Claire's research examines intracellular communication within pancreatic islets. Her work is focussed on a new potential cure for Type 1 diabetes - pancreatic islet transplantation. Recent work from this group has demonstrated the potential of a cellular cotherapy (endothelial progenitor cells) in improving islet transplantation outcomes. The Islet Biology Lab uses cellular and molecular techniques, diabetes and transplantation models, and confocal microscopy to probe the intricate interactions between insulin-producing beta cells and other cell types within the pancreatic islet.
NHMRC Project "Desmoglein-2; a novel lifeline to treat diabetes" CID, 2016-2018
Highest Impact Paper of the Year, Centre for Neuroscience, 2013
Vice Chancellor's Award for Early Career Researchers, 2012
SA Young Tall Poppy Science Award, 2011
My primary research interests focus on the vasculature of the pancreatic islet, and the relevance of cell signalling to diabetes. The dense network of capillaries is crucial for the sensitive detection of blood glucose and release of insulin. Many islets die when they are disconnected from their blood supply for transplantation purposes - limiting the success of islet transplantation. In collaboration with Dr Claudine Bonder in the Centre for Cancer Biology we are investigating the use of endothelial progenitor cells to swiftly reconnect the blood supply to transplanted islets and improve their function and survival. Visit my lab page for more!
As an Adjunct Senior Lecturer with the University of Adelaide, I work collaboratively with the Islet Transplantation and Dendritic Cell Biology Laboratory run by Prof Toby Coates.
Thomas E. Starzl Postdoctoral Fellowship in Transplantation Biology - NOV 2011
PhD Dean's Commendation - APR 2013
Find our latest lab publication here
Congrats Shane Grey and team on a fantastic new funding announcement
Congratulations to our collaborator and friend Claudine Bonder!
Making medical history in Adelaide
My lab is part of the Flinders Centre for Neuroscience
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