Position

Web Supervisor & Academic Status
Renal

Biography

Jonathan Gleadle is a Consultant Nephrologist at Flinders Medical Centre and Professor of Medicine at Flinders University and is continuing to pursue his activities in clinical medicine, teaching and research.  For the preceeding five years he was the University Lecturer in Nephrology and General Medicine at Oxford University.  He is currently heading an independent Research Group at Flinders focusing on the regulation of gene expression and microRNAs by oxygen and its implications for renal disease and renal cancer.  His research interests have focussed on the sensing of oxygen by cells; a topic with broad relevance to the understanding of cellular physiology, ischaemic disease and cancer.

Qualifications

BM BCh, MA (Oxon), DPhil (Oxon), FRCP(UK), FRACP

Teaching interests

Renal Medicine
History and Examination
Author of 'History and Examination at a Glance'
Author renal chapters 'Medicine at a Glance'
Author ' Preparation for the FRACP; Questions and Answers'

Research expertise

  • Biochemistry and cell biology
  • Clinical sciences
  • Molecular biology

Research interests

Research over the last five years has focussed on the clinical relevance of microRNAs in renal disease and renal cancer and on molecular and cellular responses to oxygen. The sensing of oxygen by cells has broad relevance to the understanding of cellular physiology, renal failure, ischaemic disease and cancer. Recent clinical studies have also examined the clinical relevance of microRNAs to renal disease and viruses, the role of Cardiac MRI in renal patients, renal dysfunction following cardiac surgery and the use of novel surfaces to facilitate novel urine diagnostics and anti-infective strategies.

Supervisory interests

  • Exosomes
  • Hypoxia
  • MicroRNA
  • Oxygen
  • Oxygen-sensing
  • Renal failure
  • Renal transplantation
  • Responses to hypoxia

RHD research supervision

Current

Principal supervisor : Renal failure following cardiac surgery (1) ;

Associate supervisor : Diabetes and Renal Failure (1) ;

Completion

Principal supervisor : Hypoxia and MicroRNAs (1) ;

Associate supervisor : Cardiac MRI and renal disease (1) ;

