
  • Zajac, I., Flight, I., Wilson, C., Turnbull, D., Cole, S. and Young, G. (2012). Internet usage and openness to internet-delivered health information among Australian adults aged over 50 years. Australasian Medical Journal, 5(5) pp. 262-267.
    [10.4066/AMJ.2012.1065] [Scopus]
  • Clarke, J., Young, G., Topping, D., Bird, A., Cobiac, L., Scherer, B., et al. (2012). Butyrate delivered by butyrylated starch increases distal colonic epithelial apoptosis in carcinogen-treated rats. Carcinogenesis, 33(1) pp. 197-202.
    [10.1093/carcin/bgr254] [Scopus]
  • Cole, S.R., Gregory, T.A., Whibley, A., Ward, P., Turnbull, D., Wilson, C., et al. (2012). Predictors of Re-Participation in Faecal Occult Blood Test-Based Screening for Colorectal Cancer. Asian Pacific Journal of Cancer Prevention, 13(12) pp. 5989-5994.
    [10.7314/APJCP.2012.13.12.5989]
  • Collins, M., Teo, E., Cole, S., Chan, C., McDonald, S., Russ, G., et al. (2012). Screening for colorectal cancer and advanced colorectal neoplasia in kidney transplant recipients: cross sectional prevalence and diagnostic accuracy study of faecal immunochemical testing for haemoglobin and colonoscopy. BMJ Open, 345(e4657)
    [10.1136/bmj.e4657]
  • Duncan, A., Turnbull, D., Gregory, T., Cole, S., Young, G., Flight, I., et al. (2012). Using the Transtheoretical Model of Behaviour Change to describe readiness to rescreen for colorectal cancer with faecal occult blood testing. Health Promotion Journal of Australia, 23(2) pp. 122-128.
    [10.1071/HE12122] [Scopus]
  • Fraser, C., Allison, J., Halloran, S. and Young, G. (2012). A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin. Journal of The National Cancer Institute, 104(11) pp. 810-814.
    [10.1093/jnci/djs190]
  • LaPointe, L.C., Pedersen, S., Dunne, R., Brown, G., Pimlott, L., Guar, S., et al. (2012). Discovery and validation of molecular biomarkers for colorectal adenomas and cancer with application to blood testing. PLoS One, 7(1) pp. e29059.
    [10.1371/journal.pone.0029059]
  • Osborne, J., Wilson, C., Moore, V., Gregory, T., Flight, I. and Young, G. (2012). Sample preference for colorectal cancer screening tests: Blood or Stool? Open Journal of Preventive Medicine, 2(3) pp. 326-331.
    [10.4236/ojpm.2012.23047]
  • Saunders, I., Ross, J., Macrae, F., Young, G., Blanco, I., Brohede, J., et al. (2012). Evidence of linkage to chromosomes 10p15.3-p15.1, 14q24.3-q31.1 and 9q33.3-q34.3 in non-syndromic colorectal cancer families. European Journal of Human Genetics, 20(1) pp. 91-96.
    [10.1038/ejhg.2011.149] [Scopus]
  • Win, A.K., Lindor, N., Young, J., Macrae, F., Young, G., Williamson, E., et al. (2012). Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome. Journal of The National Cancer Institute, 104(18) pp. 1363-1372.
    [10.1093/jnci/djs351]
  • Winter, J.M., Nyskohus, L., Young, G.P., Hu, Y., Conlon, M., Bird, A.R., et al. (2012). Inhibition by Resistant Starch of Red Meat-Induced Promutagenic Adducts in Mouse Colon. Cancer Prevention Research, pp. 1920-1928.
    [10.1158/1940-6207.CAPR-11-0176] [Scopus]
  • Win, A.K., Young, J.P., Lindor, N., Tucker, K., Ahnen, D.J., Young, G., et al. (2012). Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. Journal of Clinical Oncology, 30(9) pp. 958-964.
    [10.1200/JCO.2011.39.5590]
  • Worthley, D., Whitehall, V.L., Le Leu, R.K., Irahara, N., Buttenshaw, R.L., Mallitt, K., et al. (2011). DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids. Digestive Diseases and Sciences, 56((2)) pp. 387-396.
    [10.1007/s10620-010-1312-4] [Scopus]
  • Win, A.K., Dowty, J., English, D., Campbell, P., Young, J.P., Winship, I., et al. (2011). Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes. British Journal of Cancer, 105 pp. 162-169.
