Professor Arduino Mangoni

Strategic Professor and Head of Clinical Pharmacology

College of Medicine and Public Health

place Flinders Medical Centre (6D:302)
GPO Box 2100, Adelaide 5001, South Australia
Arduino trained in Clinical Pharmacology, Cardiology and Internal Medicine in Milan, Boston and London. In 2003 he was awarded a PhD at King's College London and was appointed as Senior Lecturer in the Department of Clinical Pharmacology at Flinders University. He was promoted to Associate Professor in 2007 before taking up the Chair of Medicine of Old Age at the University of Aberdeen in 2010. In 2013 he returned to Flinders University as Professor of Clinical Pharmacology and Senior Consultant in Clinical Pharmacology and Internal Medicine. 
Qualifications

MD(Hons), University of Milan, 1991

Specialist Diploma in Cardiology and Internal Medicine, University of Milan (Italy), 1995

Certificate of Completion of Specialist Training in Clinical Pharmacology & Therapeutics, Specialist Training Authority, London (UK), 2003

Certificate of Completion of Specialist Training in General (Internal) Medicine, Specialist Training Authority, London (UK), 2003

PhD, King's College London (UK), 2003

MRCP(UK), 2003

FRACP (General Medicine), 2005

FRCP (London), 2009

FRCP (Glasgow), 2010

FRCP (Edinburgh), 2011

FRACP (Clinical Pharmacology), 2013

Honours, awards and grants

Carrick citation for outstanding contributions to student learning "For promotion of safe and effective medication management through an innovative e-learning pharmacology course for Nurse Practitioners in urban, rural and remote areas of Australia". (2007)

Visiting Professor, University of Sassari, Italy (2012, 2014, 2015, 2016, 2018, 2019)

Honorarprofessor, Institut für Pharmakologie und Toxikologie, Technische Universität Dresden, Germany (2019)

Fellow of the British Pharmacological Society (2012).

Grants:

2015: AA Mangoni, A Rowland, J Miners, T Chataway, M Michael, MG Burt, D Keating, L Thurgood, M Sorich. Establishment of the Flinders Metabolomic Research facility. Flinders Faculty of Health Sciences, AUD 20,000

2015: MG Burt, AA Mangoni, L Heilbronn. Determination of the effect of relative hyperglycaemia on markers of cardiovascular risk. Flinders Faculty of Health Sciences Small Grants, AUD 19,000

2017: Mangoni AA, Woodman RJ, Shanahan EM, Wiese MD. Effects of methotrexate on blood pressure and arterial function in rheumatoid arthritis. Investigator initiated trial research grant. medac Gesellschaft für klinische Spezialpräparate mbH (Germany), 4 years, AUD 550,000

2019: Pintus GF, Mangoni AA, Zinellu A, Fois A. Investigating predictive biomarkers and cellular/molecular determinants of chronic respiratory diseases. Qatar University Collaborative Grants, 2 years, AUD 315,575

2019: Mangoni AA. Dimethylarginine dimethylaminohydrolase 1: a new target for triple negative breast cancer. Tour de Cure, Senior Research Grants, 1 year, AUD 198,332

Research expertise
Cardiovascular medicine and haematology
Clinical sciences
Pharmacology and pharmaceutical sciences
Research interests
  •   Chemistry of dimethylarginine dimethylaminohydrolase 1 (DDAH1)
  •   Effect of DDAH1 inhibition in experimental models of cancer and fibrosis
  •   Arginine metabolomics and age-associated disease states
  •   Pharmacoepidemiology and drug safety in old age
  •   Identification and assessment of patient-centred outcomes in old age
  •   Autoimmune disease states as a model of premature vascular ageing and atherosclerosis
  •   Repurposing of anti-inflammatory drugs for cardiovascular risk management
Topic coordinator
MMED8203 Knowledge of Health and Illness 2
Supervisory interests
Cardiovascular and internal medicine
Clinical biochemistry
Clinical pharmacology
Hypertension/cardiology
Pharmacological interventions on cardiovascular function
Structure/function of vascular beds
Higher degree by research supervision
Completion
Principal supervisor: Pharmacology (2), Design of novel DDAH inhibitors (Univ of Aberdeen) (1), Methotrexate and markers of cardiovascular risk in rheumatoid arthritis (Univ of Aberdeen) (1)
Associate supervisor: Pharmacology (3)
Higher degree by research student achievements
Leena Baghdadi

Best research manuscript - MAY 2017

Leena Baghdadi

Best PhD Thesis - APR 2018

Publications

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