Publications

  • Gleadle, J.M. and Ratcliffe, P.J. (2001). Hypoxia. In Encyclopedia of Life Sciences. Wiley: Wiley.
  • Gleadle, J.M., Yong, T.Y., Li, J., Tarafdar, S. and Wu, P.C.D. (2013). Passing the FRACP Written Examination: Questions and Answers. United States: John Wiley & Sons Inc.
    [Web Link]
  • Parnham, S., Gleadle, J.M., Leong, D.P.Y., Grover, S.K., bradbrook, C., Woodman, R.J., et al. (2015). Myocardial perfusion is impaired in renal transplant and liver transplant patients. In Proceedings of the 18th Annual SCMR Scientific Sessions. Journal of Cardiovascular Magnetic. 18th Annual SCMR Scientific Sessions. Nice, France. Feb 2015.
  • Parnham, S., Gleadle, J.M., Leong, D.P.Y., Grover, S.K., Perry, R., Bradbook, C., et al. (2015). Myocardial oxygenation is impaired in advanced chronic kidney disease and renal transplant patients. In Proceedings of the 18th Annual SCMR Scientific Sessions. Journal of Cardiovascular Magnetic Resonance. 18th Annual SCMR Scientific Sessions.
  • Parnham, S.F., Grover, S., bradbrook, C., Leong, D.P.Y., De Pasquale, C.G., Gleadle, J.M., et al. (2014). Myocardial oxygenation is reduced in end-stage renal failure: a novel blood oxygen level dependant (BOLD)-cardiac MRI study. In Journal of Cardiovascular Magnetic Resonance. 17th Annual Society for Cardiovascular Magnetic Resonance Scientific Sessions. New Orleans, USA. Jan 2014, pp. P184.
    [10.1186/1532-429X-16-S1-P184]
  • Parnham, S.F., Grover, S., bradbrook, C., Leong, D.P.Y., De Pasquale, C.G., Gleadle, J.M., et al. (2014). Reduced myocardial perfusion in post renal transplant population is not associated with aortic stiffness. In Journal of Cardiovascular Magnetic Resonance. 17th Annual Society for Cardiovascular Magnetic Resonance Scientific Sessions. New Orleans, USA. Jan 2014, pp. P226.
    [10.1186/1532-429X-16-S1-P226] [PubMed Central]
  • Parnham, S., Grover, S., bradbrook, C., Leong, D., DePasquale, C., Woodman, R.J., et al. (2013). Renal Transplant Patients Have Impaired Myocardial Perfusion Independent of the Degree of Left Ventricular Hypertrophy: a CMR Study. In Eur Heart J. ESC Congress 2013. Amsterdam, Netherlands. Aug 2013.
  • Parnham, S., Grover, S., bradbrook, C., Srinivasan, G., DePasquale, C., Woodman, R.J., et al. (2013). Myocardial perfusion is impaired in asymptomatic patients post renal transplantation. In J Cardiovascular Magnetic Resonance. 16th Annual SCMR Scientific Sessions. San Francisco, CA, USA. Jan 2013, pp. E68.
  • Parnham, S., Grover, S., bradbrook, C., Woodman, R.J., Gleadle, J. and Selvanayagam, J. (2013). Myocardial Perfusion is Impaired in Asymptomatic Patients Post Renal Transplantation. In Heart, Lung & Circulation. The Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting. Gold Coast. Aug 2013, pp. S188.
  • Parnham, S.F., Grover, S.K., De Pasquale, C.G., Leong, D.P.Y., Gleadle, J.M. and Selvanayagam, J.B. (2013). Myocardial Oxygenation is Reduced in End-Stage Renal Failure: A Novel Blood Oxygen Level Dependant (BOLD)-Cardiac MRI Study. In Circulation. American Heart Association (AHA) Conference. Dallas, Texas, USA. Nov 2013, pp. A16286.
    [Web Link]
  • Bennett, P.N., Miller, M., Woodman, R., Hill, K., Murray, S. and Gleadle, J. (2011). Satellite Dialysis Nurse-Performed Nutritional Screening Tool: A Randomised Control Trial. 39th Annual Renal Society of Australasia Conference. Adelaide, South Australia. Jun 2011.
    [Web Link]
  • Bennett, P.N., Miller, M., Woodman, R., Hill, K., Murray, S. and Gleadle, J. (2011). Improving health through nutrition screening by haemodialysis nurses. European Dialysis and Transplant Nurses Association 40th Annual Conference. Ljubljana, Slovenia. Sep 2011.
