Dr Shiwani Sharma has been pursuing ophthalmic research in the School of Medicine for more than seventeen years. She has undertaken many research projects including on corneal dystrophies, cataract, glaucoma, and published research findings in leading international scientific journals including Nature Genetics, Journal of Cell Science, American Journal of Human Genetics and Human Molecular Genetics. She has been an invited speaker at meetings of national and international scientific societies including the International Society for Eye Research, Asia and Oceania Society for Photobiology, and Australian Society of Biochemists and Molecular Biologists.
Dr Shiwani Sharma's research in Ophthalmology focuses on deciphering the molecular and cellular processes underlying eye diseases, with the objective of developing diagnostic, preventative and/or treatment strategies. She is particularly interested in genetically predisposed eye diseases such as cataract, glaucoma and corneal dystrophies with both early and late onset forms. Her research has defined the molecular mechanism of inherited congenital cataract in affected families. In NH&MRC funded research she is investigating the interaction of environmental and genetic factors and its contribution to aging related cataract, the leading cause of blindness worldwide. She is also investigating the mechanisms underlying genetic susceptibility factors in glaucoma, the major cause of irreversible blindness worldwide. In addition, she is investigating the pathophysiology of Fuchs' corneal endothelial dystrophy, one of the major indications for corneal grafting in developed countries, and keratoconus. She employes molecular and cellular biology techniques, and uses pathological specimens and cell-based and animal models for her research. She guides a team of research students and staff pursuing this research.
Vice-Chancellor’s Prize for Doctoral Thesis Excellence - APR 2016
NH&MRC Project grants Assessor
NH&MRC Program grants Assessor
Fight for Sight, UK, grant Assessor
ORIA project grants Assessor
Peer Reviewer for multiple scientific journals
Educator at the Eye Bank of South Australia Annual Training Day
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