Biography

I completed my undergraduate and post-graduate studies at Flinders University, and then moved overseas and I held full-time tenured
positions at Carnegie-Mellon University, Pittsburgh, Heriot-Watt University, Edinburgh, Imperial College, London and UIB, Spain before
returning to Flinders as Chair of Computer Systems Engineering. I have also held visiting positions at Bonn University, in Germany, and
the University of the Witwatersrand, in Johannesburg, South Africa.
I also started my own company, and designed a VLSI chip implementing a Zero-Tree wavelet video compression algorithm. This work
produced three US patents, and the company was sold to MediaVision, in Silicon Valley.

Qualifications

BSc(Hons) Flinders University
PhD Flinders University

Honours, awards and grants

FIEAust (Fellow, Institute of Engineers Australia)

Key responsibilities

I run the Embedded Systems and Bio-Informatics research groups in the School of Computer Science, Engineering and Mathematics.

Topic Coordinator:

Topic Lecturer:

Research interests

My main research interests are in the area of Integrated Circuit design, Computer Architecture, Image and Video processing and Bio-informatics.
I was one of the first researchers to see the advantages of the wavelet transform for Image Processing, and developed a new class of
image and video compression algorithms, the Zero-Tree coders. These algorithms have proven to be the most efficient image and video
compression algorithms, and my work has been incorporated into the MPEG4 standard, and has been granted several US patents.
In Java, we have developed an incremental tokenization scheme for the J2ME/J2SE method call and storage instructions, reducing class
size by one-half, and execution speed of method calls by a factor of 10-40.
In Bio-informatics, we have developed a new algorithm for Genomic and Proteomic sequence alignment, DASH, which performs 10X
faster than the industry standard BLAST with greater sensitivity. I am currently involved in an Algae bio-fuels project working on
short-read shotgun genome assembly and determining the key genes for bio-fuel production. This work has produced several
international patent applications.

