Academic Status
College of Medicine and Public Health
A/Prof Apaja is the Head of the Organelle Proteostasis Diseases Laboratory.
I have endeavoured my research career to decipher how cells cope and reprogramme Protein Homeostasis (Proteostasis) Stress in human diseases, and specifically how post-translational signalling adapts cellular quality control surveillance and disposal systems to changing conditions.
We are focusing on identifying key proteostasis networks, post-translational modifications and targeted compounds to modulate transport, folding, recognition and disposal of membrane organelle/protein targets in brain diseases and cancers.
My laboratory combines screenings, omics and protein networks with biochemical and cell biological approaches in disease models.
Group Leader, Supervision, Leadership, Teaching, Management, Reviewer
-Proteostasis Networks
-Protein Quality Control
-Brain Diseases