    [Web Link]
  • Tarafdar, S. and Gleadle, J.M. (2013). Bilateral kidney tumors and lung cysts. Kidney International, 83(2) pp. 337-338.
    [10.1038/ki.2012.366] [Scopus]
  • Li, J., Fang, D., Yong, T., Klebe, S., Juneja, R. and Gleadle, J.M. (2013). Transitional cell carcinoma in a renal allograft with BK nephropathy. Tranplant Infectious Disease, 15(6) pp. E270-E272.
    [10.1111/tid.12142] [Scopus]
  • Gleadle, J.M., Mole, D.R. and Pugh, C.W. (2006). Hypoxia-inducible factors: where, when and why? Kidney International, 69 pp. 15-17.
  • Gleadle, J.M. (2006). Early intervention in acute renal failure: Assessing fluid status is important. British Medical Journal, 333(7567) pp. 551.
  • Maxwell, P.H., Buckley, C., Gleadle, J.M. and Mason, P.D. (2001). Nasty shock after an anti-emetic. Nephrology Dialysis Transplantation, 16 pp. 1069-1072.
  • Gleadle, J.M. and Mason, P.D. (2000). Sirolimus vs azathioprine. Lancet, 356(9243) pp. 1768-1768.
  • Gleadle, J.M., Davies, D. and Altmann, P. (2000). Pulmonary, cardiac and renal syndrome. Nephrology Dialysis Transplantation, 15 pp. 731-732.
  • Hain, S.F., Gleadle, J.M. and Maisey, M.N. (1999). F-18 fluorodeoxyglucose PET in the diagnosis of vascular invasion in renal cell carcinoma. CLINICAL NUCLEAR MEDICINE, 24(10) pp. 819-820.
  • Gleadle, J.M. and Ratcliffe, P.J. (1998). Hypoxia and the regulation of gene expression. Trends in Molecular Medicine, 4(3) pp. 122-129.
  • Ratcliffe, P.J., Ebert, B.L., Ferguson, D.J.P., Firth, J.D., Gleadle, J.M., Maxwell, P.H., et al. (1995). State of the Art Lecture: Regulation of the erythropoietin gene. Nephrology Dialysis Transplantation, 10(Suppl 2) pp. 18-27.
  • Gleadle, J.M. (2012). F1000Prime Recommendation . A role for small RNAs in DNA double-strand break repair, Cell. 2012 Mar 30; 149(1):101-12.
  • Gleadle, J.M. (2011). F1000Prime Recommendation . Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2, Cell Metab. 2011 Nov 2; 14:647-57.
  • Gleadle, J.M. (2011). F1000Prime Recommendation . Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3, Genet. 2011 Jan; 43(1):60-5.
  • Gleadle, J.M. (2011). F1000Prime Recommendation. 160 as a novel target of the von Hippel-Lindau tumor suppressor, PLoS ONE. 2011; 6(2):e16975.
  • Gleadle, J.M. (2010). F1000Prime Recommendation . Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha, J Mol Med. 2010 May; 88(5):523-30.
  • Gleadle, J.M. (2009). F1000Prime Recommendation . Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells, Blood. 2009 May 28; 113(22):5568-74.
  • Gleadle, J.M. (2008). F1000Prime Recommendation . Prolyl 4-hydroxylation regulates Argonaute 2 stability, Nature. 2008 Sep 18; 455(7211):421-4.
  • Kaidonis, G., Gillies, M.C., Abhary, S., Liu, E., Essex, R.W., Chang, J.H., et al. (2016). A single nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients. ACTA DIABETOLOGICA,
    [10.1007/s00592-016-0850-4] [Scopus]
  • Parnham, S., Gleadle, J.M., Leong, D.P.Y., Grover, S.K., bradbrook, C., Woodman, R.J., et al. (2015). Myocardial perfusion is impaired in asymptomatic renal and liver transplant recipients: a cardiovascular magnetic resonance study. Journal of Cardiovascular Magnetic Resonance, 17 pp. 56.
    [Scopus]
  • Parnham, S., Gleadle, J.M., Bangalore, S., Grover, S.K., Perry, R., Woodman, R.J., et al. (2015). Impaired Myocardial Oxygenation Response to Stress in Patients With Chronic Kidney Disease. Journal of the American Heart Association, 4