Publications

  • Gardner-Stephen, P.M. and Knowles, G.P. (2009). DASH: Searching Compressed DNA: Creating and Searching Compact Databases for The Genomic Era. Germany: VDM Verlag Dr. Müller.
  • Bessell, T.J., Randell, M.S., Knowles, G.P. and Hobbs, D.A. (2006). Connecting people with the environment: A new accessible wireless remote control. In Connecting people and community through technology : proceedings of the of the ARATA national conference 2006. Australian Rehabilitation & Assistive Technology Association. ARATA National Conference 2006: Connecting People and Community Through Technology. Fremantle, WA. Oct 2006.
    [Web Link]
  • Knowles, G.P. and Donnelley, M.W. (2005). Reducing the fracture miss rate: aiding diagnosis through image processing [abstract 13] In ANZORS 11th Annual Scientific Meeting. ANZORS 11th Annual Scientific Meeting. Perth, WA. Oct 2005.
    [Web Link]
  • Knowles, G.P. (2003). Real-time hardware architectures for the bi-orthogonal wavelet transform (Abstract) In Kehtarnavaz, NLaplante, P, ed. Real-time imaging VII. USA: International Society for Optical Engineering. Proc. SPIE-IST & T Electronic Imaging. Santa Clara, CA. Jan 2003, pp. 102-109.
    [10.1117/12.477481] [10.1117/12.477481] [Scopus]
  • Ball, A., Moore, B., Knowles, G. and Qin, J. (2011). Nucleic acid molecule. Patent: 8034603 B2 United States of America. Patent owner: Andrew Ball, Robert Moore, Gregory Knowles, Jian Qin
    [Web Link]
  • Ball, A., Moore, B., Knowles, G. and Qin, J. (2011). Nucleic acid molecule encoding triterpenoid synthase. Patent: WO 2011/032213 A1 Numerous (World Intellecrtual Property Organisation) PCT. Patent owner: WWCC LIMITED
    [Web Link] [Web Link]
  • Knowles, G.P. (2009). A complete classification of short symmetric-antisymmetric multiwavelets. In G.P. Curbera, G. Mockenhaupt, W.J. Ricker, ed. Vector measures, integration and related topics. Germany: Birkhauser Verlag,. Vector Measures, Integration and Related Topics. Eichstaett (Germany) pp. 271-283.
  • Tsakiris, N. and Knowles, G.P. (2008). Enabling gigabit IP for intelligent systems. In Dimitrov, Simian, Mladenov, Jordanova, Mastorakis, ed. Proceedings of the 10th WSEAS International Conference on Mathematical Methods and Computational Techniques in Electrical Engineering. Wisconsin, USA: WSEAS. 10th WSEAS International Conference on Mathematical Methods and Computational Techniques in Electrical Engineering. Sofia, Bulgaria. May 2008, pp. 162-166.
    [Web Link] [Web Link]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2007). NP3: A New DNA Compression Algorithm. In Prof. Tuan Pham, ed. Proceedings of the 3rd WSEAS International Conference on Mathematical Biology and Ecology (MABE'07) Wisconsin, USA: World Scientific and Engineering Academy and Society (WSEAS). 3rd WSEAS Int.Conf. on MATHEMATICAL BIOLOGY and ECOLOGY (MABE'07) Gold Coast, QLD. Jan 2007.
  • Haggett, S.R., Knowles, G.P. and Bignell, G.H. (2007). Tokenisation of class files for an embedded java processor. In Proceedings of the 6th IEEE/ACIS International Conference on Computer and Information Science. Los Alamitos, USA: IEEE Computer Society/ACIS. 6th IEEE/ACIS International Conference on Computer and Information Science. Melbourne, SA. Jul 2007, pp. 375-381.
    [10.1109/ICIS.2007.181] [10.1109/ICIS.2007.181] [Scopus] [Web Link]
  • Knowles, G.P., Bignell, G.H. and Haggett, S.R. (2005). A pure java-card installer and its verification. In P. A. Venkatachalam, ed. International Conference on Intelligent Systems 2005 (ICIS 2005) Kuala Lumpur, Malaysia: IEEE Malaysia. International Conference on Intelligent Systems 2005 (ICIS 2) Kuala Lumpur, Malaysia. Dec 2005.
  • Knowles, G.P. and Donnelley, M.W. (2005). Computer aided long bone fracture detection. In Proceedings of the 8h International Symposium on Signal Processing and its Applications. Los Alamitos, USA: IEEE. The Eighth International Symposium on Signal Processing and s. Sydney, Australia. Aug 2005, pp. 175-178.
    [10.1109/ISSPA.2005.1580224] [Scopus]
  • Knowles, G.P. and Donnelley, M.W. (2005). Automated bone fracture detection. In J. M. Fitzpatrick, J. M. Reinhardt, ed. Proceedings of SPIE Progress in Biomedical Optics and Imaging 2005. Belligham, USA: SPIE. SPIE Symposium on Medical Imaging 2005 Volume 5745. San Diego, pp. 955-966.
    [10.1117/12.594449] [10.1117/12.594449] [Scopus]
  • Knowles, G.P. and Tsakaris, N. (2005). A comparison of Hardware Architectures for the JPEG2000 Wavelet Transform. In Prof. P. A. Venkatachalam (organizing secretary), ed. International Conference on Intelligent Systems 2005 (ICIS 2005) Kuala Lumpur: Electrical & Electronic Engineering Programme. International Conference on Intelligent Systems 2005 (ICIS 2005) Kuala Lumpur, Malaysia.
  • Knowles, G.P. and Gardner-Stephen, P.M. (2004). DASH: localising dynamic programming for order of magnitude faster, accurate sequence alignment. In Proceedings of the IEEE Computational Systems Bioinformatics Conference. Los Alamitos, USA: IEEE Computer Society. Computational Systems Bio Infomatics (CSB) 2004. Stanford, USA, pp. 732-735.
    [Scopus]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2004). DASH: a new high speed genomic sequence search and alignment tool. In WSEAS Transactions on Computers: Proceedings of the 4th WSEAS International Conference on Mathematics and Computers in Biology and Chemistry. [Athens, Greece]: World Scientific and Engineering Academy and Society (WSEAS). 4th WSEAS International Conference on Mathematics and Computers in Biology and Chemistry. Tenerife, Spain, pp. 59-64.
