Prof Nick Fazzalari

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Postal address: GPO Box 2100, Adelaide 5001, South Australia

Research and supervision

Publications

Book chapters
  • Fazzalari, N., Costi, J.J. and Hearn, T.C. (2003). Structure and function of normal, degenerate, and surgically fixed spinal segments. In Kai-Uwe Lewandrowski, ed. Advances in Spinal Fusion. New York, USA: Marcel Dekker, pp. 135-154.
Refereed journal articles
  • Fazzalari, N., Martin, B., Reynolds, K., Cleek, T., Badiei, A. and Bottema, M. (2012). A model for the change of cancellous bone volume and structure over time. Mathematical Biosciences, 240(2) pp. 132-140. [10.1016/j.mbs.2012.06.006]
  • Briggs, A., Perilli, E., Parkinson, I., Kantor, S., Wrigley, T., Fazzalari, N., et al. (2012). Measurement of subregional vertebral bone mineral density in vitro using lateral projection dual-energy X-ray absorptiometry: validation with peripheral quantitative computed tomography. Journal of Bone and Mineral Metabolism, 30(2) pp. 222-231. [10.1007/s00774-011-0307-3]
  • Zoehrer, R., Perilli, E., Kuliwaba, J., Shapter, J., Fazzalari, N. and Voelcker, N. (2012). Human bone material characterization: integrated imaging surface investigation of male fragility fractures. Osteoporosis International, 23(4) pp. 1297-1309. [10.1007/s00198-011-1688-9]
  • Mohan, G., Perilli, E., Kuliwaba, J., Humphries, J., Parkinson, I. and Fazzalari, N. (2011). Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. Arthritis Research and Therapy, 13(6) pp. R210. [10.1186/ar3543]
  • Perilli, E., Le, V., Ma, B., Salmon, P., Reynolds, K.J. and Fazzalari, N. (2010). Detecting early bone changes using in vivo micro-CT in ovariectomized, zolendronic acid-treated, and sham-operated rats. Osteoporosis International, 21(8) pp. 1371-1382. [doi:10.1007/s00198-009-1082-z]
  • Kumarasinghe, D., Perilli, E., Tsangari, H., Truong, L., Kuliwaba, J., Hopwood, B., et al. (2010). Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis. Osteoarthritis and Cartilage, 18(10) pp. 1337-1344. [10.1016/j.joca.2010.07.005]
  • Briggs, A., Perilli, E., Parkinson, I., Wrigley, T., Fazzalari, N., Kantor, S., et al. (2010). Novel assessment of subregional bone mineral density using DXA and pQCT and subregional microarchitecture using micro-CT in whole human vertebrae: applications, methods, and correspondence between technologies. Journal of Clinical Densitometry, 13(2) pp. 161-174. [doi:10.1016/j.jocd.2010.01.120]
  • Verrall, G.M., Henry, L., Fazzalari, N., Slavotinek, J.P. and Oakeshott, R.D. (2008). Bone Biopsy of the Parasymphyseal Pubic Bone Region in Athletes With Chronic Groin Injury Demonstrates New Woven Bone Formation Consistent With a Diagnosis of Pubic Bone Stress Injury. American Journal of Sports Medicine, 36(12) pp. 2425-2431. [DOI:10.1177/0363546508324690]
  • Norman, J.A., Shapter, J.G., Short, K., Smith, L.J. and Fazzalari, N. (2008). Micromechanical properties of human trabecular bone: A hierarchical investigation using nanoindentation. Journal of Biomedical Materials Research Part A, 87A(1) pp. 196-202. [doi:10.1002/jbm.a.31766]

