The primary goal for the Australia-China Centre for Personal Health Technologies is to develop a consumer device capable of measuring a wide range of biomarkers from bodily fluids (e.g. sweat, saliva, blood or urine) which can be incorporated into a smartphone platform and link to e-health services for further analysis by medical professionals.
These results will provide real time health insights to assist in managing illnesses and improve the overall health of Australians. Personal health technology allows for personalised treatment to be provided based on information acquired on an individual’s specific condition.
The partnership, led by Flinders University and Nankai University, and involves a number of other cross-disciplinary partners to create these state-of-the-art personal medical devices.
This project received funding from the Australian Government as part of the Australia-China Science and Research Fund program and the Ministry of Science & Technology of the People’s Republic of China.
Research projects fall under the three research themes of the centre:
Our researchers are working with Aggregation Induced Emission Luminogens (AIEgens) to detect biological molecules. These are a novel type of advanced material that can provide superior sensitivity to other biomarker detection methods in either saliva, urine, sweat, blood or mucus.
The Centre is working with existing AIEgens as well as developing new AIEgens that meet a consumer healthcare need and have a commercial market.
The device will use a mobile phone in conjunction with a detection device (like a small box) to illuminate the test samples, indicating the presence of a specific disease or condition. It may also be used to monitor biomarker levels in people with long term conditions to indicate disease progression or even medication adherence.
Our researchers are working on a number of projects to ensure test results are communicated to the personal device, displayed in a way that people understand them and inform healthcare providers so that they can decide on appropriate follow up steps.
Projects include work on: user interface; data acquisition; management system and data analysis.
Professor Karen Reynolds
Director Australia-China Centre for Personal Health Technologies
Associate Professor Youhong Tang
Project Manager, Flinders University
Professor Richard Reed
Dr Bicheng Yao
La Trobe University
Dr Yuning Hong
La Trobe University
PhD Student, Flinders University
Dr Damian Tohl
Dr Meseret Teferra
Professor Dan Ding
Project Manager, Nankai University
Professor Anjun Qin
South China University of Technology
Professor Yinlong Wang
Shandong Academy of Sciences
Dr Ni Xi
Shenzhen AIEgen Biotech
Adam Di Fiore
Detection of biomarkers in body fluids using bioprobes based on aggregation-induced emission fluorogens, Xinyi Zhang, Bicheng Yao, Qi Hu, Yuning Hong , Angus Wallace, Karen Reynolds, Carolyn Ramsey, Anthony Maeder, Richard Reed and Youhong Tang.
Intramolecular motion-associated biomaterials for image-guided cancer surgery, Chao Chen, Youhong Tang, Dan Ding.
A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment, Tze Cin Owyong, Pramod Subedi, Jieru Deng, Dr. Elizabeth Hinde, Dr. Jason J. Paxman, Prof. Jonathan M. White,, Prof. Weisan Chen, Prof. Begoña Heras, Dr. Wallace W. H. Wong, Dr. Yuning Hong
A hyper-branched polymer tunes the size and enhances the fluorescent properties of aggregation-induced emission nanoparticles† Javad Tavakoli Nikita Joseph, Colin L. Raston and Youhong Tang
Synthetic fluorescent probes to apprehend calcium signalling in lipid droplet accumulation in microalgae—an updated review, Ahm Mohsinul Reza, Javad Tavakoli, Yabin Zhou, Jianguang Qin & Youhong Tang
Tuning aggregation-induced emission nanoparticle properties under thin film formation, Javad Tavakoli, Scott Pye, A. H. M. Mosinul Reza, Ni Xie d, Jian Qin, Colin L. Raston, Ben Zhong Tang and Youhong Tang.
Aggregation-Induced Emission Photosensitizers: From Molecular Design to Photodynamic Therapy, Jun Dai, Xia Wu, Siyang Ding, Xiaoding Lou, Fan Xia, Shixuan Wang and Yuning Hong.
Barbituric Acid Based Fluorogens: Synthesis, Aggregation-Induced Emission, and Protein Fibril Detection Siyang Ding, Bicheng Yao,Louis Schobben and Yuning Hong.
Diaminomaleonitrile-functionalised Schiff bases: synthesis, solvatochromism, and lysosome-specific imaging, Ding, S., Yao, B., Chen, M. Z., Liu, C., Owyong, T. C., Johnston, A., Hong, Y.
Fast surface immobilization of native proteins through catalyst-free amino-yne click bioconjugation, Yiru Zhang, Jianlei Shen, Rong Hu, Xiujuan Shi, Xianglong Hu, Benzhao He, Anjun Qin and Ben Zhong Tang
An AIE-Active Conjugated Polymer with High ROS-Generation Ability and Biocompatibility for Efficient Photodynamic Therapy of Bacterial Infections, Taotao Zhou, Rong Hu, Lirong Wang, Yanping Qiu, Guiquan Zhang, Qiyun Deng, Haiyan Zhang, Pingan Yin, Bo Situ, Chunlie Zhan, Anjun Qin, and Ben Zhong Tang.
Detection of kidney disease biomarkers based on fluorescence technology, Bicheng Yao, Marie-Claire Giela and Yuning Hong
Detection of Urinary Albumin Using a “Turn‐on” Fluorescent Probe with Aggregation‐Induced Emission Characteristics, Qi Hu, Dr. Bicheng Yao, Tze Cin Owyong, Sharon Prashanth, Changyu Wang, Xinyi Zhang, Dr. Wallace, W. H. Wong, Prof. Dr. Youhong Tang , Dr. Yuning Hong.
Optical-Based Biosensors and Their Portable Healthcare Devices for Detecting and Monitoring Biomarkers in Body Fluids, Pham, Anh T.T., Angus Wallace, Xinyi Zhang, Damian Tohl, Hao Fu, Clarence Chuah, Karen J. Reynolds, Carolyn Ramsey, and Youhong Tang
In Situ Monitored Vortex Fluidic-Mediated Protein Refolding/Unfolding Using an Aggregation-Induced Emission Bioprobe, Hu, Qi, Haozhen Hu, Xinyi Zhang, Kyle Fan, Yuning Hong, Colin L. Raston, and Youhong Tang
You consent to the use of our cookies if you proceed.