Year
2012
Units
4.5
Contact
4 x 1-hour tutorials per semester
1 x 1-hour workshop weekly
4 x 3-hour practicals per semester
2 x 1-hour on-line lectures weekly
Prerequisites
1 1 of BIOL1102, BIOL1203
2 1 of CHEM1201, CHEM1101, CHEM1010
Must Satisfy: (1 and 2)
Topic description
In this topic, students will learn the principles and the regulation of: DNA structure, replication, damage and repair; gene transcription and translation; and protein synthesis, structure, folding and function. Students will gain an overview of the subject matter, will work in teams to apply their knowledge to solve problems in genetic engineering and will discover the relationship between DNA structure and function and develop skills in DNA manipulation, experimental design and scientific report writing.
Educational aims
The overall aim of this topic is to develop students' knowledge and understanding of the structure and function of DNA, RNA and proteins and to provide them with opportunities to apply their knowledge and understanding to the solution of 'real-world' problems related to genetic engineering.
Expected learning outcomes
At the completion of the topic, students are expected to be able to:

  1. Explain clearly in both oral and written form the processes and regulation of: DNA structure, replication and repair; gene transcription and translation; protein structure, synthesis, folding and function
  2. Apply their knowledge to the practice of genetic engineering
  3. Work competently in a molecular biology laboratory and produce reliable and reproducible data
  4. Understand the likely artefacts inherent in working with biological materials and be cognisant of the use of controls to mitigate against artefactual results
  5. Maintain a laboratory notebook such that others can reproduce their work
  6. Present experimental results in tables and graphs in a format suitable for publication in a scientific journal
  7. Interpret experimental data in the context of current knowledge in the field of molecular biology
  8. Collaborate effectively with colleagues to solve problems
  9. Perform routine calculations required for the preparation of laboratory reagents