Show all publications

Book chapters
  • Fazzalari, N., Costi, J.J. and Hearn, T.C. (2003). Structure and function of normal, degenerate, and surgically fixed spinal segments. In Kai-Uwe Lewandrowski, ed. Advances in Spinal Fusion. New York, USA: Marcel Dekker, pp. 135-154.
Refereed journal articles
  • Fazzalari, N., Martin, B., Reynolds, K., Cleek, T., Badiei, A. and Bottema, M. (2012). A model for the change of cancellous bone volume and structure over time. Mathematical Biosciences, 240(2) pp. 132-140. [10.1016/j.mbs.2012.06.006]
  • Zoehrer, R., Perilli, E., Kuliwaba, J., Shapter, J., Fazzalari, N. and Voelcker, N. (2012). Human bone material characterization: integrated imaging surface investigation of male fragility fractures. Osteoporosis International, 23(4) pp. 1297-1309. [10.1007/s00198-011-1688-9]
  • Briggs, A., Perilli, E., Parkinson, I., Kantor, S., Wrigley, T., Fazzalari, N., et al. (2012). Measurement of subregional vertebral bone mineral density in vitro using lateral projection dual-energy X-ray absorptiometry: validation with peripheral quantitative computed tomography. Journal of Bone and Mineral Metabolism, 30(2) pp. 222-231. [10.1007/s00774-011-0307-3]
  • Mohan, G., Perilli, E., Kuliwaba, J., Humphries, J., Parkinson, I. and Fazzalari, N. (2011). Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. Arthritis Research and Therapy, 13(6) pp. R210. [10.1186/ar3543]
  • Briggs, A., Perilli, E., Parkinson, I., Wrigley, T., Fazzalari, N., Kantor, S., et al. (2010). Novel assessment of subregional bone mineral density using DXA and pQCT and subregional microarchitecture using micro-CT in whole human vertebrae: applications, methods, and correspondence between technologies. Journal of Clinical Densitometry, 13(2) pp. 161-174. [doi:10.1016/j.jocd.2010.01.120]
  • Kumarasinghe, D., Perilli, E., Tsangari, H., Truong, L., Kuliwaba, J., Hopwood, B., et al. (2010). Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis. Osteoarthritis and Cartilage, 18(10) pp. 1337-1344. [10.1016/j.joca.2010.07.005]
  • Perilli, E., Le, V., Ma, B., Salmon, P., Reynolds, K.J. and Fazzalari, N. (2010). Detecting early bone changes using in vivo micro-CT in ovariectomized, zolendronic acid-treated, and sham-operated rats. Osteoporosis International, 21(8) pp. 1371-1382. [doi:10.1007/s00198-009-1082-z]
  • Verrall, G.M., Henry, L., Fazzalari, N., Slavotinek, J.P. and Oakeshott, R.D. (2008). Bone Biopsy of the Parasymphyseal Pubic Bone Region in Athletes With Chronic Groin Injury Demonstrates New Woven Bone Formation Consistent With a Diagnosis of Pubic Bone Stress Injury. American Journal of Sports Medicine, 36(12) pp. 2425-2431. [DOI:10.1177/0363546508324690]
  • Norman, J.A., Shapter, J.G., Short, K., Smith, L.J. and Fazzalari, N. (2008). Micromechanical properties of human trabecular bone: A hierarchical investigation using nanoindentation. Journal of Biomedical Materials Research Part A, 87A(1) pp. 196-202. [doi:10.1002/jbm.a.31766]
  • Smith, L.J., Byers, S., Costi, J.J. and Fazzalari, N. (2008). Elastic fibers enhance the mechanical integrity of the human lumbar annulus fibrosus in the radial direction. Annals of Biomedical Engineering, 36(2) pp. 214-223. [doi:10.1007/s10439-007-9421-8]
  • Kurmis, A.P., Barber, C., Slavotinek, J.P. and Fazzalari, N. (2007). A Mn[Cl.sub.2]-based MR signal intensity linear response phantom. Radiologic Technology, 79(2) pp. 119-125. [Link]
  • Badiei, A., Bottema, M.J. and Fazzalari, N.L. (2007). Influence of Orthogonal Overload on Human Vertebral Trabecular Bone Mechanical Properties. Journal of Bone and Mineral Research, 22(11) pp. 1690-1699. [Link]