    [10.1038/bjc.2011.172] [Scopus]
  • Ward, P.R., Javanparast, S., Ah Matt, M.L., Martini, A., Tsourtos, G., Cole, S.R., et al. (2011). Equity of colorectal cancer screening: cross-sectional analysis of National Bowel Cancer Screening Program data for South Australia. Australian and New Zealand Journal of Public Health, 35(1) pp. 61-65.
    [10.1111/j.1753-6405.2010.00637.x] [Scopus]
  • Parry, S., Win, A.K., Parry, B., Macrae, F.A., Gurrin, L.C., Church, J.M., et al. (2011). Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery. Gut, 60(7) pp. 950-957.
    [10.1136/gut.2010.228056] [Scopus]
  • Graham, L., Pedersen, S., Brown, G., Ho, T., Kassir, Z., Moynihan, A., et al. (2011). Colorectal Neoplasia Differentially Expressed (CRNDE), a Novel Gene with Elevated Expression in Colorectal Adenomas and Adenocarcinomas. Genes & Cancer, 2(8) pp. 829-840.
    [10.1177/1947601911431081] [Scopus]
  • Martini, A., Javanparast, S., Ward, P., Baratiny, G., Gill, T., Cole, S., et al. (2011). Colorectal cancer screening in rural and remote area: analysis of the National Bowel Cancer Screening Program data for South Australia. Rural and Remote Health, 11(2) pp. 1648.
    [Scopus]
  • Hu, Y., McIntosh, G.H., Le Leu, R.K., Upton, J.M., Woodman, R.J. and Young, G.P. (2011). The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects. British Journal of Nutrition, 106(4) pp. 572-582.
    [10.1017/S0007114511000420] [Scopus]
  • Hollington, P., Tiong, L. and Young, G.P. (2011). Timing and detection of metachronous colorectal cancer. ANZ Journal of Surgery, 81 pp. 272-274.
    [10.1111/j.1445-2197.2010.05574.x] [Scopus]
  • Gregory, T., Wilson, C., Duncan, A., Turnbull, D., Cole, S. and Young, G.P. (2011). Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer. BMC Public Health, 11(38)
    [10.1186/1471-2458-11-38] [Scopus]
  • Martini, A., Javanparast, S., Ward, P., Cole, S.R., Aylward, P., Baratiny, G., et al. (2011). Screening for colorectal cancer in remote, rural and metropolitan South Australia: analysis of the National Bowel Cancer Screening Program data. Public Health Bulletin South Australia, 8(1) pp. 49-55.
  • Buchanan, D.D., Sweet, K., Drini, M., Jenkins, M., Win, A.K., Gattas, M., et al. (2010). Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study. International Journal of Colorectal Disease, 25 pp. 703-712.
    [10.1007/s00384-010-0907-8] [10.1007/s00384-010-0907-8] [Scopus]
  • Cole, S.R., Zajac, I., Gregory, T.A., Mehaffey, S.J., Roosa, N., Turnbull, D., et al. (2010). Psychosocial variables associated with colorectal cancer screening in South Australia. International Journal of Behavioral Medicine, pp. 302-309.
    [10.1007/s12529-010-9101-1] [10.1007/s12529-010-9101-1] [Scopus]
  • He, X., Hu, Y., Winter, J. and Young, G.P. (2010). Anti-mutagenic lichen extract has double-edged effect on azoxymethane-induced colorectal oncogenesis in C57BL/6J mice. Toxicology Mechanisms and Methods, 20(1) pp. 31-35.
    [10.3109/15376510903521232] [10.3109/15376510903521232] [Scopus]
  • Hu, Y., McIntosh, G.H., Le Leu, R.K. and Young, G.P. (2010). Selenium-enriched milk proteins and selenium yeast affect selenoproteins activity and expression differently in mouse colon. British Journal of Nutrition, 104 pp. 17-23.
    [10.1017/S0007114510000309] [10.1017/S0007114510000309] [Scopus]
  • Javanparast, S., Ward, P.R., Cole, S.R., Gill, T., Ah Matt, M.L., Aylward, P., et al. (2010). A cross-sectional analysis of participation in National Bowel Cancer Screening Program in Adelaide by age, gender and geographical location of residence. Australasian Medical Journal, 1(1) pp. 141-146.
