Professor Jonathan Gleadle

Professor of Medicine

College of Medicine and Public Health

place Flinders Medical Centre (6A:148)
GPO Box 2100, Adelaide 5001, South Australia
Jonathan Gleadle is a Consultant Nephrologist at Flinders Medical Centre and Professor of Medicine at Flinders University and is continuing to pursue his activities in clinical medicine, teaching and research.  For the preceeding five years he was the University Lecturer in Nephrology and General Medicine at Oxford University.  He is currently heading an independent Research Group at Flinders focusing on the regulation of gene expression and microRNAs by oxygen and its implications for renal disease and renal cancer.  His research interests have focussed on the sensing of oxygen by cells; a topic with broad relevance to the understanding of cellular physiology, ischaemic disease and cancer.
Qualifications
BM BCh, MA (Oxon), DPhil (Oxon), FRCP(UK), FRACP
Research expertise
Biochemistry and cell biology
Clinical sciences
Molecular biology
Research interests

Research over the last five years has focussed on the clinical relevance of microRNAs in renal disease and renal cancer and on molecular and cellular responses to oxygen. The sensing of oxygen by cells has broad relevance to the understanding of cellular physiology, renal failure, ischaemic disease and cancer. Recent clinical studies have also examined the clinical relevance of microRNAs to renal disease and viruses, the role of Cardiac MRI in renal patients, renal dysfunction following cardiac surgery and the use of novel surfaces to facilitate novel urine diagnostics and anti-infective strategies.

Teaching interests
Renal Medicine
History and Examination
Author of 'History and Examination at a Glance'
Author renal chapters 'Medicine at a Glance'
Author ' Preparation for the FRACP; Questions and Answers'
Supervisory interests
Exosomes
Hypoxia
MicroRNA
Oxygen
Oxygen-sensing
Renal failure
Renal transplantation
Responses to hypoxia
Higher degree by research supervision
Current
Principal supervisor: Renal failure following cardiac surgery (1)
Associate supervisor: Diabetes and Renal Failure (1)
Completion
Principal supervisor: Hypoxia and MicroRNAs (1)
Associate supervisor: Cardiac MRI and renal disease (1)
Publications
Expert for media contact
Cancer
Kidney disease
Responses to hypoxia
Available for contact via
Or contact the media team
+61 8 82012092
0427 398 713
Media expertise
  • Cancer
  • Kidney disease
Interests
  • Responses to hypoxia
Further information

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