  • Badiei, A., Bottema, M.J. and Fazzalari, N. (2006). Expected and Observed Changes to Descriptors of Trabecular Architecture with Aging - A Comparison of Measurement Techniques. Australasian Physical and Engineering Sciences in Medicine, 29(1) pp. 48-52.
  • Fazzalari, N., Parkinson, I.H., Fogg, Q.A. and Sutton-Smith, P. (2006). Antero-postero differences in cortical thickness and cortical porosity of T12 to L5 vertebral bodies. Joint Bone Spine, 73(3) pp. 293-297. [doi:10.1016/j.jbspin.2005.03.023]
  • Costi, J.J., Hearn, T.C. and Fazzalari, N. (2002). The effect of hydration on the stiffness of intervertebral discs in an ovine model. Clinical Biomechanics, 17(6) pp. 446-455. [doi:10.1016/S0268-0033(02)00035-9]
  • Fazzalari, N., Costi, J.J., Hearn, T.C., Fraser, R., Vernon-Roberts, B., Hutchinson, J., et al. (2001). Mechanical and pathologic consequences of induced concentric anular tears in an ovine model. Spine, 26(23) pp. 2575-2581.
Refereed conference papers
  • Cleek, T.M., Bottema, M.J., Fazzalari, N. and Reynolds, K.J. (2005). Assessment of Fourier Tools for Cancellous Bone Structure Analysis. In Brian C. Lovell; Anthony J. Maeder, ed. APRS Workshop Proceedings, WDIC 2005. St Lucia, Queensland: University of Queensland Press. APRS Workshop on Digital Image Computing. Griffith University, Brisbane. Feb 2005.
  • Badiei, A., Bottema, M.J. and Fazzalari, N. (2005). Expected and observed changes to architectural parameters of trabecular bone with aging - A comparison of measurement techniques. In BC Lovell, AJ Maeder, T Caelli, S Oursellin, ed. Digital Image Computing Techniques and Applications (DICTA) 2005. Danvers, USA: IEEE Computer Society Conference Publishing Service. Digital Image Computing Techniques and Applications (DICTA) 5. Cairns, Queensland, Australia. Dec 2005, pp. 491-497.
Conference publications
  • Costi, J.J., Stanley, R.M., Tettis, H. and Fazzalari, N. (2008). Human versus sheep intervertebral disc mechanical and vertebral cortical bone strain properties. In Proceedings of the 14th Annual Meeting of the Australian and New Zealand Orthopaedic Research Society (ANZORS) 14th Annual Meeting of the Australian and New Zealand Orthopaedic Research Society (ANZORS)
  • Costi, J.J., Stanley, R.M., Smith, L.J., Tettis, H., Tsangari, H., Hearn, T.C., et al. (2008). The effects of lumbar motion segment degeneration on strain magnitudes at the vertebral cortices during compression, bending and torsion. In Proceedings of the 14th Annual Meeting of the Australian and New Zealand Orthopaedic Research Society (ANZORS) 14th Annual Meeting of the Australian and New Zealand Orthopaedic Research Society (ANZORS)
  • Costi, J.J., Stanley, R.M., Smith, L.J., Tettis, H., Tsangari, H., Hearn, T.C., et al. (2008). The effect of intervertebral disc degeneration on vertebral cortical strains and disc mechanical properties. In Transactions of the 54th Annual Meeting of the Orthopaedic Research Society. Rosemont, IL, USA: Orthopaedic Research Society. 54th Annual Meeting of the Orthopaedic Research Society. San Francisco, CA, USA. Mar 2008, pp. 1439-1439.
  • Costi, J.J., Stanley, R.M., Smith, L.J., Tettis, H., Tsangari, H., Hearn, T.C., et al. (2008). The effect of intervertebral disc degeneration on vertebral cortical strains and disc mechanical properties. In Proceedings of the 35th Annual Meeting of the International Society for Study of the Lumbar Spine (ISSLS) 35th Annual Meeting of the International Society for Study of the Lumbar Spine (ISSLS)
  • Costi, J.J., Stanley, R.M., Smith, L.J., Tettis, H., Tsangari, H., Hearn, T.C., et al. (2008). The effect of intervertebral disc degeneration on vertebral cortical strains and disc mechanical properties. In Proceedings of the 19th Annual Scientific Meeting of the Spine Society of Australia. 19th Annual Scientific Meeting of the Spine Society of Australia.
