Dr Claire Jessup

Senior Lecturer

College of Medicine and Public Health

place Flinders Medical Centre (6E:118)
GPO Box 2100, Adelaide 5001, South Australia

Claire's research examines intracellular communication within pancreatic islets. Her work is focussed on a new potential cure for Type 1 diabetes - pancreatic islet transplantation. Recent work from this group has demonstrated the potential of a cellular cotherapy (endothelial progenitor cells) in improving islet transplantation outcomes. The Islet Biology Lab uses cellular and molecular techniques, diabetes and transplantation models, and confocal microscopy to probe the intricate interactions between insulin-producing beta cells and other cell types within the pancreatic islet.

Qualifications
BBiotech(Hons); PhD
Honours, awards and grants

NHMRC Project "Desmoglein-2; a novel lifeline to treat diabetes" CID, 2016-2018

Highest Impact Paper of the Year, Centre for Neuroscience, 2013

Vice Chancellor's Award for Early Career Researchers, 2012

SA Young Tall Poppy Science Award, 2011


Research expertise
Biochemistry and cell biology
Immunology
Medical physiology
Ophthalmology and optometry
Research interests

My primary research interests focus on the vasculature of the pancreatic islet, and the relevance of cell signalling to diabetes. The dense network of capillaries is crucial for the sensitive detection of blood glucose and release of insulin. Many islets die when they are disconnected from their blood supply for transplantation purposes - limiting the success of islet transplantation. In collaboration with Dr Claudine Bonder in the Centre for Cancer Biology we are investigating the use of endothelial progenitor cells to swiftly reconnect the blood supply to transplanted islets and improve their function and survival. Visit my lab page for more!

As an Adjunct Senior Lecturer with the University of Adelaide, I work collaboratively with the Islet Transplantation and Dendritic Cell Biology Laboratory run by Prof Toby Coates.

Topic coordinator
MMED9150 Human Homeostasis (MD)
Topic lecturer
MMED3203 Knowledge of Health and Illness 2
MMED3932 Body Systems
MMED3941 Human Musculoskeletal Anatomy
Supervisory interests
Beta cells
Cell signalling
Corneal transplantation
Diabetes
Endothelial function
Immune mechanisms
Immunology
Insulin secretion
Islet transplantation
Structure/function of vascular beds
Vascular
Higher degree by research supervision
Current
Associate supervisor: GUT, ENDOCRINE CELLS, SEROTONIN (1), ENDOTHELIAL CELLS, DENGUE VIRUS (1), DIABETES, ZINC TRANSPORTERS, PANCREATIC BETA CELLS (1)
Completion
Associate supervisor: Dendritic cells, transplantation rejection and pancreatic islets (Univ Adelaide) (1), Gene therapy, pancreatic islet transplantation and diabetes (Univ. Adelaide) (1)
Higher degree by research student achievements
Ms Darling Rojas

Thomas E. Starzl Postdoctoral Fellowship in Transplantation Biology - NOV 2011

Ms Amy Hughes

PhD Dean's Commendation - APR 2013

Publications
Expert for media contact
Cardiovascular system
Diabetes
Available for contact via
Or contact the media team
+61 8 82012092
0427 398 713
Media expertise
  • Cardiovascular system
  • Diabetes
Further information

Find our latest lab publication here

Congrats Shane Grey and team on a fantastic new funding announcement

Congratulations to our collaborator and friend Claudine Bonder!

Making medical history in Adelaide

My lab is part of the Flinders Centre for Neuroscience

SOME COOL LINKS: https://www.facebook.com/kidneydiabetesresearch/, https://www.facebook.com/centreforneuroscience/, IPITA Young Investigator Committee

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