    [10.4066/AMJ.2010.198] [10.4066/AMJ.2010.198] [Scopus]
  • Javanparast, S., Ward, P.R., Young, G.P., Wilson, C., Carter, S., Misan, G., et al. (2010). How equitable are colorectal cancer screening programs which include FOBTs? A review of qualitative and quantitative studies. Preventive Medicine, 50 pp. 165-172.
    [10.1016/j.ypmed.2010.02.003] [Scopus] [PubMed]
  • Lane, J.M., Chow, E., Young, G.P., Good, N., Smith, A.T., Bull, J.A., et al. (2010). Interval Fecal Immunochemical Testing in a Colonoscopic Surveillance Program Speeds Detection of Colorectal Neoplasia. Gastroenterology, 139 pp. 1918-1926.
    [10.1053/j.gastro.2010.08.005] [10.1053/j.gastro.2010.08.005] [Scopus]
  • Le Leu, R.K., Hu, Y., Brown, I.L., Woodman, R.J. and Young, G.P. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2) pp. 246-251.
    [10.1093/carcin/bgp197] [10.1093/carcin/bgp197] [Scopus]
  • Martin, J.E., Hu, Y., Le Leu, R.K. and Young, G.P. (2010). R-flurbiprofen suppresses distal non-mucin-producing colorectal tumours in azoxymethane treated rats, without suppressing eicosanoid production. American Journal of Physiology-Gastrointestinal and Liver Physiology, 298 pp. G860-G864.
    [10.1152/ajpgi.00330.2009] [10.1152/ajpgi.00330.2009] [Scopus]
  • Wilson, C., Flight, I., Zajac, I., Turnbull, D., Young, G.P., Cole, S.R., et al. (2010). Protocol for population testing of an internet-based Personalised Decision Support system for colorectal cancer screening. BMC Medical Informatics and Decision Making, pp. 1-8.
    [10.1186/1472-6947-10-50] [10.1186/1472-6947-10-50] [Scopus]
  • Worthley, D.L., Whitehall, V.L., Buttenshaw, R.L., Irahara, N., Greco, S.A., Ramsnes, I., et al. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29 pp. 1653-1663.
    [10.1038/onc.2009.449] [10.1038/onc.2009.449] [Scopus]
  • Zajac, I., Whibley, A., Cole, S.R., Byrne, D.T., Guy, J.R., Morcom, J.M., et al. (2010). Endorsement by the primary care practitioner consistently improves participation in screening for colorectal cancer: a longitudinal analysis. Journal of Medical Screening, 17 pp. 19-24.
    [10.1258/jms.2010.009101] [10.1258/jms.2010.009101] [Scopus]
  • Le Leu, R.K., Hu, Y., Brown, I.L. and Young, G.P. (2009). Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutrition & Metabolism, 6(11)
    [10.1186/1743-7075-6-11] [10.1186/1743-7075-6-11] [Scopus]
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2009). Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes. Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 677(1-2) pp. 27-32.
    [10.1016/j.mrgentox.2009.05.003] [10.1016/j.mrgentox.2009.05.003] [Scopus]
  • Beckmann, K.R., Olver, I.N., Roder, D., Foreman, L.M., Young, G.P. and Wilson, B. (2009). Patient and carer perceptions of cancer care in South Australia. Australian Health Review, 33(4) pp. 645-655.
    [10.1071/AH090645] [Scopus]
  • Duncan, A., Wilson, C., Cole, S.R., Mikocka-Walus, A., Turnbull, D. and Young, G.P. (2009). Demographic associations with stage of readiness to screen for colorectal cancer. Health Promotion Journal of Australia, 20(1) pp. 7-12.
    [Scopus]
  • Walsh, M., Buchanan, D.D., Walters, R., Roberts, A., Arnold, S., McKeone, D., et al. (2009). Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia : the importance of pathology review and pedigree analysis. Familial Cancer, 8(4) pp. 313-323.
    [10.1007/s10689-009-9238-8] [10.1007/s10689-009-9238-8] [Scopus]
  • Wigg, A.J., Barritt, G.J., Young, G.P. and Phillips, J.W. (2009). Inhibition of oxidative stress and apoptosis enables extended maintenance of integrity and function of isolated hepatocytes in suspension. Journal of Gastroenterology and Hepatology, 24(6) pp. 1082-1088.
