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  • Flinders Health and Medical Research Institute

    About

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Brain Organoid Therapeutics (bot)

FHMRI Platforms Facilities Brain Organoid Therapeutics

Brain Organoid Therapeutics (BOT) is a screening platform that leverages innovative human neural models in vitro to evaluate the efficacy and neurotoxicity of agents and therapeutics interacting with the nervous system. 

Our expert team employs rigorous, state-of-the-art research methods to develop electrophysiologically-relevant neural models that closely mimic the human nervous system. Focused on scientific excellence and patient well-being, we collaborate with industry and academic researchers to provide our services and accelerate the translation of therapeutic breakthroughs while minimising neurotoxicity risks.

BOT operates under Flinders University and is located at the South Australia Health and Medical Research Centre (SAHMRI).

Specialised services 

Equipment 

Contact us 

BOT website

Specialised services

Preclinical modeling and screening 

  • Drug screening
  • Induced pluripotent stem cells (iPSCs)
  • 2D and 3D models in vitro
  • Disease models

Functional characterisation and imaging

  • Electrophysiology
  • Neuronal phenotyping
  • High content imaging

Computational Analysis

  • Machine learning and bioinformatics analysis

Clinical Development

  • Clinical trial support 

Equipment

Automation & Liquid Handling

  • Janus Automated Liquid Handler
  • Assist Plus Pipetting Robot
  • 3D Bioprinters

Electrophysiology Suite 

  • Whole-Cell Patch Clamping
  • Multi-Electrode Arrays
  • Calcium Imaging 

Advanced Imaging & Metabolic Profiling

  • High Content Confocal Microscopes
  • Incucyte Live Cell Imaging System
  • Seahorse Real Time Cell Metabolism Analyzer

Computational Infrastructure 

  • Dedicated server (>400TB)
  • High performance computing systems (HPCs)

Get in contact with us

If you would like more information, have a potential project, or are interested in partnering with us, please contact:

brainorganoid@flinders.edu.au

Prof. Cedric Bardy

Visit us

SAHMRI Biomed City

North Terrace, Adelaide SA 5000, Australia

Learn more

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Sturt Rd, Bedford Park
South Australia 5042

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Last Updated: 13 May 2025

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