Professor Michael Sorich

Professor in Pharmacology Clinical Pharmacology

College of Medicine and Public Health

place Flinders Medical Centre (5D:317)
GPO Box 2100, Adelaide 5001, South Australia

I am a clinical epidemiologist, biostatistician, and pharmacist with a primary research interest in the use of biological, chemical, and clinical markers to guide decisions regarding the most appropriate use of medicines (precision medicine). My current research primarily focuses on evaluation and evidence development with respect to precision medicine approaches informing the use of cancer medicines. This includes analysis of pooled clinical trial data, and evaluation of patient data from routine clinical care. Additionally, I research novel biomarkers of drug exposure to better inform drug dosing.

Qualifications
  • PhD
  • Graduate Diploma in Medical Statistics
  • Bachelor of Pharmacy Honours (1A)
  • Bachelor of Pharmacy
Honours, awards and grants

Selected Awards

  • 2008: South Australian Tall Poppy Award, Australian Institute of Policy and Science
  • 2006: Denis Wade Johnson & Johnson New Investigator Award, Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists
  • 2004: CJ Martin Postdoctoral Fellowship, National Health and Medical Research Council of Australia
  • 2003: New Investigator Award, Australasian Pharmaceutical Science Association

Selected Research Grants

  • ADMExosomes: A new paradigm for tracking variability in drug exposure. CIs: Rowland A, Sorich MJ, Makenzie P. NHMRC Project grant (2019-2021, ID 1128332)

    Sorich MJ. From Big Data to Precision Medicine: Integrated analysis of clinical trial and electronic health record data in lung cancer. Cancer Council SA, Beat Cancer Project Grant (2019, ID 1159924).

  • Improving the evaluation of new cancer therapies to expedite patient access. CIs: Karnon J, Sorich MJ, Ward R, Latimer N, Coory M. Project grant. NHMRC Project Grant (2017-2019, Grant ID 1128332)

  • Dynamic Prediction of Immune Checkpoint Inhibitor Response and Toxicity. CIs Sorich MJ, Gurney H, Kichenadasse G, McKinnon RA, Wiese MD, Rowland A. Cancer Council SA, Beat Cancer Project Grant (2017, GrantID 1127220)
  • Optimisation of the safety and efficacy of protein kinase inhibitors using endogenous and dietary biomarkers. CIs: Sorich MJ, Rowland A, Wiese M, Miners J, Gurney H. NHMRC Project grant. (2016-2018)
  • Personalised medicine markers of anti-EGFR antibody therapy in metastatic colorectal cancer: accelerating clinical translation with collaborative meta-analyses based on individual-participant data. Karapetis, C, Sorich MJ, McKinnon RA, Buyse M. Project grant. NHMRC (2015-2018)
  • Flinders Centre for Gastrointestinal Cancer Prevention. CIs: Watson D, Karapetis C, Young G, Wilson C, Fraser R, Reed R, Sorich M, Ratcliffe J, Woodman R, McKinnon R. Beat Cancer Hospital Research Package. (2014-2018).
Key responsibilities
  • Chair, Special Interest Group on Translational Research & Precision Medicine, International Pharmaceutical Federation (FIP)

  • Member, Board of Pharmaceutical Sciences, International Pharmaceutical Federation (FIP)
  • Member, International Scientific Programming Committee (ISPC) for the 7th Pharmaceutical Sciences World Congress (PSWC), Montreal (Canada) 2020
  • Member, Editorial Board of Translational Lung Cancer Research
  • Member, Editorial Board of Therapeutic Advances in Drug Safety
  • Member, Editorial Board of Translational Cancer Research
  • Member, Editorial Board of Clinical Pharmacology & Translational Medicine
  • Member, Executive Committee, Flinders Centre for Innovation in Cancer
  • Topic Coordinator, Principles of Pharmacology and Therapeutics (MMED9110), Flinders University
  • Topic Coordinator, Pharmacology for Advanced Professional Practice (MMED9111), Flinders University
  • Member, Master of Nursing (Nurse Practitioner) Course Advisory Committee, Flinders University
Research expertise
Clinical sciences
Pharmacology and pharmaceutical sciences
Statistics
Research interests
  • Precision/personalised medicine
  • Prediction modelling of outcomes of cancer medicines in advanced cancer
  • Novel methods for precision dosing of medicines
  • Evidence-based medicine, clinical epidemiology, decision analysis, pharmacoeconomics and meta-analysis
Topic coordinator
MMED9110 Principles of Pharmacology and Therapeutics
MMED9111 Pharmacology for Advanced Professional Practice
Topic lecturer
MMED3934 Principles of pharmacology and toxicology
PARA3006 Applied Pharmacology
MMED9110 Principles of Pharmacology and Therapeutics
MMED9111 Pharmacology for Advanced Professional Practice
NUTD3102 Nutrients Role & Function
MMED8203 Knowledge of Health and Illness 2
MMED8103 Knowledge of Health and Illness 1A
Supervisory interests
Clinical epidemiology
Clinical pharmacology
Clinician’s decision making
Evidence based medicine
Meta-analysis
Personalised medicine
Pharmacogenetics
Higher degree by research supervision
Current
Principal supervisor: Biomarkers of drug metabolism (1)
Associate supervisor: Drug exposure response relationships (1), Biomarkers of drug metabolism (1)
Publications
Expert for media contact
Precision medicine
Predication modelling in cancer
Available for contact via
Or contact the media team
+61 8 82012092
0427 398 713
Interests
  • Precision medicine
  • Predication modelling in cancer

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