    [10.1111/j.1440-1746.2009.05798.x] [10.1111/j.1440-1746.2009.05798.x] [Scopus]
  • Worthley, D., Le Leu, R.K., Whitehall, V.L., Conlon, M., Christophersen, C., Belobrajdic, D.P., et al. (2009). A human, double-blind, placebo-controlled, cross-over trial of prebiotic, probiotic and synbiotic supplementation: effects on luminal, inflammatory, epigenetic and epithelial biomarkers of colorectal cancer. American Journal of Clinical Nutrition, 90(3) pp. 578-586.
    [10.3945/ajcn.2009.28106] [10.3945/ajcn.2009.28106] [Scopus]
  • Worthley, D.L., Ruszkiewicz, A.R., Davies, R., Moore, S., Nivison-Smith, I., To, B., et al. (2009). Human gastrointestinal neoplasia-associated myofibroblasts can develop from bone marrow-derived cells following allogeneic stem cell transplantation. Stem Cells, 27(6) pp. 1463-1468.
    [10.1002/stem.63] [10.1002/stem.63] [Scopus]
  • Lapointe, L.C., Dunne, R., Brown, G.S., Worthley, D., Molloy, P.L., Wattchow, D.A., et al. (2008). Map of differential transcript expression in the normal human large intestine. Physiological Genomics, 33(1) pp. 50-64.
    [10.1152/physiolgenomics.00185.2006] [10.1152/physiolgenomics.00185.2006] [Scopus]
  • Hu, Y., McIntosh, G.H., Le Leu, R.K., Woodman, R.J. and Young, G.P. (2008). Suppression of Colorectal Oncogenesis by Selenium-Enriched Milk Proteins: Apoptosis and K-ras Mutations. Cancer Research, 68(12) pp. 4936-4944.
    [10.1158/0008-5472.CAN-07-6042] [10.1158/0008-5472.CAN-07-6042] [Scopus]
  • Hu, Y., Le Leu, R.K., Belobrajdic, D. and Young, G.P. (2008). The potential of sphingomyelin as a chemopreventive agent in AOM-induced colon cancer model: wild-type and p53+/- mice. Molecular Nutrition and Food Research, 52(5) pp. 558-566.
    [10.1002/mnfr.200700258] [10.1002/mnfr.200700258] [Scopus]
  • Clarke, J.M., Topping, D.L., Bird, A.R., Young, G.P. and Cobiac, L. (2008). Effects of high-amylose maize starch and butyrylated high-amylose maize starch on azoxymethane-induced intestinal cancer in rats. Carcinogenesis, 29(11) pp. 2190-2194.
    [10.1093/carcin/bgn192] [10.1093/carcin/bgn192] [Scopus]
  • McIntosh, G.H., Dunshea, F.R., Mckenna, T.E., Walker, G., Hu, Y., Heard, J.W., et al. (2008). A dairy source of organic selenium for health and well-being. Food Australia, 60(4) pp. 132-134.
    [Scopus]
  • Wilson, C., Flight, I., Hart, E., Turnbull, D., Cole, S.R. and Young, G.P. (2008). Internet access for delivery of health information to South Australians older than 50. Australian and New Zealand Journal of Public Health, 32(2) pp. 174-176.
    [10.1111/j.1753-6405.2008.00196.x] [Scopus]
  • Uglietta, R., Doyle, P., Walker, G.P., Heard, J.W., Leddin, C.M., Stockdale, C.R., et al. (2008). Bioavailability of selenium from selenium-enriched milk assessed in the artificially reared neonatal pig. Nutrition and Dietetics, 65(s3) pp. S37-S40.
    [10.1111/j.1747-0080.2008.00259.x] [Scopus]
  • Sung, J.J.Y., Lau, J.Y.W., Young, G.P., Sano, Y., Chiu, H., Byeon, J., et al. (2008). Asia Pacific consensus recommendations for colorectal cancer screening. Gut, 57(8) pp. 1166-1176.
    [10.1136/gut.2007.146316] [10.1136/gut.2007.146316] [Scopus]
  • Ramakrishna, B.S., Subramanian, V., Mohan, V., Sebastian, B.K., Young, G.P., Farthing, M., et al. (2008). A randomized controlled trial of glucose versus amylase resistant starch hypo-osmolar oral rehydration solution for adult acute dehydrating diarrhea. PLoS One, 3(2) pp. e1587.