  • Kaidonis, G., Burdon, K.P., Gillies, M.C., Abhary, S., Essex, R.W., Chang, J.H., et al. (2015). Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema. Ophthalmology, 122(9) pp. 1828-1836.
    [Scopus]
  • Ramiasa, M.N., Cavallaro, A., Mierczynska-Vasilev, A., Christo, S.N., Gleadle, J.M., Hayball, J., et al. (2015). Plasma polymerised polyoxazoline thin films for biomedical applications. Chemical Communications, 51 pp. 4279-4282.
    [Scopus]
  • Hill, K., Gleadle, J., Pulvirenti, M. and McNaughton, D. (2014). The social determinants of health for people with type 1 diabetes that progress to end-stage renal disease. Health Expectations, 18(6) pp. 2513-2521.
    [10.1111/hex.12220] [Scopus] [PubMed]
  • Elkhatim, R., Li, J., Yong, T.Y. and Gleadle, J.M. (2014). Dipping your feet in the water: Podocytes in urine. Expert Review of Molecular Diagnostics, 14(4) pp. 423-437.
    [10.1586/14737159.2014.908122] [Scopus] [PubMed]
  • Bandara, K.V., Michael, M.Z. and Gleadle, J.M. (2014). Hypoxia represses microRNA biogenesis proteins in breast cancer cells. BMC Cancer, 14 pp. Art 533.
    [10.1186/1471-2407-14-533] [Scopus] [PubMed Central] [PubMed]
  • Karttunen, S., Duffield, M., Scrimgeour, N., Squires, L., Lim, W.L., Dallas, M.L., et al. (2014). Oxygen-dependent hydroxylation by Factor Inhibiting HIF (FIH) regulates the TRPV3 ion channel. Journal of Cell Science, 128(2) pp. 225-231.
    [Scopus]
  • Parnham, S., Gleadle, J., De Pasquale, C. and Selvanayagam, J. (2014). Myocardial Ischemia Assessment in Chronic Kidney Disease: Challenges and Pitfalls. Frontiers in Cardiovascular Medicine, 1(13)
  • Li, J., Yong, T., Michael, M. and Gleadle, J.M. (2014). Micrornas: are they the missing link between hypoxia and pre-eclampsia? HYPERTENSION IN PREGNANCY, 33(1) pp. 102-114.
    [10.3109/10641955.2013.832772] [Scopus] [PubMed]
  • Li, J., McNicholas, K., Yong, T., Rao, N., Coates, P., Higgins, G., et al. (2014). BK Virus Encoded MicroRNAs Are Present in Blood of Renal Transplant Recipients With BK Viral Nephropathy. American Journal of Transplantation, 14(5) pp. 1183-1190.
    [10.1111/ajt.12694] [Scopus] [PubMed]
  • Fang, D., King, H., Li, J. and Gleadle, J.M. (2013). Exosomes and the kidney: blaming the messenger. Nephrology, 18(1) pp. 1-10.
    [10.1111/nep.12005] [Scopus] [PubMed]
  • Bennett, P., Miller, M.D., Woodman, R., Hill, K.E., Murray, S.M. and Gleadle, J. (2013). Nutrition screening by nurses in dialysis. Journal of Clinical Nursing, 22(5-6) pp. 723-732.
    [10.1111/j.1365-2702.2012.04286.x] [Scopus]
  • King, H.W., Michael, M.Z. and Gleadle, J. (2012). Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer, 12 pp. 421.
    [10.1186/1471-2407-12-421] [Scopus]
  • Neal, C.S., Michael, M.Z., Pimlott, L.K., Yong, T.Y., Li, J. and Gleadle, J. (2011). Circulating microRNA expression is reduced in chronic kidney disease. Nephrology Dialysis Transplantation, 26(11) pp. 3794-3802.
    [10.1093/ndt/gfr485] [Scopus]
  • Li, J., Yong, T.Y., Michael, M.Z. and Gleadle, J. (2010). The role of microRNAs in kidney disease. Nephrology, 15(6) pp. 599-608.
    [10.1111/j.1440-1797.2010.01363.x] [Scopus] [PubMed]
  • Neal, C.S., Michael, M.Z., Rawlings, L.H., Van der Hoek, M. and Gleadle, J. (2010). The VHL-dependent regulation of microRNAs in renal cancer. BMC Medicine, 21(8) pp. 1-17.
    [10.1186/1741-7015-8-64] [Scopus] [PubMed Central] [PubMed]
  • Brooks, J.T.S., Elvidge, G.P., Glenny, L., Gleadle, J., Liu, C., Ragoussis, J., et al. (2009). Variations within oxygen-regulated gene expression in humans. Journal of Applied Physiology, 106(1) pp. 212-220.
