Dr Craig Wallington-Beddoe

Senior Research Fellow

College of Medicine and Public Health

Research expertise

I undertake basic and translational research in the blood cancer multiple myeloma focusing on biomarker development and novel therapeutic strategies.

Research expertise

I undertake basic and translational research in the blood cancer multiple myeloma focusing on biomarker development and novel therapeutic strategies.

place Health Sciences Building
GPO Box 2100, Adelaide 5001, South Australia

Dr Wallington-Beddoe is a Consultant Clinical Haematologist at Flinders Medical Centre and Senior Research Fellow at Flinders University. He is Director of Haematology Clinical Trials for Southern Adelaide Local Health Network where he is the Principal Investigator for several clinical trials for patients with the aggressive blood cancer multiple myeloma. Being a cancer biologist and clinical haematologist, Dr Wallington-Beddoe seeks to translate research findings to the clinic, focusing on novel biomarkers and therapeutic strategies for multiple myeloma.

After completing specialist medical qualifications (FRACP/FRCPA) in the discipline of haematology at Westmead Hospital in Sydney, Dr Wallington-Beddoe undertook PhD studies at The University of Sydney. His work sought to investigate novel therapeutic strategies for acute lymphoblastic leukaemia and resulted in several high impact publications and numerous national and international conference presentations. In recognition of this work, Dr Wallington-Beddoe was awarded the 2012 Haematology Society of Australia and New Zealand Albert Baikie Memorial Medal and New Investigator Grant. Supported by a NHMRC Peter Doherty Post-Doctoral Research Fellowship, he relocated to Adelaide in 2013 to undertake post-doctoral research at the Centre for Cancer Biology, University of South Australia. This period of research elucidated how certain sphingolipid enzymes can be targeted in multiple myeloma to enhance responses to proteasome inhibitors, an important class of drugs for this cancer, resulting in several key publications.

Dr Wallington-Beddoe now heads the Flinders University division of an integrated translational multiple myeloma research program in tandem with the Centre for Cancer Biology, University of South Australia, which aims to maximise clinical and research outcomes for this blood cancer.

Qualifications

BSc (Hons), MBBS (Hons), MBiostat, PhD, FRACP, FRCPA

Honours, awards and grants

Leukaemia Foundation of Australia PhD (clinical) Scholarship (2010 – 2012)

NHMRC Medical/Dental PhD Scholarship (2010 – 2012)

Cancer Institute New South Wales Research Scholar Award (2010 – 2012)

The Royal College of Pathologists of Australasia Research Award (2010 – 2011)

Haematology Society of Australia and New Zealand Educational Grant (2011)

Haematology Society of Australia and New Zealand New Investigator Scholarship (2013)

Albert Baikie Memorial Medal, Haematology Society of Australia and New Zealand (2012)

Royal Adelaide Hospital Mary Overton Early Career Fellowship (2014-2016)

NHMRC Peter Doherty Biomedical Early Career Fellowship (2014-2017)

Royal Australian College of Physicians Research Establishment Fellowship (2018)

Viertel Foundation Clinical Investigator Award (2019)

NHMRC Project Grant (2019 - 2021)

Flinders Health and Medical Research Institute Kickstart Grant (2019)

Royal Australian College of Physicians Research Establishment Fellowship (2020)

Key responsibilities

Clinical Haematologist, Flinders Medical Centre

Director of Haematology Clinical Trials, Flinders Medical Centre

Multiple Myeloma Translational Research Laboratory Leader, Flinders University

Research expertise
Biochemistry and cell biology
Oncology and carcinogenesis
Research interests

Haematological malignancies with a particular focus on multiple myeloma. My research seeks to manipulate endoplasmic reticulum stress in myeloma cells to enhance the cytotoxic effects of proteasome inhibitors and other novel agents, particularly in the setting of relapsed or refractory disease. More recently, I am investigating the role of adhesion proteins on myeloma cells with the aim of therapeutically targeting both the bone marrow microenvironment and the malignant cell itself.

Teaching interests

Cell biology, haematology and blood cancers.

Supervisory interests
Cancer biology
Multiple myeloma
Higher degree by research supervision
Current
Principal supervisor: Multiple myeloma (1)
Associate supervisor: Multiple myeloma (1)
Completion
Associate supervisor: Multiple myeloma (1)
Publications
Expert for media contact
Cancer
Haematology
Multiple myeloma
Available for contact via
Or contact the media team
+61 8 82012092
0427 398 713
Researcher
Media expert
Media expertise
  • Cancer
  • Haematology
Interests
  • Multiple myeloma

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