    [10.1371/journal.pone.0001587] [10.1371/journal.pone.0001587] [Scopus]
  • Bampton, P.A., Sandford, J.J. and Young, G.P. (2007). Achieving long-term compliance with colonoscopic surveillance guidelines for patients at increased risk of colorectal cancer in Australia. International Journal of Clinical Practice, 61(3) pp. 510-513.
    [10.1111/j.1742-1241.2006.01158.x] [10.1111/j.1742-1241.2006.01158.x] [Scopus]
  • Cole, S.R., Smith, A., Wilson, C., Turnbull, D., Esterman, A.J. and Young, G.P. (2007). An advance notification letter increases participation in colorectal cancer screening. Journal of Medical Screening, 14(2) pp. 73-75.
    [10.1258/096914107781261927] [10.1258/096914107781261927] [Scopus]
  • Heard, J.W., stockdale, C.R., Walker, G.P., Leddin, C.M., Dunshea, F.R., McIntosh, G.H., et al. (2007). Increasing Selenium Concentration in Milk: Effects of Amount of Selenium from Yeast and Cereal Grain Supplements. Journal of Dairy Science, 90(9) pp. 4117-4127.
    [10.3168/jds.2006-800] [10.3168/jds.2006-800] [Scopus]
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2007). Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac. Cancer Letters, 248(2) pp. 234-244.
    [10.1016/j.canlet.2006.07.009] [10.1016/j.canlet.2006.07.009] [Scopus]
  • Young, G.P. and Cole, S.R. (2007). New stool screening tests for colorectal cancer. Digestion, 76(1) pp. 26-33.
    [10.1159/000108391] [10.1159/000108391] [Scopus]
  • Winawer, S.J., Classen, M., Lambert, R., Fried, M., Dite, P., Goh, K.L., et al. (2007). Colorectal cancer screening: practice guideline (short version) World Gastroenterology News, 12(2) pp. 17-22.
    [Web Link]
  • Le Leu, R.K., Brown, I.L., Hu, Y., Morita, T., Esterman, A.J. and Young, G.P. (2007). Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis, 28(2) pp. 240-245.
    [10.1093/carcin/bgl245] [10.1093/carcin/bgl245] [Scopus]
  • Le Leu, R.K., Brown, I.L., Hu, Y., Esterman, A.J. and Young, G.P. (2007). Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biology and Therapy, 6(10) pp. 1621-1626.
    [Scopus] [Web Link]
  • Worthley, D., Mullighan, C.G., Dean, M.M., Gordon, D.L., Phillips, P., Heatley, S., et al. (2007). Mannose-binding lectin deficiency does not increase the prevalence of Helicobacter pylori seropositivity. European Journal of Gastroenterology and Hepatology, 19(2) pp. 147-152.
    [10.1097/MEG.0b013e3280106729] [10.1097/MEG.0b013e3280106729] [Scopus]
  • Raghupathy, P., Ramakrishna, B.S., Oommen, S.P., Ahmed, M.S., Priyaa, G., Dziura, J., et al. (2006). Amylase-resistant starch as adjunct to oral rehydration therapy in children with diarrhea. Journal of Pediatric Gastroenterology and Nutrition, 42(4) pp. 362-368.
    [10.1097/01.mpg.0000214163.83316.41] [10.1097/01.mpg.0000214163.83316.41] [Scopus]
  • Baker, G., Fraser, R.J. and Young, G.P. (2006). Subtypes of functional dyspepsia. World Journal of Gastroenterology, 12(17) pp. 2667-2671.
    [Scopus] [Web Link]
  • Smith, A.T., Young, G.P., Cole, S.R. and Bampton, P. (2006). Comparison of a brush-sampling fecal immunochemical test for hemoglobin with a sensitive guaiac-based fecal occult blood test in detection of colorectal neoplasia. Cancer, 107(9) pp. 2152-2159.
    [10.1002/cncr.22230] [10.1002/cncr.22230] [Scopus]
  • Worthley, D., Smith, A.T., Bampton, P., Cole, S.R. and Young, G.P. (2006). Many participants in fecal occult blood test population screening have a higher-than-average risk for colorectal cancer. European Journal of Gastroenterology and Hepatology, 18(10) pp. 1079-1083.