    [10.1152/japplphysiol.90578.2008] [Scopus] [PubMed Central] [PubMed]
  • Gleadle, J. (2009). Review article: How cells sense oxygen: Lessons from and for the kidney. Nephrology, 14(1) pp. 86-93.
    [10.1111/j.1440-1797.2008.01064.x] [Scopus] [PubMed]
  • Camps, C., Buffa, F., Colella, S., Moore, J., Sotiriou, C., Sheldon, H., et al. (2008). hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clinical Cancer Research, 14(5) pp. 1340-1348.
    [10.1158/1078-0432.CCR-07-1755] [Scopus]
  • Gee, H.E., Camps, C., Buffa, F., Colella, S., Sheldon, H., Gleadle, J., et al. (2008). MicroRNA-10b and breast cancer metastasis. Nature, 455(7216) pp. E8-E9.
    [10.1038/nature07362] [Scopus] [PubMed]
  • Pollard, P.J., Loenarz, C., Mole, D.R., McDonough, M.A., Gleadle, J., Schofield, C.J., et al. (2008). Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. Biochemical Journal, 416(3) pp. 387-394.
    [10.1042/BJ20081238] [Scopus] [PubMed]
  • Roberts, I.S. and Gleadle, J. (2008). Familial nephropathy and multiple exostoses with exostosin-1 (EXT1) gene mutation. Journal of The American Society of Nephrology, 19(3) pp. 450-453.
    [10.1681/ASN.2007080842] [Scopus]
  • Elvidge, G.P., Glenny, L., Appelhoff, R.J., Ratcliffe, P.J., Ragoussis, J. and Gleadle, J.M. (2006). Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition - The role of HIF-1 alpha, HIF-2 alpha, and other pathways. Journal of Biological Chemistry, 281(22) pp. 15215-15226.
    [Scopus]
  • Tian, Y.M., Mole, D.R., Ratcliffe, P.J. and Gleadle, J.M. (2006). Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation. Biochemical Journal, pp. 179-186.
    [Scopus]
  • Appelhoff, R.J., Tian, Y.M., Raval, R.R., Turley, H., Harris, A., Pugh, C.W., et al. (2004). Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor. Journal of Biological Chemistry, 279(37) pp. 38458-38465.
    [Scopus]
  • Bishop, T., Lau, K.W., Epstein, A.C.R., Kim, S.K., Jiang, M., O'Rourke, D., et al. (2004). Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans. PLOS BIOLOGY, 2(10) pp. 1549-1560.
    [Scopus]
  • Stolze, I.P., Tian, Y.M., Appelhoff, R.J., Turley, H., Wykoff, C.C., Gleadle, J.M., et al. (2004). Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes. Journal of Biological Chemistry, 279(41) pp. 42719-42725.
    [Scopus]
  • Hewitson, K.S., McNeill, L.A., Riordan, M.V., Tian, Y.M., Bullock, A.N., Welford, R.W., et al. (2002). Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family. Journal of Biological Chemistry, 277 pp. 26351-26355.
    [Scopus]
  • Lavista-Llanos, S., Centanin, L., Irisarri, M., Russo, D.M., Gleadle, J.M., Bocca, S.N., et al. (2002). Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar. Molecular and Cellular Biology, 22(19) pp. 6842-6853.
    [Scopus]
  • McNeill, L.A., Hewitson, K.S., Gleadle, J.M., Horsfall, L.E., Oldham, N.J., Maxwell, P.H., et al. (2002). The use of dioxygen by HIF prolyl hydroxylase (PHD1) Bioorganic & Medicinal Chemistry Letters, 12(12) pp. 1547-1550.
    [Scopus]
  • Epstein, A.C.R., Gleadle, J.M., McNeill, L.A., Hewitson, K.S., O'Rourke, J., Mole, D.R., et al. (2001). C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell, 107(1) pp. 43-54.
    [Scopus]
  • Pugh, C.W., Gleadle, J.M. and Maxwell, P.H. (2001). Hypoxia and oxidative stress in breast cancer hypoxia signalling pathways. BREAST CANCER RESEARCH, 3 pp. 313-317.
  • Scott, P.A.E., Gleadle, J.M., Bicknell, R. and Harris, A. (1998). Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines . International Journal of Cancer, 75 pp. 706-712.
    [Scopus]
