Dr Claire Jessup

Senior Lecturer

College of Medicine and Public Health

place Flinders Medical Centre (6E:118)
GPO Box 2100, Adelaide 5001, South Australia

Dr Claire Jessup is a medical researcher interested in harnessing the power of the immune system to modulate disease. Specific research projects examine the molecular activation of immune cells involved in the rejection of transplants and the development of autoimmune diseases (e.g. Type 1 diabetes).

Dr Jessup heads the iMOD and Islet Biology group within the College of Medicine and Public Health. Her laboratory utilises techniques including flow cytometry, gene therapy, pancreatic islet isolation, in vitro beta cell and immune assays, confocal microscopy and islet transplantation and diabetes models.

Recent research projects include:

  • Modulation of T lymphocyte activation during Type 1 diabetes and islet transplant rejection
  • Examining the role of cell surface and intracellular molecules in pancreatic islet function and beta cell survival (Cx36, RCAN1, SK1)
  • Investigating the interplay between vascular and endocrine cell types during islet transplantation

In addition to her research role, Dr Jessup teaches Anatomy and Histology topics within the MD course and supervises PhD research students.

Dr Jessup acknowledges support from generous funding bodies including NHMRC, Diabetes Australia, Channel 7 Children's Research Foundation, FMC Foundation and Department of Further Education, Employment, Science and Technology.

Qualifications
BBiotech(Hons); PhD
Honours, awards and grants

NHMRC Project Grant "Desmoglein-2; a novel lifeline to treat diabetes" CID, 2016-2018

Highest Impact Paper of the Year, Centre for Neuroscience, 2013 (winner); 2017 (runner-up)

Diabetes Australia Research Grant "The role of the calcineurin regulator RCAN1 in pancreatic islet function" CIA, 2013

Channel 7 Children's Research Foundation Grant "The importance of cell-to-cell interactions in juvenile (Type I) diabetes" CIA, 2013

Vice Chancellor's Award for Early Career Researchers, 2012

SA Young Tall Poppy Science Award, 2011


Key responsibilities

I teach into the first two years of the MD Course (Knowledge of Health and Illness) at Flinders University, including Histology and Anatomy practicals.

Topic coordinator
MMED9150 Human Homeostasis (MD)
Topic lecturer
MMED3203 Knowledge of Health and Illness 2
MMED3932 Body Systems
MMED3941 Human Musculoskeletal Anatomy
MMED9150 Knowledge of Health and Illness 1
Supervisory interests
Beta cells
Cell signalling
Corneal transplantation
Diabetes
Endothelial function
Immune mechanisms
Immunology
Insulin secretion
Islet transplantation
Structure/function of vascular beds
Vascular
Higher degree by research supervision
Current
Associate supervisor: GUT, ENDOCRINE CELLS, SEROTONIN (1), ENDOTHELIAL CELLS, DENGUE VIRUS (1), DIABETES, ZINC TRANSPORTERS, PANCREATIC BETA CELLS (1)
Completion
Associate supervisor: Dendritic cells, transplantation rejection and pancreatic islets (Univ Adelaide) (1), Gene therapy, pancreatic islet transplantation and diabetes (Univ. Adelaide) (1)
Higher degree by research student achievements
Ms Darling Rojas

Thomas E. Starzl Postdoctoral Fellowship in Transplantation Biology - NOV 2011

Ms Amy Hughes

PhD Dean's Commendation - APR 2013

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