    [10.1097/01.meg.0000231754.35340.fa] [10.1097/01.meg.0000231754.35340.fa] [Scopus]
  • Worthley, D., Cole, S.R., Esterman, A.J., Mehaffey, S.J., Roosa, N.M., Smith, A.T., et al. (2006). Screening for colorectal cancer by faecal occult blood test: why people choose to refuse. Internal Medicine Journal, 36(9) pp. 607-610.
    [10.1111/j.1445-5994.2006.01155.x] [10.1111/j.1445-5994.2006.01155.x] [Scopus]
  • Subramanya, S., Ramakrishna, B.S., Binder, H.J., Farthing, M. and Young, G.P. (2006). Evaluation of oral rehydration solution by whole-gut perfusion in rats: effect of osmolarity, sodium concentration and resistant starch. Journal of Pediatric Gastroenterology and Nutrition, 43(5) pp. 568-575.
    [10.1097/01.mpg.0000239998.43141.b2] [Scopus]
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2005). Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice. International Journal of Cancer, 116(6) pp. 870-875.
    [10.1002/ijc.21107] [10.1002/ijc.21107] [Scopus]
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2005). Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours. International Journal of Cancer, 115(4) pp. 561-567.
    [10.1002/ijc.20876] [10.1002/ijc.20876] [Scopus]
  • Bampton, P., Sandford, J.J., Cole, S.R., Smith, A., Morcom, J., Cadd, B., et al. (2005). Interval faecal occult blood testing in a colonoscopy based screening programme detects additional pathology. Gut, 54(6) pp. 803-806.
    [10.1136/gut.2004.043786] [10.1136/gut.2004.043786] [Scopus]
  • Le Leu, R.K., Brown, I., Hu, Y., Bird, A.R., Jackson, M., Esterman, A.J., et al. (2005). A synbiotic combination of resistant starch and Bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged dells in rat colon. Journal of Nutrition, 135(5) pp. 996-1001.
    [Scopus]
  • Luke, C., Koczwara, B., Moore, J., Olver, I., Penniment, M., Pittman, K., et al. (2005). Treatment and survival from colorectal cancer: the experience of patients at South Australia teaching hospitals between 1980 and 2002. Clinical Oncology, 17(5) pp. 372-381.
    [10.1016/j.clon.2005.04.005] [10.1016/j.clon.2005.04.005] [Scopus]
  • Young, G.P., Hu, Y., Le Leu, R.K. and Nyskohus, L. (2005). Dietary fibre and colorectal cancer : a model for environment - gene interactions. Molecular Nutrition and Food Research, 49(6) pp. 571-584.
    [10.1002/mnfr.200500026] [10.1002/mnfr.200500026] [Scopus]
  • Young, G.P. (2004). Fecal immunochemical tests (FIT) vs. office-based guaiac fecal occult test (FOBT) Practical Gastroenterology, 28(6) pp. 46-56.
    [Scopus] [Web Link]
  • Young, G.P. and Le Leu, R.K. (2004). Resistant starch and colorectal neoplasia. Journal of AOAC International, 87(3) pp. 775-786.
    [Scopus]
  • Young, G.P., Bampton, P., Cole, S.R., Morcom, J., Smith, A., Turnbull, D., et al. (2004). Screening for colorectal cancer. Public Health Bulletin South Australia, 1 pp. 22-25.
    [Web Link]
  • Michael, M.Z., O'Connor, S.M., Van Holst Pellekaan, N.G., Young, G.P. and James, R.J. (2003). Reduced accumulation of specific MicroRNAs in colorectal neoplasia. Molecular Cancer Research, 1(12) pp. 882-891.
    [Scopus]
  • Le Leu, R.K., Brown, I.L., Hu, Y. and Young, G.P. (2003). Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats. Carcinogenesis, 24(8) pp. 1347-1352.
    [10.1093/carcin/bgg098] [10.1093/carcin/bgg098] [Scopus]
  • Cole, S.R., Young, G.P., Esterman, A.J., Cadd, B. and Morcom, J. (2003). A randomised trial of the impact of new faecal haemoglobin test technologies on population participation in screening for colorectal cancer. Journal of Medical Screening, 10(3) pp. 117-122.
    [10.1258/096914103769011003] [Scopus]
  • Wong, B.C.Y., Wong, W.M., Cheung, K.L., Tong, T.S.M., Rozen, P., Young, G.P., et al. (2003). A sensitive guaiac faecal occult blood test is less useful than an immunochemical test for colorectal cancer screening in a Chinese Population. Alimentary Pharmacology and Therapeutics, 18(9) pp. 941-946.