  • Knowles, G.P. and Gardner-Stephen, P.M. (2004). A new hardware architecture for genomic and proteomic sequence alignment. In V Markstein, ed. Proceedings of the IEEE Computational Systems Bioinformatics Conference. Los Alamitos, USA: IEEE. Computational Systems Bio Informatics (CSB) 2004. Stanford, USA, pp. 730-731.
    [Scopus]
  • Knowles, G.P. and Gardner-Stephen, P.M. (2003). A novel architecture for genomic sequence searching and alignment. In Omondi, ASedukhin, S, ed. Advances in Computer Systems Architecture: Lecture Notes in Computer Science. Germany: Springer-Verlag. The Eighth Asia-Pacific Computer Systems Architecture Conference. Aizu, Japan. Sep 2003, pp. 180-192.
    [10.1007/13479] [Scopus]
  • Van Beurden, J., Knowles, G.P. and Bignell, G.H. (2003). An extended CAP file to support high performance embedded java. In WSEAS TRANSACTIONS ON COMPUTERS: proceedings of the 2nd WSEAS International Conference on Electronics, Control and Signal Processing. Stevens Point, Wisconsin, USA: World Scientific and Engineering Academy and Society (WSEAS). 2nd WSEAS International Conference on Electronics, Control and Signal Processing. Guthrie Theatre (Building 6), DAB, pp. 128-135.
  • Haggett, S.R. and Knowles, G.P. (2012). Tokenisation and Compression of Java Class Files. Journal of Systems Architecture, 58(1) pp. 1-12.
    [10.1016/j.sysarc.2011.09.002] [Scopus]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2007). NP3: Cooperative Compression Of Clustered DNA Databases And Their Indexes. WSEAS Transactions on Biology and Biomedicine, 3(7) pp. 565-572.
  • Knowles, G.P. and Gardner-Stephen, P.M. (2006). DASH, DASH-H: Software and Hardware for Sequence Alignment. WSEAS Transactions on Biology and Biomedicine, 3(1) pp. 37-42.
    [Web Link]
  • Knowles, G.P. and Freeman, D. (2004). Novel architectures for the JPEG2000 block coder. Journal of Electronic Imaging, 13(4) pp. 897-906.
    [10.1117/1.1785802] [10.1117/1.1785802] [Scopus]
  • Knowles, G.P. (2002). Hardware architectures for the orthogonal and biorthogonal wavelet transform. VLSI Design, 15(2) pp. 499-506.
    [10.1080/1065514021000012110] [10.1080/1065514021000012110] [Scopus]
  • Knowles, G.P. (2009). A complete classification of short symmetric-antisymmetric multiwavelets. In G.P. Curbera, G. Mockenhaupt, W.J. Ricker, ed. Vector measures, integration and related topics. Germany: Birkhauser Verlag,. Vector Measures, Integration and Related Topics. Eichstaett (Germany) pp. 271-283.
  • Tsakiris, N. and Knowles, G.P. (2008). Enabling gigabit IP for intelligent systems. In Dimitrov, Simian, Mladenov, Jordanova, Mastorakis, ed. Proceedings of the 10th WSEAS International Conference on Mathematical Methods and Computational Techniques in Electrical Engineering. Wisconsin, USA: WSEAS. 10th WSEAS International Conference on Mathematical Methods and Computational Techniques in Electrical Engineering. Sofia, Bulgaria. May 2008, pp. 162-166.
    [Web Link] [Web Link]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2007). NP3: A New DNA Compression Algorithm. In Prof. Tuan Pham, ed. Proceedings of the 3rd WSEAS International Conference on Mathematical Biology and Ecology (MABE'07) Wisconsin, USA: World Scientific and Engineering Academy and Society (WSEAS). 3rd WSEAS Int.Conf. on MATHEMATICAL BIOLOGY and ECOLOGY (MABE'07) Gold Coast, QLD. Jan 2007.
  • Haggett, S.R., Knowles, G.P. and Bignell, G.H. (2007). Tokenisation of class files for an embedded java processor. In Proceedings of the 6th IEEE/ACIS International Conference on Computer and Information Science. Los Alamitos, USA: IEEE Computer Society/ACIS. 6th IEEE/ACIS International Conference on Computer and Information Science. Melbourne, SA. Jul 2007, pp. 375-381.
    [10.1109/ICIS.2007.181] [10.1109/ICIS.2007.181] [Scopus] [Web Link]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2009). DASH: Searching Compressed DNA: Creating and Searching Compact Databases for The Genomic Era. Germany: VDM Verlag Dr. Müller.
  • Haggett, S.R. and Knowles, G.P. (2012). Tokenisation and Compression of Java Class Files. Journal of Systems Architecture, 58(1) pp. 1-12.
    [10.1016/j.sysarc.2011.09.002] [Scopus]
  • Gardner-Stephen, P.M. and Knowles, G.P. (2007). NP3: Cooperative Compression Of Clustered DNA Databases And Their Indexes. WSEAS Transactions on Biology and Biomedicine, 3(7) pp. 565-572.
  • Knowles, G.P. and Gardner-Stephen, P.M. (2006). DASH, DASH-H: Software and Hardware for Sequence Alignment. WSEAS Transactions on Biology and Biomedicine, 3(1) pp. 37-42.
    [Web Link]
  • Knowles, G.P. and Freeman, D. (2004). Novel architectures for the JPEG2000 block coder. Journal of Electronic Imaging, 13(4) pp. 897-906.
    [10.1117/1.1785802] [10.1117/1.1785802] [Scopus]
  • Knowles, G.P. (2002). Hardware architectures for the orthogonal and biorthogonal wavelet transform. VLSI Design, 15(2) pp. 499-506.
    [10.1080/1065514021000012110] [10.1080/1065514021000012110] [Scopus]

Expertise for media contact

Subject Titles

  • Engineering - Computer Systems
  • Images/Imaging

Interests

  • VLSI and Embedded Systems
  • Digital Image Processing

Contact

Add to address book
Phone: -
Email:
Location: - (-)
Postal address: GPO Box 2100, Adelaide 5001, South Australia
MACO login

inspiring achievement