Associate Professor Michael Michael

Academic Status & Web Supervisor

College of Medicine and Public Health

place Flinders Medical Centre (4L:100)
GPO Box 2100, Adelaide 5001, South Australia

Michael Michael is the Cancer Research Program Lead in the Flinders Health and Medical Research Institute. He is also a Hospital Medical Scientist who leads the Gene Expression Laboratory at Flinders Centre for Innovation in Cancer. After helping to establish one of Australia’s first biotechnology companies, Michael moved to Flinders, in 1998, in the pursuit of biomarkers for colorectal cancer. He pioneered global profiling of microRNAs to identify associations with disease, particularly solid tumours. His interests have broadened to investigate the involvement of epigenetics and non-coding RNAs in various aspects of human development, metabolism and disease. However, the focus of his lab is still to deliver diagnostic tests that will inform clinical decision-making and to identify drug targets for novel therapeutics. Michael contributes to community and regulatory bodies, including the Gene Technology Technical Advisory Committee of the Office of the Gene Technology Regulator.


B.Sc (Hons) 1985 The University of Melbourne

Ph.D. (Genetics) 1998 The University of Melbourne

Honours, awards and grants

1989   Australian Postgraduate Research Award (Industry)

2013   Finalist, Unsung Hero of South Australian Science Awards

2014   High Commendation, Unsung Hero of South Australian Science Awards

Key responsibilities

2011 Gene Technology Technical Advisory Committee (Statutory), OGTR, Dept. Health, Australian Government

2012 Head, Gene Expression Laboratory, Dept. Gastroenterology and Hepatology, Flinders Medical Centre, Flinders Centre for Innovation in Cancer

2012 Co-director, Flinders Genomics Facility

2013 Director, Cell Screen SA: High Throughput Screening Facility - Drug Discovery and Functional Genomics

2017 Chair, Flinders Foundation Research Committee

2019 Flinders Foundation Board of Directors

2020 Lead - Cancer Research Program: Flinders Health and Medical Research Institute

2020 Board of South Australian Genomics Centre

Supervisory interests
Epigenetics and dietary regulation of gene expression
Exosome-mediated intercellular signalling
Gastrointestinal cancers, altered gene expression
MicroRNA-regulated gene expression
Higher degree by research supervision
Principal supervisor: Cancer cell metabolism (1), Cancer epigenetics (1)
Associate supervisor: Coronary bypass, kidney health, microRNAs, hypoxia (1), Radiation research, cell biology (1), Mesothelioma, gene expression (1), Vascular biology, gene expression (1), Plant epigenetics (1), Oncology, microRNA, therapeutic response (1), Breast cancer, genetics, driver mutations (1)
Principal supervisor: Colorectal cancer, microRNAs, diet, epigenetics (1)
Associate supervisor: Upper GI cancers, microRNAs, biomarkers (1), Radiation research, DNA methylation, genomic stability (1), Retinopathy, gene expression, microRNAs, hyperoxia (1), Prostate cancer, transcriptional regulation, androgen response (1), Epigenetics, Gene expression, Leukemia (1), microRNA biosynthesis, hypoxia, cancer cell biology (1)
Higher degree by research student achievements
Ayla Orang

3 Minute Thesis competition; winner Flinders University - SEP 2017

Saira Ali

3 Minute Thesis competition; runner-up & People's choice award Flinders University - AUG 2018

Ayla Orang

ASBMB Student Poster Prize; ComBio2018 - SEP 2018