    [10.1046/j.1365-2036.2003.01783.x] [10.1046/j.1365-2036.2003.01783.x] [Scopus]
  • Young, G.P., St John, J.B., Cole, S.R., Bielecki, B.E., Pizzey, C., Sinatra, M.A., et al. (2003). Prescreening evaluation of a brush-based faecal immunochemical test for haemoglobin. Journal of Medical Screening, 10(3) pp. 123-128.
    [10.1258/096914103769011012] [Scopus]
  • Wong, W.M., Lam, S.K., Cheung, K.L., Tong, T.S.M., Rozen, P., Young, G.P., et al. (2003). Evaluation of an automated immunochemical fecal occult blood test for colorectal neoplasia detection in a Chinese population. Cancer, 97(10) pp. 2420-2424.
    [10.1002/cncr.11369] [10.1002/cncr.11369] [Scopus]
  • Bampton, P., Sandford, J.J. and Young, G.P. (2002). Applying evidence-based guidelines improves use of colonoscopy resources in patients with a moderate risk of colorectal neoplasia. Medical Journal of Australia, 176(4) pp. 155-157.
    [Scopus] [Web Link]
  • Cole, S.R., Young, G.P., Byrne, D.T., Guy, J.R. and Morcom, J.M. (2002). Participation in screening for colorectal cancer based on a faecal occult blood test is improved by endorsement by the primary care practitioner. Journal of Medical Screening, 9(4) pp. 147-152.
    [10.1136/jms.9.4.147] [10.1136/jms.9.4.147] [Scopus]
  • Hu, Y., Martin, J.E., Le Leu, R.K. and Young, G.P. (2002). The colonic response to genotoxic carcinogens in the rat : regulation by dietary fibre. Carcinogenesis, 23(7) pp. 1131-1137.
    [10.1093/carcin/23.7.1131] [Scopus]
  • Le Leu, R.K., Hu, Y. and Young, G.P. (2002). Effects of resistant starch and nonstarch polysaccharides on colonic luminal environment and genotoxin-induced apoptosis in the rat. Carcinogenesis, 23(5) pp. 713-719.
    [10.1093/carcin/23.5.713] [Scopus]
  • Young, G.P. and Le Leu, R.K. (2002). Preventing cancer: dietary lifestyle or clinical intervention? Asia Pacific Journal of Clinical Nutrition On Line, 11(S3) pp. S618-S631.
    [10.1046/j.0964-7058.2002.00337.x] [Scopus]
  • Young, G.P., St John, J.B., Winawer, S.J., Rozen, P. and Who Omed Fobt Screening Comm, (2002). Choice of fecal occult blood tests for colorectal cancer screening: recommendations based on performance characteristics in population studies. American Journal of Gastroenterology, 97(10) pp. 2499-2507.
    [10.1016/S0002-9270(02)04404-0] [10.1111/j.1572-0241.2002.06046.x] [Scopus]
  • Cole, S.R. and Young, G.P. (2001). Effect of dietary restriction on particpation in faecal occult blood test screening for colorectal cancer. Medical Journal of Australia, 175 pp. 195-198.
  • Hebbard, G., Gailer, J. and Young, G.P. (2001). Alternatives to cisapride. Australian Prescriber, 24(5) pp. 110-112.
    [Web Link]
  • Bampton, P., Young, G. and St John, J. (2000). Screening for colorectal cancer saves lives. Medical Journal of Australia, 172(12) pp. 576-577.
    [Web Link]
  • Young, G., Ward, P., Bayley, N., Gordon, D., Higgins, G., Trapani, J., et al. (1985). Antibiotic-associated colitis due to Clostridium difficile: double-blind comparison of vancomycin with bacitracin. Gastroenterology, 89(5) pp. 1038-1045.
    [PubMed]
  • Worthley, D.L., Whitehall, V.L., Buttenshaw, R.L., Irahara, N., Greco, S.A., Ramsnes, I., et al. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29 pp. 1653-1663.
    [10.1038/onc.2009.449] [10.1038/onc.2009.449] [Scopus]
  • Le Leu, R.K., Hu, Y., Brown, I.L., Woodman, R.J. and Young, G.P. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2) pp. 246-251.