  • Maxwell, P.H., Dachs, G.U., Gleadle, J.M., Nicholls, L.G., Harris, A.L., Stratford, I.J., et al. (1997). Hypoxia-Inducible Factor-1 Modulates Gene Expression in Solid Tumors and Influences Both Angiogenesis and Tumor Growth. Proceedings of the National Academy of Sciences of the United States of America, 94(15) pp. 8104-8109.
    [Scopus]
  • Ratcliffe, P.J., Ebert, B.L., Firth, J.D., Gleadle, J.M., Maxwell, P.H., Nagao, M., et al. (1997). Oxygen regulated gene expression: Erythropoietin as a model system. Kidney International, 51(2) pp. 514-526.
    [Scopus]
  • Gleadle, J.M., Ebert, B.L. and Ratcliffe, P.J. (1995). Diphenylene Iodonium Inhibits the Induction of Erythropoietin and Other Mammalian Genes by Hypoxia. European Journal of Biochemistry, 234(1) pp. 92-99.
    [Scopus]
  • Kaidonis, G., Gillies, M.C., Abhary, S., Liu, E., Essex, R.W., Chang, J.H., et al. (2016). A single nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients. ACTA DIABETOLOGICA,
    [10.1007/s00592-016-0850-4] [Scopus]
  • Parnham, S., Gleadle, J.M., Bangalore, S., Grover, S.K., Perry, R., Woodman, R.J., et al. (2015). Impaired Myocardial Oxygenation Response to Stress in Patients With Chronic Kidney Disease. Journal of the American Heart Association, 4
  • Parnham, S., Gleadle, J.M., Leong, D.P.Y., Grover, S.K., bradbrook, C., Woodman, R.J., et al. (2015). Myocardial perfusion is impaired in asymptomatic renal and liver transplant recipients: a cardiovascular magnetic resonance study. Journal of Cardiovascular Magnetic Resonance, 17 pp. 56.
    [Scopus]
  • Kaidonis, G., Burdon, K.P., Gillies, M.C., Abhary, S., Essex, R.W., Chang, J.H., et al. (2015). Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema. Ophthalmology, 122(9) pp. 1828-1836.
    [Scopus]
  • Ramiasa, M.N., Cavallaro, A., Mierczynska-Vasilev, A., Christo, S.N., Gleadle, J.M., Hayball, J., et al. (2015). Plasma polymerised polyoxazoline thin films for biomedical applications. Chemical Communications, 51 pp. 4279-4282.
    [Scopus]
  • Bandara, K.V., Michael, M.Z. and Gleadle, J.M. (2014). Hypoxia represses microRNA biogenesis proteins in breast cancer cells. BMC Cancer, 14 pp. Art 533.
    [10.1186/1471-2407-14-533] [Scopus] [PubMed Central] [PubMed]
  • Elkhatim, R., Li, J., Yong, T.Y. and Gleadle, J.M. (2014). Dipping your feet in the water: Podocytes in urine. Expert Review of Molecular Diagnostics, 14(4) pp. 423-437.
    [10.1586/14737159.2014.908122] [Scopus] [PubMed]
  • Hill, K., Gleadle, J., Pulvirenti, M. and McNaughton, D. (2014). The social determinants of health for people with type 1 diabetes that progress to end-stage renal disease. Health Expectations, 18(6) pp. 2513-2521.
    [10.1111/hex.12220] [Scopus] [PubMed]
  • Karttunen, S., Duffield, M., Scrimgeour, N., Squires, L., Lim, W.L., Dallas, M.L., et al. (2014). Oxygen-dependent hydroxylation by Factor Inhibiting HIF (FIH) regulates the TRPV3 ion channel. Journal of Cell Science, 128(2) pp. 225-231.
    [Scopus]
  • Li, J., Yong, T., Michael, M. and Gleadle, J.M. (2014). Micrornas: are they the missing link between hypoxia and pre-eclampsia? HYPERTENSION IN PREGNANCY, 33(1) pp. 102-114.
    [10.3109/10641955.2013.832772] [Scopus] [PubMed]

Expertise for media contact

Subject Titles

  • Cancer
  • Kidney disease

Interests

  • Responses to hypoxia

Contact

Add to address book
Phone: +61 8 82046681
Email:
Location: Flinders Medical Centre (6A:148)
Postal address: GPO Box 2100, Adelaide 5001, South Australia

Further information

renal@flinders.edu.au

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