Negative pressure

Biomedical Research Support

Lower body negative pressure chamber for MRI

FBE, Flinders Biomedical Engineering, have developed a lower body negative pressure (LBNP) chamber specifically for use in an MRI. It will be used to monitor cardiac effectiveness by simulating the process of standing upright. Negative pressure, or external  decompression, is applied to the lower body using a vacuum of 30 millimeters of mercury. LBNP can be used to study orthostatic  intolerance (e.g. fainting when standing),  to assess cardiovascular  function and to simulate severe hemorrhage.

Description of devices developed by BME

Negative pressure tank, lower body, for MRI

A new negative pressure chamber was remade for use in an MRI. This required building a curved chamber that would fit the opening of the MRI with no magnetic metal components.

Special features include polycarbonate struts, nylon screws, simple pressure release levers, raisable footpads. Device is intended for use on human subjects under strict medical supervision. [BME1544] 

Negative pressure tank, lower body

Enclosure for studying baro-receptors in lower limbs. Polycarbonate tank with waist sealing yoke depressurises lower body to 50 mmHg. Safety pressure release switches in easy reach of subject. Device is intended for use on human subjects under strict medical supervision. [BME1488]

Negative pressure cabinet for MRI

Negative pressure cabinet struts

Gauges for lower body negative pressure

Negative pressure tank

 

 

Publications using BME developed devices