  • Smith, L.J., Byers, S., Costi, J.J. and Fazzalari, N. (2007). Elastic fibres enhance the mechanical integrity of the human lumbar anulus fibrosus transverse to the collagen fibre direction. In Proceedings of the Australian and New Zealand Orthopaedic Research Society: 13th Annual Scientific Meeting. ANZORS. Australian and New Zealand Orthopaedic Research Society: 13th Annual Scientific Meeting. Auckland, New Zealand. Oct 2007, pp. 36-36.
  • Reynolds, K.J., Cleek, T.M., Burrow, L.M. and Fazzalari, N. (2006). Three-dimensional stimulation of trabecular bone remodelling. In Abstracts of the 2006 IOF + ANZBMS Combined Meeting. 3rd IOF Asia-Pacific Regional Conference on Osteoporosis and 16th Annual Meeting of the Australian & New Zealand Bone & Mineral Society. Port Douglas, QLD. Oct 2006. [Link]
  • Tettis, H., Costi, J.J., Stanley, R.M., Fazzalari, N. and Hearn, T.C. (2005). A TOOL FOR DYNAMIC PRESSURE DISTRIBUTION ANALYSIS IN EXPLANTED TISSUES: A PILOT STUDY. In Proceedings of the 16th Annual Scientific Meeting of the Spine Society of Australia. 16th Annual Scientific Meeting of the Spine Society of Australia.
  • Costi, J.J., Tettis, H., Stanley, R.M., Hearn, T.C. and Fazzalari, N. (2005). Validation of a method and tool for measuring in-vitro spine segment stiffness, cortical strain and pressure distribution in a hydrated, uniform loading environment: A pilot study. In Proceedings of the 15th Annual Meeting of the European Orthopaedic Research Society (EORS) 15th European Orthopaedic Research Society (EORS) Lisbon, Portugal.
  • Costi, J.J., Tettis, H., Stanley, R.M., Hearn, T.C. and Fazzalari, N. (2005). VALIDATION OF A METHOD TO MEASURE IN-VITRO SPINE SEGMENT STIFFNESS, CORTICAL STRAIN AND PRESSURE DISTRIBUTION IN A HYDRATED, UNIFORM LOADING ENVIRONMENT. In Proceedings of the 16th Annual Scientific Meeting of the Spine Society of Australia. 16th Annual Scientific Meeting of the Spine Society of Australia.
  • Costi, J.J., Tettis, H., Stanley, R.M., Hearn, T.C. and Fazzalari, N. (2005). IN-VITRO MEASUREMENT OF SPINE SEGMENT STIFFNESS, CORTICAL STRAIN AND PRESSURE DISTRIBUTION IN A HYDRATED, UNIFORM LOADING ENVIRONMENT: A PILOT STUDY ' PART 1 EFFECT OF SEQUENTIAL VERTEBRAL BONE REMOVAL. In Proceedings of the 16th Annual Scientific Meeting of the Spine Society of Australia. 16th Annual Scientific Meeting of the Spine Society of Australia.
  • Costi, J.J., Tettis, H., Stanley, R.M., Hearn, T.C. and Fazzalari, N. (2005). IN-VITRO MEASUREMENT OF SPINE SEGMENT STIFFNESS AND PRESSURE DISTRIBUTION IN A HYDRATED, UNIFORM LOADING ENVIRONMENT: A PILOT STUDY ' PART 2 EFFECT OF ANNULAR DISC INJURY. In Proceedings of the 16th Annual Scientific Meeting of the Spine Society of Australia. 16th Annual Scientific Meeting of the Spine Society of Australia.
  • Burrow, L.M., Reynolds, K.J., Cleek, T.M. and Fazzalari, N. (2005). Three-dimensional simulation of trabecular bone remodelling. In Conference Handbook: Engineering & Physical Sciences in Medicine (EPSM) & Australian Biomedical Engineering Conference (ABEC) 2005. Engineering & Physical Sciences in Medicine (EPSM) & Australian Biomedical Engineering Conference (ABEC) 2005. Adelaide. Oct 2005, pp. 272.
  • Costi, J.J., Hearn, T.C. and Fazzalari, N. (2001). Biomechanical studies of the disco-vertibral joint in an ovine model of disc degeneration. In Proceedings of the 13th Trigennial Congress of the Asian Pacific Orthopaedics Association. 13th Trigennial Congress of the Asian Pacific Orthopaedics. Adelaide, SA. Jan 2001.

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