    [10.1093/carcin/bgp197] [10.1093/carcin/bgp197] [Scopus]
  • Le Leu, R.K., Hu, Y., Brown, I.L. and Young, G.P. (2009). Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutrition & Metabolism, 6(11)
    [10.1186/1743-7075-6-11] [10.1186/1743-7075-6-11] [Scopus]
  • Ramakrishna, B.S., Subramanian, V., Mohan, V., Sebastian, B.K., Young, G.P., Farthing, M., et al. (2008). A randomized controlled trial of glucose versus amylase resistant starch hypo-osmolar oral rehydration solution for adult acute dehydrating diarrhea. PLoS One, 3(2) pp. e1587.
    [10.1371/journal.pone.0001587] [10.1371/journal.pone.0001587] [Scopus]
  • Hu, Y., McIntosh, G.H., Le Leu, R.K., Woodman, R.J. and Young, G.P. (2008). Suppression of Colorectal Oncogenesis by Selenium-Enriched Milk Proteins: Apoptosis and K-ras Mutations. Cancer Research, 68(12) pp. 4936-4944.
    [10.1158/0008-5472.CAN-07-6042] [10.1158/0008-5472.CAN-07-6042] [Scopus]
  • Lapointe, L.C., Dunne, R., Brown, G.S., Worthley, D., Molloy, P.L., Wattchow, D.A., et al. (2008). Map of differential transcript expression in the normal human large intestine. Physiological Genomics, 33(1) pp. 50-64.
    [10.1152/physiolgenomics.00185.2006] [10.1152/physiolgenomics.00185.2006] [Scopus]
  • Hu, Y., Le Leu, R.K. and Young, G.P. (2007). Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac. Cancer Letters, 248(2) pp. 234-244.
    [10.1016/j.canlet.2006.07.009] [10.1016/j.canlet.2006.07.009] [Scopus]
  • Le Leu, R.K., Brown, I.L., Hu, Y., Morita, T., Esterman, A.J. and Young, G.P. (2007). Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis, 28(2) pp. 240-245.
    [10.1093/carcin/bgl245] [10.1093/carcin/bgl245] [Scopus]
  • Cole, S.R., Smith, A., Wilson, C., Turnbull, D., Esterman, A.J. and Young, G.P. (2007). An advance notification letter increases participation in colorectal cancer screening. Journal of Medical Screening, 14(2) pp. 73-75.
    [10.1258/096914107781261927] [10.1258/096914107781261927] [Scopus]
  • Young, G.P., Rozen, P. and Levin, B. (2006). How should we screen for early colorectal neoplasia? In Paul Rozen, Graeme Young, Bernard Levin, Stephen Spann, ed. Colorectal Cancer in Clinical Practice: Prevention, Early Detection and Management. 2nd ed. London, UK: Taylor and Francis, pp. 97-129.

Professional and community engagement

In terms of leadership and peer processes, he is now Chairman of the Governing Council (board) of the FCIC. He has participated in and/or chairs national committees or boards including the Australian National Bowel Cancer Screening Program, NHMRC, and National Cancer Control Initiative. He has served as a council member of the Gastroenterological Society of Australia for 12 years. He has advised several international research bodies (including US National Cancer Institute), organisations involved in management of cancer (e.g. WEO, UICC) and biotechnology companies. He is a founding Board Member of the International Digestive Cancer Alliance and is the Chair of the World Endoscopy Organization (WEO) Colorectal Cancer Screening Committee.

He has advised health authorities in Australia, and a number of countries around the world including New Zealand, United Kingdom, Canada, the United States, Netherlands and other countries on aspects of prevention of colorectal cancer. In 2012, he was invited by the Bill and Melinda Gates Foundation to establish a global process re-examining the role of zinc therapy in diarrhoea and malnutrition in developing countries.

Expertise for media contact

Subject Titles

  • Cancer
  • Gastroenterology
  • Nutrition

Interests

  • Colorectal Cancer particularly prevention, population screening, risk profiling and genetics
  • Intestinal Epithelial Biology particularly effect of dietary factors
  • Nutrition
  • Chemoprevention
  • Gastroenterology

Contact

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Phone: +61 8 84042841
Email:
Location: Flinders Centre for Innovation in Cancer (3L:100)
Postal address: GPO Box 2100, Adelaide 5001, South Australia
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