Mariann says, “Once you have been exposed to brain cancer, one becomes very determined to find a way to stop this insidious cancer, which due to its nature and location, leaves so little for the person afflicted to look forward to.”
By November 2019 ABC SA had raised an initial $2,400 donation that enabled the start of the researchers’ investigation into the ability of drug-like compounds to inhibit the growth of Glioblastoma multiforme (GBM), a common and aggressive type of brain tumour.
Current treatment includes brain surgery, radiotherapy and chemotherapies, all of which carry serious side effects that lower a patient's quality of life – and despite treatment, most patients die within two years of diagnosis.
“The initial donation from ABC SA allowed me to generate some very exciting results,” says Dr Manucat-Tan. “The preliminary study suggested that drugs targeting a particular protein found in brain fluid can be used to influence the growth of brain cancer cells.”
Now with the second donation of $5,600 from ABC SA, Dr Manucat-Tan is now looking to expand her research using brain organoids – a life-like model to study the human disease.
ABC SA is proud that its total donation of $8,000 will help to advance our understanding of adult brain cancer therapies.
“By supporting researchers at Flinders University, we believe our donation will inspire them to bring their absolute best skills and intellect to the cause,” says Mariann. “Noralyn is fresh, keen and inspired by possibility, and we know that the University is similarly keen for this work to be successful.”
Adult Brain Cancer Support Association dedicates its donation in memory of its members who have died from brain cancer.